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The nucleotide sequence representation of DNA can be inadequate for resolving protein-DNA binding sites and regulatory substrates, such as those involved in gene expression and horizontal gene transfer. Considering that sequence-like…

Genomics · Quantitative Biology 2020-07-30 Jan Zrimec

We analyze the structure of DNA molecules of different organisms by using the additive Markov chain approach. Transforming nucleotide sequences into binary strings, we perform statistical analysis of the corresponding "texts". We develop…

Other Quantitative Biology · Quantitative Biology 2014-11-14 S. S. Melnik , O. V. Usatenko

Recent research efforts have shown that neural architectures can be effective in conventional information extraction tasks such as named entity recognition, yielding state-of-the-art results on standard newswire datasets. However, despite…

Computation and Language · Computer Science 2018-10-16 Bill Yuchen Lin , Wei Lu

Recent progress on salient object detection mainly aims at exploiting how to effectively integrate multi-scale convolutional features in convolutional neural networks (CNNs). Many popular methods impose deep supervision to perform…

Computer Vision and Pattern Recognition · Computer Science 2021-01-21 Yun Liu , Ming-Ming Cheng , Xinyu Zhang , Guang-Yu Nie , Meng Wang

In multi-domain proteins, the domains are connected by a flexible unstructured region called as protein domain linker. The accurate demarcation of these linkers holds a key to understanding of their biochemical and evolutionary attributes.…

Computational Engineering, Finance, and Science · Computer Science 2012-11-26 Vivekanand Samant , Arvind Hulgeri , Alfonso Valencia , Ashish V. Tendulkar

DNA sequence classification requires not only high predictive accuracy but also the ability to uncover latent site interactions, combinatorial regulation, and epistasis-like higher-order dependencies. Although the standard Transformer…

Machine Learning · Computer Science 2026-03-30 Zhixuan Cao , Yishu Xu , Xuang WU

Recent studies have introduced a new class of generative models for synthesizing implicit neural representations (INRs) that capture arbitrary continuous signals in various domains. These models opened the door for domain-agnostic…

Machine Learning · Computer Science 2024-03-21 Dogyun Park , Sihyeon Kim , Sojin Lee , Hyunwoo J. Kim

Gene annotation has traditionally required direct comparison of DNA sequences between an unknown gene and a database of known ones using string comparison methods. However, these methods do not provide useful information when a gene does…

Machine Learning · Computer Science 2019-09-17 James K. Senter , Taylor M. Royalty , Andrew D. Steen , Amir Sadovnik

Named entity recognition (NER) is a widely studied task in natural language processing. Recently, a growing number of studies have focused on the nested NER. The span-based methods, considering the entity recognition as a span…

Computation and Language · Computer Science 2021-06-22 Zeqi Tan , Yongliang Shen , Shuai Zhang , Weiming Lu , Yueting Zhuang

In this paper, we propose Describe-and-Dissect (DnD), a novel method to describe the roles of hidden neurons in vision networks. DnD utilizes recent advancements in multimodal deep learning to produce complex natural language descriptions,…

Computer Vision and Pattern Recognition · Computer Science 2025-02-20 Nicholas Bai , Rahul A. Iyer , Tuomas Oikarinen , Akshay Kulkarni , Tsui-Wei Weng

We present a new Deep Dictionary Learning and Coding Network (DDLCN) for image recognition tasks with limited data. The proposed DDLCN has most of the standard deep learning layers (e.g., input/output, pooling, fully connected, etc.), but…

Computer Vision and Pattern Recognition · Computer Science 2020-05-25 Hao Tang , Hong Liu , Wei Xiao , Nicu Sebe

Disentangled latent spaces usually have better semantic separability and geometrical properties, which leads to better interpretability and more controllable data generation. While this has been well investigated in Computer Vision, in…

Computation and Language · Computer Science 2024-06-12 Yingji Zhang , Danilo S. Carvalho , André Freitas

Large parallel gains in the development of both computational resources as well as sampling methods have now made it possible to simulate dissociation events in ligand-protein complexes with all--atom resolution. Such encouraging progress,…

We present a novel Dynamic Differentiable Reasoning (DDR) framework for jointly learning branching programs and the functions composing them; this resolves a significant nondifferentiability inhibiting recent dynamic architectures. We apply…

Computer Vision and Pattern Recognition · Computer Science 2018-04-02 Joseph Suarez , Justin Johnson , Fei-Fei Li

Solving partial differential equations (PDEs) on complex domains can present significant computational challenges. The Diffuse Domain Method (DDM) is an alternative that reformulates the partial differential equations on a larger, simpler…

Numerical Analysis · Mathematics 2025-07-24 Luke Benfield , Andreas Dedner

Deep neural networks (DNNs) have made breakthroughs in various fields including image recognition and language processing. DNNs execute hundreds of millions of multiply-and-accumulate (MAC) operations. To efficiently accelerate such…

Systems and Control · Electrical Eng. & Systems 2024-07-08 Amro Eldebiky , Grace Li Zhang , Xunzhao Yin , Cheng Zhuo , Ing-Chao Lin , Ulf Schlichtmann , Bing Li

Domain generation algorithms (DGAs) are frequently employed by malware to generate domains used for connecting to command-and-control (C2) servers. Recent work in DGA detection leveraged deep learning architectures like convolutional neural…

Cryptography and Security · Computer Science 2019-01-29 Joewie J. Koh , Barton Rhodes

Recent advances in next-generation sequencing technologies have facilitated the use of deoxyribonucleic acid (DNA) as a novel covert channels in steganography. There are various methods that exist in other domains to detect hidden messages…

Machine Learning · Computer Science 2018-10-08 Ho Bae , Byunghan Lee , Sunyoung Kwon , Sungroh Yoon

The alignment of biological sequences such as DNA, RNA, and proteins, is one of the basic tools that allow to detect evolutionary patterns, as well as functional/structural characterizations between homologous sequences in different…

Quantitative Methods · Quantitative Biology 2023-05-01 Louise Budzynski , Andrea Pagnani

Following Poland and Scheraga, we consider a simplified model for the denaturation transition of DNA. The two strands are modeled as interacting polymer chains. The attractive interactions, which mimic the pairing between the four bases,…

Soft Condensed Matter · Physics 2009-11-07 T. Garel , C. Monthus , H. Orland