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In this manuscript, we automate the procedure of grading of diabetic retinopathy and macular edema from fundus images using an ensemble of convolutional neural networks. The availability of limited amount of labeled data to perform…

Computer Vision and Pattern Recognition · Computer Science 2018-09-13 Avinash Kori , Sai Saketh Chennamsetty , Mohammed Safwan K. P. , Varghese Alex

There is an increasing number of medical use-cases where classification algorithms based on deep neural networks reach performance levels that are competitive with human medical experts. To alleviate the challenges of small dataset sizes,…

Computer Vision and Pattern Recognition · Computer Science 2021-06-28 Vignesh Srinivasan , Nils Strodthoff , Jackie Ma , Alexander Binder , Klaus-Robert Müller , Wojciech Samek

In this report, we applied integrated gradients to explaining a neural network for diabetic retinopathy detection. The integrated gradient is an attribution method which measures the contributions of input to the quantity of interest. We…

Artificial Intelligence · Computer Science 2017-10-19 Linyi Li , Matt Fredrikson , Shayak Sen , Anupam Datta

The retina is an essential component of the visual system, and maintaining eyesight depends on the timely and accurate detection of disorders. The early-stage detection and severity classification of Diabetic Retinopathy (DR), a significant…

Retinopathy of Prematurity (ROP) is a fibrovascular proliferative disorder, which affects the developing peripheral retinal vasculature of premature infants. Early detection of ROP is possible in stage 1 and stage 2 characterized by…

Image and Video Processing · Electrical Eng. & Systems 2021-09-06 Supriti Mulay , Keerthi Ram , Mohanasankar Sivaprakasam , Anand Vinekar

Fundus photography is the primary method for retinal imaging and essential for diabetic retinopathy prevention. Automated segmentation of fundus photographs would improve the quality, capacity, and cost-effectiveness of eye care screening…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Jan Kukačka , Anja Zenz , Marcel Kollovieh , Dominik Jüstel , Vasilis Ntziachristos

Diabetic retinopathy (DR), a microvascular complication of diabetes and a leading cause of preventable blindness, is projected to affect more than 130 million individuals worldwide by 2030. Early identification is essential to reduce…

Quantitative Methods · Quantitative Biology 2025-11-12 Jophy Lin

Background and objective: Diabetes is a chronic pathology which is affecting more and more people over the years. It gives rise to a large number of deaths each year. Furthermore, many people living with the disease do not realize the…

Diabetic retinopathy (DR) screening is instrumental in preventing blindness, but faces a scaling challenge as the number of diabetic patients rises. Risk stratification for the development of DR may help optimize screening intervals to…

Segmentation plays a crucial role in diagnosis. Studying the retinal vasculatures from fundus images help identify early signs of many crucial illnesses such as diabetic retinopathy. Due to the varying shape, size, and patterns of retinal…

Image and Video Processing · Electrical Eng. & Systems 2021-09-07 Shreshth Saini , Geetika Agrawal

We propose a convolution neural network based algorithm for simultaneously diagnosing diabetic retinopathy and highlighting suspicious regions. Our contributions are two folds: 1) a network termed Zoom-in-Net which mimics the zoom-in…

Computer Vision and Pattern Recognition · Computer Science 2017-06-15 Zhe Wang , Yanxin Yin , Jianping Shi , Wei Fang , Hongsheng Li , Xiaogang Wang

In this paper, an ensemble-based method for the screening of diabetic retinopathy (DR) is proposed. This approach is based on features extracted from the output of several retinal image processing algorithms, such as image-level (quality…

Computer Vision and Pattern Recognition · Computer Science 2014-11-03 Balint Antal , Andras Hajdu

Stroke is globally a major cause of mortality and morbidity, and hence accurate and rapid diagnosis of stroke is valuable. Retinal fundus imaging reveals the known markers of elevated stroke risk in the eyes, which are retinal venular…

Image and Video Processing · Electrical Eng. & Systems 2025-02-04 Aysen Degerli , Mika Hilvo , Juha Pajula , Petri Huhtinen , Pekka Jäkälä

Diabetes-related retinal conditions can be detected by examining the posterior of the eye. By contrast, examining the anterior of the eye can reveal conditions affecting the front of the eye, such as changes to the eyelids, cornea, or…

Diabetic retinopathy (DR) is a significant cause of vision impairment, emphasizing the critical need for early detection and timely intervention to avert visual deterioration. Diagnosing DR is inherently complex, as it necessitates the…

Image and Video Processing · Electrical Eng. & Systems 2024-01-26 Mohamed R. Shoaib , Heba M. Emara , Jun Zhao , Walid El-Shafai , Naglaa F. Soliman , Ahmed S. Mubarak , Osama A. Omer , Fathi E. Abd El-Samie , Hamada Esmaiel

Intracranial aneurysms (IAs) are abnormal dilations of cerebral blood vessels that, if ruptured, can lead to life-threatening consequences. However, their small size and soft contrast in radiological scans often make it difficult to perform…

Image and Video Processing · Electrical Eng. & Systems 2025-08-04 Erin Rainville , Amirhossein Rasoulian , Hassan Rivaz , Yiming Xiao

Automatic classification of diabetic retinopathy from retinal images has been widely studied using deep neural networks with impressive results. However, there is a clinical need for estimation of the uncertainty in the classifications, a…

Computer Vision and Pattern Recognition · Computer Science 2022-02-03 Joel Jaskari , Jaakko Sahlsten , Theodoros Damoulas , Jeremias Knoblauch , Simo Särkkä , Leo Kärkkäinen , Kustaa Hietala , Kimmo Kaski

Though deep learning has shown successful performance in classifying the label and severity stage of certain disease, most of them give few evidence on how to make prediction. Here, we propose to exploit the interpretability of deep…

Computer Vision and Pattern Recognition · Computer Science 2020-03-16 Yuhao Niu , Lin Gu , Feng Lu , Feifan Lv , Zongji Wang , Imari Sato , Zijian Zhang , Yangyan Xiao , Xunzhang Dai , Tingting Cheng

In assessing the severity of age-related macular degeneration (AMD), the Age-Related Eye Disease Study (AREDS) Simplified Severity Scale predicts the risk of progression to late AMD. However, its manual use requires the time-consuming…

Computer Vision and Pattern Recognition · Computer Science 2019-01-29 Yifan Peng , Shazia Dharssi , Qingyu Chen , Tiarnan D. Keenan , Elvira Agrón , Wai T. Wong , Emily Y. Chew , Zhiyong Lu

Diabetic retinopathy (DR) is the primary cause of vision loss among grownup people around the world. In four out of five cases having diabetes for a prolonged period leads to DR. If detected early, more than 90 percent of the new DR…

Computer Vision and Pattern Recognition · Computer Science 2020-06-16 Niloy Sikder , Md. Sanaullah Chowdhury , Abu Shamim Mohammad Arif , Abdullah-Al Nahid