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Probabilistic artificial neural networks offer intriguing prospects for enabling the uncertainty of artificial intelligence methods to be described explicitly in their function; however, the development of techniques that quantify…

Artificial Intelligence · Computer Science 2023-11-23 James B. Aimone , William Severa , J. Darby Smith

In neuroscience, synaptic plasticity refers to the set of mechanisms driving the dynamics of neuronal connections, called synapses and represented by a scalar value, the synaptic weight. A Spike-Timing Dependent Plasticity (STDP) rule is a…

Probability · Mathematics 2021-11-17 Philippe Robert , Gaetan Vignoud

The brain can learn to execute a wide variety of tasks quickly and efficiently. Nevertheless, most of the mechanisms that enable us to learn are unclear or incredibly complicated. Recently, considerable efforts have been made in…

Neural and Evolutionary Computing · Computer Science 2023-03-28 Mohammad Modiri

In timing-based neural codes, neurons have to emit action potentials at precise moments in time. We use a supervised learning paradigm to derive a synaptic update rule that optimizes via gradient ascent the likelihood of postsynaptic firing…

Neurons and Cognition · Quantitative Biology 2007-05-23 Jean-Pascal Pfister , Taro Toyoizumi , David Barber , Wulfram Gerstner

Using a realistic model of activity dependent dynamical synapses and a standard integrate and fire neuron model we study, both analytically and numerically, the conditions in which a postsynaptic neuron efficiently detects temporal…

Neurons and Cognition · Quantitative Biology 2007-05-23 Jorge F. Mejias , Joaquin J. Torres

Neural processes (NPs) constitute a family of variational approximate models for stochastic processes with promising properties in computational efficiency and uncertainty quantification. These processes use neural networks with latent…

Machine Learning · Computer Science 2020-11-03 Qi Wang , Herke van Hoof

Asynchrony, overlaps and delays in sensory-motor signals introduce ambiguity as to which stimuli, actions, and rewards are causally related. Only the repetition of reward episodes helps distinguish true cause-effect relationships from…

Neural and Evolutionary Computing · Computer Science 2014-09-10 Andrea Soltoggio

Uncertainty estimation for machine learning models is of high importance in many scenarios such as constructing the confidence intervals for model predictions and detection of out-of-distribution or adversarially generated points. In this…

Machine Learning · Computer Science 2022-05-06 Kirill Fedyanin , Evgenii Tsymbalov , Maxim Panov

In this work we study the detection of weak stimuli by spiking neurons in the presence of certain level of noisy background neural activity. Our study has focused in the realistic assumption that the synapses in the network present…

Neurons and Cognition · Quantitative Biology 2009-06-04 Jorge F. Mejias , Joaquin J. Torres

The plasticity of the conduction delay between neurons plays a fundamental role in learning. However, the exact underlying mechanisms in the brain for this modulation is still an open problem. Understanding the precise adjustment of…

Neural and Evolutionary Computing · Computer Science 2020-11-19 Alireza Nadafian , Mohammad Ganjtabesh

To date, it is still impossible to sample the entire mammalian brain with single-neuron precision. This forces one to either use spikes (focusing on few neurons) or to use coarse-sampled activity (averaging over many neurons, e.g. LFP).…

Neurons and Cognition · Quantitative Biology 2022-12-12 Joao Pinheiro Neto , Franz Paul Spitzner , Viola Priesemann

Spiking neural networks (SNNs) are recurrent models that can leverage sparsity in input time series to efficiently carry out tasks such as classification. Additional efficiency gains can be obtained if decisions are taken as early as…

Neural and Evolutionary Computing · Computer Science 2023-12-19 Jiechen Chen , Sangwoo Park , Osvaldo Simeone

We show that the local Spike Timing-Dependent Plasticity (STDP) rule has the effect of regulating the trans-synaptic weights of loops of any length within a simulated network of neurons. We show that depending on STDP's polarity, functional…

Neurons and Cognition · Quantitative Biology 2010-03-23 James R. Kozloski , Guillermo A. Cecchi

We investigate the efficient transmission and processing of weak, subthreshold signals in a realistic neural medium in the presence of different levels of the underlying noise. Assuming Hebbian weights for maximal synaptic conductances --…

Biological Physics · Physics 2015-08-19 Joaquin J. Torres , Irene Elices , J. Marro

We study the synchronization of two model neurons coupled through a synapse having an activity-dependent strength. Our synapse follows the rules of Spike-Timing Dependent Plasticity (STDP). We show that this plasticity of the coupling…

Biological Physics · Physics 2009-11-07 Valentin P. Zhigulin , Mikhail I. Rabinovich , Ramon Huerta , Henry D. I. Abarbanel

Photoplethysmography (PPG) signals encode information about relative changes in blood volume that can be used to assess various aspects of cardiac health non-invasively, e.g.\ to detect atrial fibrillation (AF) or predict blood pressure…

Machine Learning · Computer Science 2025-05-19 Ciaran Bench , Vivek Desai , Mohammad Moulaeifard , Nils Strodthoff , Philip Aston , Andrew Thompson

We use a biophysical model of a local neuronal circuit to study the implications of synaptic plasticity for the detection of weak sensory stimuli. Networks with fast plastic coupling show behavior consistent with stochastic resonance.…

Neurons and Cognition · Quantitative Biology 2009-11-13 Vladislav Volman , Herbert Levine

We study the characteristics of weak signal detection by a recurrent neuronal network with plastic synaptic coupling. It is shown that in the presence of an asynchronous component in synaptic transmission, the network acquires selectivity…

Neurons and Cognition · Quantitative Biology 2015-05-13 Vladislav Volman , Herbert Levine

A key question in neuroscience is at which level functional meaning emerges from biophysical phenomena. In most vertebrate systems, precise functions are assigned at the level of neural populations, while single-neurons are deemed…

Neurons and Cognition · Quantitative Biology 2017-03-17 Wieland Brendel , Ralph Bourdoukan , Pietro Vertechi , Christian K. Machens , Sophie Denéve

Most normative models in computational neuroscience describe the task of learning as the optimisation of a cost function with respect to a set of parameters. However, learning as optimisation fails to account for a time varying environment…

Neurons and Cognition · Quantitative Biology 2020-08-10 Jannes Jegminat , Jean-Pascal Pfister