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Long DNA molecules can be mapped by cutting them with restriction enzymes inside a narrow channel. Once cut, the individual fragments thus produced move away from each other due to diffusion and entropic effects. We investigate how long it…

Soft Condensed Matter · Physics 2025-06-11 Hanyang. Wang , Gary W Slater

The single-file problem of N particles in one spatial dimension is analyzed, when each particle has a randomly distributed diffusion constant D sampled in a density $\rho(D)$. The averaged one-particle distributions of the edge particles…

Statistical Mechanics · Physics 2009-10-31 Claude Aslangul

Diffusion behavior of Brownian particles in confined spaces was studied for the displacements notably shorter than the confinement size. The confinements, resembling structure of porous solids, were modeled using a spatially-varying…

Disordered Systems and Neural Networks · Physics 2016-11-24 Daniel Schneider , Rustem Valiullin , Nail Fatkullin

We derive and study a theoretical description for single file diffusion, i.e., diffusion in a one dimensional lattice of particles with hard core interaction. It is well known that for this system a tagged particle has anomalous diffusion…

Statistical Mechanics · Physics 2013-10-08 Gonzalo Suárez , Miguel Hoyuelos , Héctor O. Mártin

We study a minimal model of active transport in crowded single-file environments which generalises the emblematic model of single file diffusion to the case when the tracer particle (TP) performs either an autonomous directed motion or is…

Statistical Mechanics · Physics 2013-03-13 P. Illien , O. Bénichou , C. Mejía-Monasterio , G. Oshanin , R. Voituriez

We investigate the single-file dynamics of a tagged particle in a system consisting of N hardcore interacting particles (the particles cannot pass each other) which are diffusing in a one-dimensional system where the particles have…

Statistical Mechanics · Physics 2009-11-13 Tobias Ambjornsson , Ludvig Lizana , Michael A. Lomholt , Robert J. Silbey

Single-file diffusion is a paradigmatic model for the transport of Brownian colloidal particles in narrow one-dimensional channels, such as those found in certain porous media, where the particles cannot cross each other. We consider a…

Statistical Mechanics · Physics 2025-01-07 Benjamin Sorkin , David S. Dean

A rapidly increasing number of systems is identified in which the stochastic motion of tracer particles follows the Brownian law $\langle\mathbf{r}^2(t) \rangle\simeq Dt$ yet the distribution of particle displacements is strongly…

Statistical Mechanics · Physics 2019-01-30 V. Sposini , A. V. Chechkin , R. Metzler

The one-dimensional symmetric exclusion process, the simplest interacting particle process, is a lattice-gas made of particles that hop symmetrically on a discrete line respecting hard-core exclusion. The system is prepared on the infinite…

Statistical Mechanics · Physics 2017-04-26 T. Imamura , K. Mallick , T. Sasamoto

We study the position of a biased tracer particle (TP) in a bath of hardcore particles moving on a lattice of arbitrary dimension and in contact with a reservoir. Starting from the master equation satisfied by the joint probability of the…

Statistical Mechanics · Physics 2015-12-09 Pierre Illien , Olivier Bénichou , Gleb Oshanin , Raphaël Voituriez

We study the statistics of a tagged particle in single-file diffusion, a one-dimensional interacting infinite-particle system in which the order of particles never changes. We compute the two-time correlation function for the displacement…

Statistical Mechanics · Physics 2016-04-18 P. L. Krapivsky , Kirone Mallick , Tridib Sadhu

The dynamics of hard-core interacting Brownian particles in an external potential field is studied in one dimension. Using the Jepsen line we find a very general and simple formula relating the motion of the tagged center particle, with the…

Statistical Mechanics · Physics 2010-04-22 E. Barkai , R. Silbey

Active particles may happen to be confined in channels so narrow that they cannot overtake each other (Single File conditions). This interesting situation reveals nontrivial physical features as a consequence of the strong inter-particle…

Statistical Mechanics · Physics 2015-06-19 Emanuele Locatelli , Fulvio Baldovin , Enzo Orlandini , Matteo Pierno

We study the Single File Diffusion (SFD) of a cyclic chain of particles that cannot cross each other, in a thermal bath, with long ranged interactions, and arbitrary damping. We present simulations that exhibit new behaviors specifically…

Statistical Mechanics · Physics 2015-05-27 Jean-Baptiste Delfau , Christophe Coste , Michel Saint-Jean

30% of the DNA in E. coli bacteria is covered by proteins. Such high degree of crowding affect the dynamics of generic biological processes (e.g. gene regulation, DNA repair, protein diffusion etc.) in ways that are not yet fully…

Statistical Mechanics · Physics 2015-06-23 Sebastian Ahlberg , Tobias Ambjörnsson , Ludvig Lizana

A topic of intense current investigation pursues the question how the highly crowded environment of biological cells affects the dynamic properties of passively diffusing particles. Motivated by recent experiments we report results of…

Statistical Mechanics · Physics 2016-09-28 Surya K. Ghosh , Andrey G. Cherstvy , Denis S. Grebenkov , Ralf Metzler

We summarise different results on the diffusion of a tracer particle in lattice gases of hard-core particles with stochastic dynamics, which are confined to narrow channels -- single-files, comb-like structures and quasi-one-dimensional…

Statistical Mechanics · Physics 2018-11-14 O. Benichou , P. Illien , G. Oshanin , A. Sarracino , R. Voituriez

The effective diffusivity of Brownian tracer particles confined in periodic micro-channels is smaller than the microscopic diffusivity due to entropic trapping. Here, we study diffusion in two-dimensional periodic channels whose…

Statistical Mechanics · Physics 2019-05-29 M. Mangeat , T. Guérin , D. S. Dean

Space dependent diffusion of micrometer sized particles has been directly observed using digital video microscopy. The particles were trapped between two nearly parallel walls making their confinement position dependent. Consequently, not…

Statistical Mechanics · Physics 2009-10-31 P. Lancon , G. Batrouni , L. Lobry , N. Ostrowsky

Density-dependent diffusion is a widespread phenomenon in nature. We have examined the density-dependent diffusion behavior of some biological processes such as tumor growth and invasion [23]. Here, we extend our previous work by developing…

Statistical Mechanics · Physics 2022-02-14 Ahmed M. Fouad , Marwa M. Fouad