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One of the most common pitfalls often found in high dimensional biological data sets are correlations between the features. This may lead to statistical and machine learning methodologies overvaluing or undervaluing these correlated…

Machine Learning · Computer Science 2021-11-18 Troy Maaslandand , João Pereira , Diogo Bastos , Marcus de Goffau , Max Nieuwdorp , Aeilko H. Zwinderman , Evgeni Levin

The problem of inferring pair-wise and higher-order interactions in complex systems involving large numbers of interacting variables, from observational data, is fundamental to many fields. Known to the statistical physics community as the…

Methodology · Statistics 2021-01-01 Sjoerd Viktor Beentjes , Ava Khamseh

Predicting protein-protein interactions from sequences is an important goal of computational biology. Various sources of information can be used to this end. Starting from the sequences of two interacting protein families, one can use…

Biomolecules · Quantitative Biology 2023-04-26 Carlos A. Gandarilla-Perez , Sergio Pinilla , Anne-Florence Bitbol , Martin Weigt

Despite growing interest in probabilistic modeling approaches and availability of learning tools, people with no or less statistical background feel hesitant to use them. There is need for tools for communicating probabilistic models to…

Human-Computer Interaction · Computer Science 2022-02-22 Evdoxia Taka , Sebastian Stein , John H. Williamson

In general, it is difficult to evaluate measurement errors when the initial and final conditions of the measurement make it impossible to identify the correct value of the target observable. Ozawa proposed a solution based on the operator…

Quantum Physics · Physics 2016-03-09 Masataka Iinuma , Yutaro Suzuki , Taiki Nii , Ryuji Kinoshita , Holger F. Hofmann

Many scientific questions in biomedical, environmental, and psychological research involve understanding the effects of multiple factors on outcomes. While factorial experiments are ideal for this purpose, randomized controlled treatment…

Methodology · Statistics 2025-12-03 Ruoqi Yu , Peng Ding

This article deals with the analysis of high dimensional data that come from multiple sources (experiments) and thus have different possibly correlated responses, but share the same set of predictors. The measurements of the predictors may…

Methodology · Statistics 2020-07-01 Guorong Dai , Ursula U. Müller , Raymond J. Carroll

This paper studies experimental designs for estimation and inference on policies with spillover effects. Units are organized into a finite number of large clusters and interact in unknown ways within each cluster. First, we introduce a…

Econometrics · Economics 2024-05-06 Davide Viviano , Jess Rudder

In paired experiments, participants are grouped into pairs with similar characteristics, and one observation from each pair is randomly assigned to treatment. Because of both the pairing and the randomization, the treatment and control…

Applications · Statistics 2019-05-22 Edward Wu , Johann A. Gagnon-Bartsch

In this paper, we present a new way of matching in observational studies that overcomes three limitations of existing matching approaches. First, it directly balances covariates with multi-valued treatments without requiring the generalized…

Applications · Statistics 2019-07-11 Magdalena Bennett , Juan Pablo Vielma , Jose R. Zubizarreta

We consider a setting in which we have a treatment and a large number of covariates for a set of observations, and wish to model their relationship with an outcome of interest. We propose a simple method for modeling interactions between…

Methodology · Statistics 2012-12-14 Lu Tian , Ash Alizadeh , Andrew Gentles , Robert Tibshirani

Interactions are patterns between several attributes in data that cannot be inferred from any subset of these attributes. While mutual information is a well-established approach to evaluating the interactions between two attributes, we…

Artificial Intelligence · Computer Science 2007-05-23 Aleks Jakulin , Ivan Bratko

The robust detection of statistical dependencies between the components of a complex system is a key step in gaining a network-based understanding of the system. Because of their simplicity and low computation cost, pairwise statistics are…

Statistics Theory · Mathematics 2019-08-01 Antoine Messager , Nicos Georgiou , Luc Berthouze

Protein interactions are important in a broad range of biological processes. Traditionally, computational methods have been developed to automatically predict protein interface from hand-crafted features. Recent approaches employ deep…

Machine Learning · Computer Science 2020-07-21 Yi Liu , Hao Yuan , Lei Cai , Shuiwang Ji

The pairwise winning indices, computed in the Stochastic Multicriteria Acceptability Analysis, give the probability with which an alternative is preferred to another taking into account all the instances of the assumed preference model…

Optimization and Control · Mathematics 2022-03-29 Sally Giuseppe Arcidiacono , Salvatore Corrente , Salvatore Greco

Measurements are crucial in quantum mechanics, in fundamental research as well as in applicative fields like quantum metrology, quantum-enhanced measurements and other quantum technologies. In the recent years, weak-interaction-based…

Nonlocality plays a fundamental role in quantum information science. Recently, it has been theoretically predicted and experimentally demonstrated that the nonlocality of an entangled pair may be shared among multiple observers using weak…

Quantum Physics · Physics 2020-10-06 Tianfeng Feng , Changliang Ren , Yuling Tian , Maolin Luo , Haofei Shi , Jingling Chen , Xiaoqi Zhou

Numerical predictions of quantities of interest measured within physical systems rely on the use of mathematical models that should be validated, or at best, not invalidated. Model validation usually involves the comparison of experimental…

Computational Engineering, Finance, and Science · Computer Science 2023-07-19 Antonin Paquette-Rufiange , Serge Prudhomme , Marc Laforest

We address estimation of intervention effects in experimental designs in which (a) interventions are assigned at the cluster level; (b) clusters are selected to form pairs, matched on observed characteristics; and (c) intervention is…

Methodology · Statistics 2014-11-24 Zhenke Wu , Constantine E. Frangakis , Thomas A. Louis , Daniel O. Scharfstein

High-dimensional systems are an important frontier for photonic quantum correlation experiments. These correlation tests commonly prescribe measurements with many possible outcomes but they are often implemented through many individual…

Quantum Physics · Physics 2025-05-01 Armin Tavakoli , Roope Uola , Jef Pauwels
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