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The simplest, most common paired samples consist of observations from two populations, with each observed response from one population corresponding to an observed response from the other population at the same value of an ordinal…

Methodology · Statistics 2024-04-09 Isabel Kloumann , Hannah Korevaar , Chris McConnell , Mark Tygert , Jessica Zhao

Detection of interactions between treatment effects and patient descriptors in clinical trials is critical for optimizing the drug development process. The increasing volume of data accumulated in clinical trials provides a unique…

Applications · Statistics 2017-12-25 Baptiste Goujaud , Eric W. Tramel , Pierre Courtiol , Mikhail Zaslavskiy , Gilles Wainrib

It is shown how by not losing information on higher order interactions, optimal paired comparison designs involving alternatives of either full or partial profiles to reduce information overload as frequently encountered in applications can…

Methodology · Statistics 2019-12-04 Eric Nyarko

Uncoupled regression is the problem to learn a model from unlabeled data and the set of target values while the correspondence between them is unknown. Such a situation arises in predicting anonymized targets that involve sensitive…

Machine Learning · Computer Science 2019-06-04 Liyuan Xu , Junya Honda , Gang Niu , Masashi Sugiyama

Most popular strategies to capture subjective judgments from humans involve the construction of a unidimensional relative measurement scale, representing order preferences or judgments about a set of objects or conditions. This information…

Applications · Statistics 2017-12-18 Maria Perez-Ortiz , Rafal K. Mantiuk

The problem of testing changes in covariance has received increasing attention in recent years, especially in the context of high-dimensional testing. A number of approaches have been proposed, all limited to the two-sample problem and…

Methodology · Statistics 2016-09-06 Yi-Hui Zhou

In many contexts it is extremely costly to perform enough high quality experimental measurements to accurately parameterize a predictive quantitative model. However, it is often much easier to carry out large numbers of experiments that…

Data Analysis, Statistics and Probability · Physics 2017-11-22 Alpha A. Lee , Michael P. Brenner , Lucy J. Colwell

We aim to create the highest possible quality of treatment-control matches for categorical data in the potential outcomes framework. Matching methods are heavily used in the social sciences due to their interpretability, but most matching…

Machine Learning · Statistics 2019-06-11 Yameng Liu , Aw Dieng , Sudeepa Roy , Cynthia Rudin , Alexander Volfovsky

Generating paired sequences with maximal compatibility from a given set is one of the most important challenges in various applications, including information and communication technologies. However, the number of possible pairings explodes…

Data Structures and Algorithms · Computer Science 2022-05-10 Naoki Fujita , Nicolas Chauvet , Andre Roehm , Ryoichi Horisaki , Aohan Li , Mikio Hasegawa , Makoto Naruse

Quantifying the complexity of systems consisting of many interacting parts has been an important challenge in the field of complex systems in both abstract and applied contexts. One approach, the complexity profile, is a measure of the…

Pattern Formation and Solitons · Physics 2013-06-03 Yavni Bar-Yam , Dion Harmon , Yaneer Bar-Yam

Using mathematical models to assist in the interpretation of experiments is becoming increasingly important in research across applied mathematics, and in particular in biology and ecology. In this context, accurate parameter estimation is…

Statistics Theory · Mathematics 2025-04-29 Jie Qi , Ruth E. Baker

Background:Typically, proteins perform key biological functions by interacting with each other. As a consequence, predicting which protein pairs interact is a fundamental problem. Experimental methods are slow, expensive, and may be error…

Biomolecules · Quantitative Biology 2022-02-08 Leonardo Martini , Adriano Fazzone , Luca Becchetti

Linear mixed-effects models are widely used in analyzing clustered or repeated measures data. We propose a quasi-likelihood approach for estimation and inference of the unknown parameters in linear mixed-effects models with high-dimensional…

Methodology · Statistics 2021-03-10 Sai Li , Tony T. Cai , Hongzhe Li

We propose a new method to estimate causal effects from nonexperimental data. Each pair of sample units is first associated with a stochastic 'treatment' - differences in factors between units - and an effect - a resultant outcome…

Methodology · Statistics 2022-11-08 Andre F. Ribeiro , Frank Neffke , Ricardo Hausmann

Statistical matching is an effective method for estimating causal effects in which treated units are paired with control units with ``similar'' values of confounding covariates prior to performing estimation. In this way, matching helps…

Methodology · Statistics 2023-09-13 Sanjeewani Weerasingha , Michael J. Higgins

The origin of non-classical correlations is difficult to identify since the uncertainty principle requires that information obtained about one observable invariably results in the disturbance of any other non-commuting observable. Here,…

Quantum Physics · Physics 2014-07-01 Holger F. Hofmann

Bipartite experiments arise in various fields, in which the treatments are randomized over one set of units, while the outcomes are measured over another separate set of units. However, existing methods often rely on strong model…

Methodology · Statistics 2025-04-16 Sizhu Lu , Lei Shi , Yue Fang , Wenxin Zhang , Peng Ding

We investigate the estimation of a small interaction parameter from the outcomes of weak quantum measurements implemented by the interaction. The relation of weak values and sensitivity is explained and the different contributions of…

Quantum Physics · Physics 2012-10-23 Holger F. Hofmann , Michael E. Goggin , Marcelo P. Almeida , Marco Barbieri

It is common to conduct causal inference in matched observational studies by proceeding as though treatment assignments within matched sets are assigned uniformly at random and using this distribution as the basis for inference. This…

Methodology · Statistics 2023-11-14 Samuel D. Pimentel , Yaxuan Huang

The design of experiments in psychology can often be summarized to participants reacting to stimuli. For such an experiment, the mixed effects model with crossed random effects is usually the appropriate tool to analyse the data because it…

Methodology · Statistics 2020-10-19 Jaromil Frossard , Olivier Renaud