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A differential equations model is developed for the 2014 Ebola epidemics in Sierra Leone, Liberia, and Guinea. The model describes the dynamic interactions of the susceptible and infected populations of these countries. The model…

Populations and Evolution · Quantitative Biology 2014-10-23 Cameron Browne , Xi Huo , Pierre Magal , Moussa Seydi , Ousmanne Seydi , Glenn Webb

An Ebola outbreak of unparalleled size is currently affecting several countries in West Africa, and international efforts to control the outbreak are underway. However, the efficacy of these interventions, and their likely impact on an…

Populations and Evolution · Quantitative Biology 2014-09-23 Caitlin M. Rivers , Eric T. Lofgren , Madhav Marathe , Stephen Eubank , Bryan L. Lewis

Despite improved control measures, Ebola remains a serious public health risk in African regions where recurrent outbreaks have been observed since the initial epidemic in 1976. Using epidemic modeling and data from two well-documented…

Other Quantitative Biology · Quantitative Biology 2007-05-23 Gerardo Chowell , Nick W. Hengartner , Carlos Castillo-Chavez , Paul W. Fenimore , J. M. Hyman

Ebola virus is one of the most virulent pathogens for humans. We present a mathematical description of different Susceptible-Exposed-Infectious-Recovered (SEIR) models. By using mathematical modeling and analysis, the latest major outbreak…

Populations and Evolution · Quantitative Biology 2017-08-01 Amira Rachah , Delfim F. M. Torres

We consider an SEIR epidemic model on a network also allowing random contacts, where recovered individuals could either recover naturally or be diagnosed. Upon diagnosis, manual contact tracing is triggered such that each infected network…

Physics and Society · Physics 2024-06-06 Dongni Zhang , Tom Britton

Much effort has been directed towards using mathematical models to understand and predict contagious disease, in particular Ebola outbreaks. Classical SIR (susceptible-infected-recovered) compartmental models capture well the dynamics of…

Populations and Evolution · Quantitative Biology 2015-12-22 Anca Radulescu , Joanna Herron

The 2014 Ebola outbreak in west Africa raised many questions about the control of infectious disease in an increasingly connected global society. Limited availability of contact information made contact tracing difficult or impractical in…

Physics and Society · Physics 2016-03-09 Vincent Wong , Daniel Cooney , Yaneer Bar-Yam

We present a mathematical analysis of the early detection of Ebola virus. The propagation of the virus is analysed by using a Susceptible, Infected, Recovered (SIR) model. In order to provide useful predictions about the potential…

Populations and Evolution · Quantitative Biology 2016-05-24 Amira Rachah , Delfim F. M. Torres

In this paper, we have studied epidemiological models for Ebola infection using nonlinear ordinary differential equations and optimal control theory. We considered optimal control analysis of SIR and SEIR models for the deadly Ebola…

Dynamical Systems · Mathematics 2019-08-23 E. Okyere , J. D. Ankamah , A. K. Hunkpe , D. Mensah

A modified, deterministic SEIR model is developed for the 2014 Ebola epidemic occurring in the West African nations of Guinea, Liberia, and Sierra Leone. The model describes the dynamical interaction of susceptible and infected populations,…

Populations and Evolution · Quantitative Biology 2016-11-22 Paul Diaz , Paul Constantine , Kelsey Kalmbach , Eric Jones , Stephen Pankavich

Contacts between people are the absolute drivers of contagious respiratory infections. For this reason, limiting and tracking contacts is a key strategy for the control of the COVID-19 epidemic. Digital contact tracing has been proposed as…

Computers and Society · Computer Science 2022-12-01 Chiara Boldrini , Andrea Passarella , Marco Conti

The data for the Ebola outbreak that occurred in 2014-2016 in three countries of West Africa are analysed within a common framework. The analysis is made using the results of an agent based Susceptible-Infected-Removed (SIR) model on a…

Physics and Society · Physics 2017-02-02 Abdul Khaleque , Parongama Sen

This paper is concerned with a stochastic model for the spread of an SEIR (susceptible -> exposed (=latent) -> infective -> removed) epidemic with a contact tracing scheme, in which removed individuals may name some of their infectious…

Probability · Mathematics 2015-12-08 Frank G Ball , Edward S Knock , Philip D O'Neill

The Ebola Virus Disease (EVD) can persist in some body fluids after clinical recovery. In Guinea and the Democratic Republic of the Congo, there are well-documented cases of EVD reemergence that were associated with previous outbreaks. In…

Populations and Evolution · Quantitative Biology 2023-06-06 David Niyukuri , Kelly Joelle Gatore Sinigirira , Jean De Dieu Kwizera , Salma Omar Abd-Almageid Adam

Consider a Markovian SIR epidemic model in a homogeneous community. To this model we add a rate at which individuals are tested, and once an infectious individual tests positive it is isolated and each of their contacts are traced and…

Populations and Evolution · Quantitative Biology 2022-08-08 Dongni Zhang , Tom Britton

The spread of infectious diseases crucially depends on the pattern of contacts among individuals. Knowledge of these patterns is thus essential to inform models and computational efforts. Few empirical studies are however available that…

As an emergent infectious disease outbreak unfolds, public health response is reliant on information on key epidemiological quantities, such as transmission potential and serial interval. Increasingly, transmission models fit to incidence…

Populations and Evolution · Quantitative Biology 2015-06-29 Aaron A. King , Matthieu Domenech de Cellès , Felicia M. G. Magpantay , Pejman Rohani

A generalization of the standard susceptible-infectious-removed (SIR) stochastic model for epidemics in sparse random networks is introduced which incorporates contact tracing in addition to random screening. We propose a deterministic…

Adaptation and Self-Organizing Systems · Physics 2009-11-07 Ramon Huerta , Lev S. Tsimring

A stochastic epidemic model accounting for the effect of contact-tracing on the spread of an infectious disease is studied. Precisely, individuals identified as infected may contribute to detecting other infectious individuals by providing…

Probability · Mathematics 2009-03-28 Stéphan Clémençon , Viet Chi Tran , Hector De Arazoza

The most recent Ebola outbreak in West Africa highlighted critical weaknesses in the medical infrastructure of the affected countries, including effective diagnostics tools, sufficient isolation wards, and enough medical personnel. Here, we…

Populations and Evolution · Quantitative Biology 2015-11-13 Diego Chowell , Muntaser Safan , Carlos Castillo-Chavez
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