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Recent advances in diffusion models have shown remarkable potential for antibody design, yet existing approaches apply uniform generation strategies that cannot adapt to each antigen's unique requirements. Inspired by B cell affinity…

Machine Learning · Computer Science 2025-08-19 Hanqi Feng , Peng Qiu , Mengchun Zhang , Yiran Tao , You Fan , Jingtao Xu , Barnabas Poczos

We learn about the world from a diverse range of sensory information. Automated systems lack this ability as investigation has centred on processing information presented in a single form. Adapting architectures to learn from multiple…

Machine Learning · Computer Science 2020-10-27 Jason Armitage , Shramana Thakur , Rishi Tripathi , Jens Lehmann , Maria Maleshkova

Operational maturity of biological control systems have fuelled the inspiration for a large number of mathematical and logical models for control, automation and optimisation. The human brain represents the most sophisticated control…

Neural and Evolutionary Computing · Computer Science 2017-09-13 Shubham Dokania , Ayush Chopra , Feroz Ahmad , Anil Singh Parihar

Large Language Models (LLMs) possess substantial reasoning capabilities and are increasingly applied to optimization tasks, particularly in synergy with evolutionary computation. However, while recent surveys have explored specific aspects…

Neural and Evolutionary Computing · Computer Science 2026-01-08 Yisong Zhang , Ran Cheng , Guoxing Yi , Kay Chen Tan

Designing high-performance optical lenses entails exploring a high-dimensional, tightly constrained space of surface curvatures, glass choices, element thicknesses, and spacings. In practice, standard optimizers (e.g., gradient-based local…

Neural and Evolutionary Computing · Computer Science 2026-01-30 Kirill Antonov , Teus Tukker , Tiago Botari , Thomas H. W. Bäck , Anna V. Kononova , Niki van Stein

In this work, a new multiobjective optimization algorithm called multiobjective learner performance-based behavior algorithm is proposed. The proposed algorithm is based on the process of transferring students from high school to college.…

Neural and Evolutionary Computing · Computer Science 2022-01-31 Chnoor M. Rahman , Tarik A. Rashid , Aram Mahmood Ahmed , Seyedali Mirjalili

We present a generalized theoretical framework for olfactory representation and plasticity, using the theory of smooth manifolds and sheaves to depict categorical odor learning via distributed neural computation. Beginning with the space of…

Neurons and Cognition · Quantitative Biology 2023-10-13 Jack A. Cook , Thomas A. Cleland

This paper investigates distributed zeroth-order feedback optimization in multi-agent systems with coupled constraints, where each agent operates its local action vector and observes only zeroth-order information to minimize a global cost…

Optimization and Control · Mathematics 2024-10-17 Yingpeng Duan , Yujie Tang

The exploration-exploitation trade-off is central to sequential decision-making and black-box optimization, yet how Large Language Models (LLMs) reason about and manage this trade-off remains poorly understood. Unlike Bayesian Optimization,…

Machine Learning · Computer Science 2026-04-01 Andrea Carbonati , Mohammadsina Almasi , Hadis Anahideh

In the primary visual cortex of primates and carnivores, functional architecture can be characterized by maps of various stimulus features such as orientation preference (OP), ocular dominance (OD), and spatial frequency. It is a…

Neurons and Cognition · Quantitative Biology 2015-05-27 Lars Reichl , Dominik Heide , Siegrid Löwel , Justin C. Crowley , Matthias Kaschube , Fred Wolf

In this paper, we propose a novel concept for engineered molecular communication (MC) systems inspired by animal olfaction. We focus on a multi-user scenario where transmitters employ unique mixtures of different types of signaling…

Information Theory · Computer Science 2022-04-19 Vahid Jamali , Helene M. Loos , Andrea Buettner , Robert Schober , H. Vincent Poor

Multi-agent systems are increasingly widespread in a range of application domains, with optimization and learning underpinning many of the tasks that arise in this context. Different approaches have been proposed to enable the cooperative…

Optimization and Control · Mathematics 2025-09-04 Nicola Bastianello , Luca Schenato , Ruggero Carli

We develop a novel multi-objective reinforcement learning (MORL) framework to jointly optimize wireless network selection and autonomous driving policies in a multi-band vehicular network operating on conventional sub-6GHz spectrum and…

Machine Learning · Computer Science 2025-06-17 Zijiang Yan , Hina Tabassum

Molecular optimization is a crucial yet complex and time-intensive process that often acts as a bottleneck for drug development. Traditional methods rely heavily on trial and error, making multi-objective optimization both time-consuming…

Biomolecules · Quantitative Biology 2025-03-06 Jiajun Yu , Yizhen Zheng , Huan Yee Koh , Shirui Pan , Tianyue Wang , Haishuai Wang

Fabricating neural models for a wide range of mobile devices demands for a specific design of networks due to highly constrained resources. Both evolution algorithms (EA) and reinforced learning methods (RL) have been dedicated to solve…

Neural and Evolutionary Computing · Computer Science 2019-01-17 Xiangxiang Chu , Bo Zhang , Ruijun Xu , Hailong Ma

The majority of multi-agent system (MAS) implementations aim to optimise agents' policies with respect to a single objective, despite the fact that many real-world problem domains are inherently multi-objective in nature. Multi-objective…

Multiagent Systems · Computer Science 2020-11-17 Roxana Rădulescu , Patrick Mannion , Diederik M. Roijers , Ann Nowé

Most of the real-world problems are multimodal in nature that consists of multiple optimum values. Multimodal optimization is defined as the process of finding multiple global and local optima (as opposed to a single solution) of a…

Neural and Evolutionary Computing · Computer Science 2022-08-24 Shatendra Singh , Aruna Tiwari

Multi-label classification consists in classifying an instance into two or more classes simultaneously. It is a very challenging task present in many real-world applications, such as classification of biology, image, video, audio, and text.…

Machine Learning · Computer Science 2020-04-03 Thiago Zafalon Miranda , Diorge Brognara Sardinha , Márcio Porto Basgalupp , Yaochu Jin , Ricardo Cerri

Optimal Learning Machines (OLM) are systems that extract maximally informative representation of the environment they are in contact with, or of the data they are presented. It has recently been suggested that these systems are…

Data Analysis, Statistics and Probability · Physics 2020-01-29 Matteo Marsili

Recordings from neurons in the insects' olfactory primary processing center, the antennal lobe (AL), reveal that the AL is able to process the input from chemical receptors into distinct neural activity patterns, called olfactory neural…

Neurons and Cognition · Quantitative Biology 2014-08-27 Eli Shlizerman , Jeffrey A. Riffell , J. Nathan Kutz
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