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Biomolecular networks have already found great utility in characterizing complex biological systems arising from pair-wise interactions amongst biomolecules. Here, we review how graph theoretical approaches can be applied not only for a…

Molecular Networks · Quantitative Biology 2018-12-03 Heeralal Janwa , Steven E. Massey , Julian Velev , Bud Mishra

Genetic regulatory networks are defined by their topology and by a multitude of continuously adjustable parameters. Here we present a class of simple models within which the relative importance of topology vs. interaction strengths becomes…

Molecular Networks · Quantitative Biology 2013-08-02 Mikhail Tikhonov , William Bialek

Complex networks describe a wide range of systems in nature and society, much quoted examples including the cell, a network of chemicals linked by chemical reactions, or the Internet, a network of routers and computers connected by physical…

Statistical Mechanics · Physics 2016-08-31 Reka Albert , Albert-Laszlo Barabasi

The recent discovery of universal principles underlying many complex networks occurring across a wide range of length scales in the biological world has spurred physicists in trying to understand such features using techniques from…

Biological Physics · Physics 2015-05-13 Sitabhra Sinha

In this review, we give an introduction to the structural and functional properties of the biological networks. We focus on three major themes: topology of complex biological networks like the metabolic and protein-protein interaction…

Condensed Matter · Physics 2007-05-23 Indrani Bose

The interplay between topology and dynamics in complex networks is a fundamental but widely unexplored problem. Here, we study this phenomenon on a prototype model in which the network is shaped by a dynamical variable. We couple the…

Statistical Mechanics · Physics 2008-06-13 Diego Garlaschelli , Andrea Capocci , Guido Caldarelli

Understanding the origins of complexity is a fundamental challenge with implications for biological and technological systems. Network theory emerges as a powerful tool to model complex systems. Networks are an intuitive framework to…

Disordered Systems and Neural Networks · Physics 2024-10-22 Blai Vidiella , Salva Duran-Nebreda , Sergi Valverde

We explore the interplay between the topological relevance of a neuron and its dynamical traces in experimental cultured neuronal networks. We monitor the growth and development of these networks to characterise the evolution of their…

Adaptation and Self-Organizing Systems · Physics 2023-07-14 A. Tlaie , L. M. Ballesteros-Esteban , I. Leyva , I. Sendina-Nadal

Networks are important representations in computer science to communicate structural aspects of a given system of interacting components. The evolution of a network has several topological properties that can provide us information on the…

Social and Information Networks · Computer Science 2020-04-30 Joao Pita Costa , Tihana Galinac Grbac

Many complex systems can be described in terms of networks of interacting units. Recent studies have shown that a wide class of both natural and artificial nets display a surprisingly widespread feature: the presence of highly heterogeneous…

Disordered Systems and Neural Networks · Physics 2007-05-23 R. Ferrer i Cancho , R. V. Sole

We evolve network topology of an asymmetrically connected threshold network by a simple local rewiring rule: quiet nodes grow links, active nodes lose links. This leads to convergence of the average connectivity of the network towards the…

Disordered Systems and Neural Networks · Physics 2009-10-31 Stefan Bornholdt , Thimo Rohlf

Seeking effective neural networks is a critical and practical field in deep learning. Besides designing the depth, type of convolution, normalization, and nonlinearities, the topological connectivity of neural networks is also important.…

Computer Vision and Pattern Recognition · Computer Science 2020-08-20 Kun Yuan , Quanquan Li , Jing Shao , Junjie Yan

Network topology is a fundamental aspect of network science that allows us to gather insights into the complicated relational architectures of the world we inhabit. We provide a first specific study of neighbourhood degree sequences in…

Social and Information Networks · Computer Science 2019-06-11 Keith M. Smith

We apply a Bethe-Peierls approach to statistical-mechanics models defined on random networks of arbitrary degree distribution and arbitrary correlations between the degrees of neighboring vertices. Using the NP-hard optimization problem of…

Disordered Systems and Neural Networks · Physics 2009-11-07 Alexei Vazquez , Martin Weigt

A useful approach to the mathematical analysis of large-scale biological networks is based upon their decompositions into monotone dynamical systems. This paper deals with two computational problems associated to finding decompositions…

Molecular Networks · Quantitative Biology 2007-05-23 Bhaskar DasGupta , German Andres Enciso , Eduardo Sontag , Yi Zhang

One of the biggest needs in network science research is access to large realistic datasets. As data analytics methods permeate a range of diverse disciplines---e.g., computational epidemiology, sustainability, social media analytics,…

Social and Information Networks · Computer Science 2017-05-25 Malay Chakrabarti , Lenwood Heath , Naren Ramakrishnan

We present an analysis of the topologies of a class of networks which are optimal in terms of the requirements of having as short a route as possible between any two nodes while yet keeping the congestion in the network as low as possible.…

Statistical Mechanics · Physics 2009-11-10 Vittoria Colizza , Jayanth R. Banavar , Amos Maritan , Andrea Rinaldo

In this paper, we study instances of complex neural networks, i.e. neural netwo rks with complex topologies. We use Self-Organizing Map neural networks whose n eighbourhood relationships are defined by a complex network, to classify handwr…

Neural and Evolutionary Computing · Computer Science 2007-10-02 Fei Jiang , Hugues Berry , Marc Schoenauer

Networked structure emerged from a wide range of fields such as biological systems, World Wide Web and technological infrastructure. A deeply insight into the topological complexity of these networks has been gained. Some works start to pay…

Physics and Society · Physics 2012-02-03 Jiang Xiongfei

Recent genomic and bioinformatic advances have motivated the development of numerous random network models purporting to describe graphs of biological, technological, and sociological origin. The success of a model has been evaluated by how…

Molecular Networks · Quantitative Biology 2007-05-23 Manuel Middendorf , Etay Ziv , Carter Adams , Jen Hom , Robin Koytcheff , Chaya Levovitz , Gregory Woods , Linda Chen , Chris Wiggins
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