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How can we build agents that keep learning from experience, quickly and efficiently, after their initial training? Here we take inspiration from the main mechanism of learning in biological brains: synaptic plasticity, carefully tuned by…

Neural and Evolutionary Computing · Computer Science 2018-08-01 Thomas Miconi , Jeff Clune , Kenneth O. Stanley

Understanding how biological neural networks are shaped via local plasticity mechanisms can lead to energy-efficient and self-adaptive information processing systems, which promises to mitigate some of the current roadblocks in edge…

Neural and Evolutionary Computing · Computer Science 2025-04-10 Willian Soares Girão , Nicoletta Risi , Elisabetta Chicca

How can neural networks learn to efficiently represent complex and high-dimensional inputs via local plasticity mechanisms? Classical models of representation learning assume that input weights are learned via pairwise Hebbian-like…

Neurons and Cognition · Quantitative Biology 2022-10-04 Fabian Alexander Mikulasch , Lucas Rudelt , Viola Priesemann

Brain plasticity refers to brain's ability to change neuronal connections, as a result of environmental stimuli, new experiences, or damage. In this work, we study the effects of the synaptic delay on both the coupling strengths and…

Neurons and Cognition · Quantitative Biology 2018-11-14 E. L. Lameu , E. E. N. Macau , F. S. Borges , K. C. Iarosz , I. L. Caldas , R. R. Borges , P. R. Protachevicz , R. L. Viana , A. M. Batista

A recent breakthrough in biologically-plausible normative frameworks for dimensionality reduction is based upon the similarity matching cost function and the low-rank matrix approximation problem. Despite clear biological interpretation,…

Neurons and Cognition · Quantitative Biology 2025-06-09 Veronica Centorrino , Francesco Bullo , Giovanni Russo

In this paper, we derive a new model of synaptic plasticity, based on recent algorithms for reinforcement learning (in which an agent attempts to learn appropriate actions to maximize its long-term average reward). We show that these direct…

Machine Learning · Computer Science 2019-11-19 Peter L. Bartlett , Jonathan Baxter

Recently, the use of bio-inspired learning techniques such as Hebbian learning and its closely-related Spike-Timing-Dependent Plasticity (STDP) variant have drawn significant attention for the design of compute-efficient AI systems that can…

Neural and Evolutionary Computing · Computer Science 2024-11-19 Ali Safa

Hebbian learning theory is rooted in Pavlov's Classical Conditioning. While mathematical models of the former have been proposed and studied in the past decades, especially in spin glass theory, only recently it has been numerically shown…

Disordered Systems and Neural Networks · Physics 2024-10-11 Daniele Lotito , Miriam Aquaro , Chiara Marullo

Hebbian learning is a key principle underlying learning in biological neural networks. We relate a Hebbian spike-timing-dependent plasticity rule to noisy gradient descent with respect to a non-convex loss function on the probability…

Machine Learning · Computer Science 2026-01-14 Niklas Dexheimer , Sascha Gaudlitz , Johannes Schmidt-Hieber

Brain plasticity, also known as neuroplasticity, is a fundamental mechanism of neuronal adaptation in response to changes in the environment or due to brain injury. In this review, we show our results about the effects of synaptic…

Biological neural networks self-organize according to local synaptic modifications to produce stable computations. How modifications at the synaptic level give rise to such computations at the network level remains an open question.…

Neurons and Cognition · Quantitative Biology 2026-01-21 David Lipshutz , Robert J. Lipshutz

Developmental approaches to neural architecture search grow functional networks from compact genomes through self-organisation, but the resulting networks operate with fixed post-growth weights. We characterise Hebbian and anti-Hebbian…

Robotics · Computer Science 2026-04-08 Sergii Medvid , Andrii Valenia , Mykola Glybovets

In recent years self organised critical neuronal models have provided insights regarding the origin of the experimentally observed avalanching behaviour of neuronal systems. It has been shown that dynamical synapses, as a form of short-term…

Adaptation and Self-Organizing Systems · Physics 2018-03-28 L. Michiels van Kessenich , M. Luković , L. de Arcangelis , H. J. Herrmann

We study the capacity of Hodgkin-Huxley neuron in a network to change temporarily or permanently their connections and behavior, the so called spike timing-dependent plasticity (STDP), as a function of their synchronous behavior. We…

Synaptic delays play a crucial role in biological neuronal networks, where their modulation has been observed in mammalian learning processes. In the realm of neuromorphic computing, although spiking neural networks (SNNs) aim to emulate…

Neural and Evolutionary Computing · Computer Science 2025-06-19 Marissa Dominijanni , Alexander Ororbia , Kenneth W. Regan

One of the most striking capabilities behind the learning mechanisms of the brain is the adaptation, through structural and functional plasticity, of its synapses. While synapses have the fundamental role of transmitting information across…

Neural and Evolutionary Computing · Computer Science 2024-06-10 Andrea Ferigo , Elia Cunegatti , Giovanni Iacca

Synaptic plasticity typically produces heavy-tailed distributions of synaptic strengths, consisting of a few strong connections among many weaker ones. Meanwhile, structural plasticity relies on distinct signaling cascades to reshape…

Neurons and Cognition · Quantitative Biology 2026-01-06 Jia Li , Cees van Leeuwen , Roman Bauer , Ilias Rentzeperis

Lateral inhibition models coupled with Hebbian plasticity have been shown to learn factorised causal representations of input stimuli, for instance, oriented edges are learned from natural images. Currently, these models require the…

Neurons and Cognition · Quantitative Biology 2025-01-07 Henrique Reis Aguiar , Matthias H. Hennig

A fundamental question in neuroscience is how structure and function of neural systems are related. We study this interplay by combining a familiar auto-associative neural network with an evolving mechanism for the birth and death of…

Adaptation and Self-Organizing Systems · Physics 2019-04-26 Ana P. Millán , J. J. Torres , S. Johnson , J. Marro

The plasticity property of biological neural networks allows them to perform learning and optimize their behavior by changing their configuration. Inspired by biology, plasticity can be modeled in artificial neural networks by using Hebbian…

Neural and Evolutionary Computing · Computer Science 2020-12-21 Anil Yaman , Giovanni Iacca , Decebal Constantin Mocanu , George Fletcher , Mykola Pechenizkiy