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Cells modify their volume in response to changes in osmotic pressure but it is usually assumed that other active shape variations do not involve significant volume fluctuations. Here we report experiments demonstrating that water transport…

Bacteria commonly inhabit porous environments such as host tissues, soil, and marine sediments, where complex geometries constrain and redirect their motion. Although bacterial motility has been studied in porous media, the roles of cell…

Soft Condensed Matter · Physics 2025-12-22 David Gao , Zeyuan Wang , Mihika Jain , Arnold J. T. M. Mathijssen , Ran Tao

Eukaryotic cells are large enough to detect signals and then orient to them by differentiating the signal strength across the length and breadth of the cell. Amoebae, fibroblasts, neutrophils and growth cones all behave in this way. Little…

Cell Behavior · Quantitative Biology 2008-05-19 Liang Li , Simon F. Norrelykke , Edward C. Cox

Biological tissues have been observed to display emergent fluid-like properties, owing to physical interactions between cells. However, it remains unclear in general how these fluid-like properties affect tissue structure and function.…

Soft Condensed Matter · Physics 2026-02-24 Giulia L. Celora , Benjamin J. Walker , Mohit P. Dalwadi , Philip Pearce

Anomalous transport processes in which the variance of the distance travelled does not necessarily increase linearly with time are modelled using the formalism of continuous time random walks. We compute particle propagators which have the…

Astrophysics · Physics 2011-05-23 B. R. Ragot , J. G. Kirk

Biological membranes are host to proteins and molecules which may form domain-like structures resulting in spatially-varying material properties. Vesicles with such heterogeneous membranes can exhibit intricate shapes at equilibrium and…

Soft Condensed Matter · Physics 2023-06-22 Prerna Gera , David Salac , Saverio E. Spagnolie

Water flow in plant tissues takes place in two different physical domains separated by semipermeable membranes: cell insides and cell walls. The assembly of all cell insides and cell walls are termed symplast and apoplast, respectively.…

Analysis of PDEs · Mathematics 2013-05-28 Andrés Chavarría-Krauser , Mariya Ptashnyk

Viscous streaming is an efficient mechanism to exploit inertia at the microscale for flow control. While streaming from rigid features has been thoroughly investigated, when body compliance is involved, as in biological settings, little is…

Fluid Dynamics · Physics 2022-02-22 Yashraj Bhosale , Tejaswin Parthasarathy , Mattia Gazzola

In Nature, liquids often circulate in channels textured with leaflets, cilia or porous walls that deform with the flow. These soft structures are optimized to passively control flows and inspire the design of novel microfluidic and soft…

Soft Condensed Matter · Physics 2020-08-19 Martin Brandenbourger , Adrien Dangremont , Rudolf Sprik , Corentin Coulais

With exquisite precision and reproducibility, cells orchestrate the cooperative action of thousands of nanometer-sized molecular motors to carry out mechanical tasks at much larger length scales, such as cell motility, division and…

Soft Condensed Matter · Physics 2013-01-08 Tim Sanchez , Daniel T. N. Chen , Stephen J. DeCamp , Michael Heymann , Zvonimir Dogic

We investigate the dynamics of a colony of crawling, proliferating cells with a minimal, mechanical cell model. The cells consist of two disks, modelling the cell body and a pseudopod, connected by a finite extensible spring. The cells…

Cell Behavior · Quantitative Biology 2019-04-11 Simon K. Schnyder , John J. Molina , Ryoichi Yamamoto

Many natural and industrial processes rely on constrained transport, such as proteins moving through cells, particles confined in nanocomposite materials or gels, individuals in highly dense collec- tives and vehicular traffic conditions.…

The fast blood stream of animals is associated with large shear stresses. Consequently, blood cells have evolved a special morphology and a specific internal architecture allowing them to maintain their integrity over several weeks. For…

Subcellular Processes · Quantitative Biology 2022-10-12 Serge Dmitrieff , Adolfo Alsina , Aastha Mathur , François Nédélec

The prevalence of multicellular organisms is due in part to their ability to form complex structures. How cells pack in these structures is a fundamental biophysical issue, underlying their functional properties. However, much remains…

The movement of ionic solutions is an essential part of biology and technology. Fluidics, from nano- to micro- to microfluidics, is a burgeoning area of technology which is all about the movement of ionic solutions, on various scales. Many…

Quantitative Methods · Quantitative Biology 2018-06-08 Shixin Xu , Bob Eisenberg , Zilong Song , Huaxiong Huang

Many motile biological cells navigate along concentration gradients of signaling molecules: This chemotaxis guides for instance sperm cells from marine invertebrates, which have to find egg cells in the ocean. While chemotaxis has been…

Biological Physics · Physics 2022-09-21 Steffen Lange , Benjamin M. Friedrich

Contact inhibition plays a crucial role in the motility of cells, the process of wound healing, and the formation of tumors. By mimicking the mechanical motion of calls crawling on a substrate using a pseudopod, we constructed a minimal…

Soft Condensed Matter · Physics 2016-11-28 Simon Kaspar Schnyder , Yuki Tanaka , John Jairo Molina , Ryoichi Yamamoto

How finite-sized material lines stretch in chaotic (mono-scale) and turbulent (multi-scale) flows remains a central but unresolved problem that governs mixing, transport and reaction. We show elongation is controlled by a finite-sampling…

Fluid Dynamics · Physics 2026-04-21 Daniel Lester , Marco Dentz

Active cellular transport is a fundamental mechanism for protein and vesicle delivery, cell cycle and molecular degradation. Viruses can hijack the transport system and use it to reach the nucleus. Most transport processes consist of…

Quantitative Methods · Quantitative Biology 2009-11-13 T. Lagache , D. Holcman

We investigate the transport dynamics of elongated particles in cellular vortical flows that undergo spatial oscillations over time. Experimental flow visualizations reveal mixed flow fields with chaotic and elliptic regions coexisting.…

Fluid Dynamics · Physics 2025-08-14 Shiyuan Hu , Xiuyuan Yang , Nan Luo , Jun Zhang , Xingkun Man