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Super-resolution localization microscopy is based on determining the positions of individual fluorescent markers in a sample. The major challenge in reaching an ever higher localization precision lies in the limited number of collected…

Optics · Physics 2020-08-05 Daniel Böning , Franz-Ferdinand Wieser , Vahid Sandoghdar

In this paper, we show that it is possible to overcome one of the fundamental limitations of super-resolution microscopy techniques: the necessity to be in an \emph{optically homogeneous} environment. Using recent modal approximation…

Analysis of PDEs · Mathematics 2022-07-14 Lorenzo Baldassari , Alice L. Vanel , Pierre Millien

In single molecule localisation super-resolution microscopy the need for repeated image capture limits the imaging speed, while the size of fluorescence probes limits the possible theoretical localisation resolution. Here, we demonstrated a…

A standard paradigm of localization microscopy involves extension from two to three dimensions by engineering information into emitter images, and approximation of errors resulting from the field dependence of optical aberrations. We invert…

This paper proposes a method for detecting multiple scatterers (targets) in the elevation direction for synthetic aperture radar (SAR) tomography. The proposed method can resolve closely spaced targets through a twostep procedure. In the…

Information Theory · Computer Science 2022-04-11 Ahmad Naghavi , Mohammad Sadegh Fazel , Mojtaba Beheshti , Ehsan Yazdian

We consider simultaneously identifying the membership and locations of point sources that are convolved with different low-pass point spread functions, from the observation of their superpositions. This problem arises in three-dimensional…

Information Theory · Computer Science 2015-04-24 Yuanxin Li , Yuejie Chi

Single Molecule Localization Microscopy (SMLM) enables the acquisition of high-resolution images by alternating between activation of a sparse subset of fluorescent molecules present in a sample and localization. In this work, the…

Image and Video Processing · Electrical Eng. & Systems 2018-12-17 Arne Bechensteen , Laure Blanc-Féraud , Gilles Aubert

Ultrasound localization microscopy has enabled super-resolution vascular imaging through precise localization of individual ultrasound contrast agents (microbubbles) across numerous imaging frames. However, analysis of high-density regions…

Signal Processing · Electrical Eng. & Systems 2018-12-14 Ruud J. G. van Sloun , Oren Solomon , Matthew Bruce , Zin Z. Khaing , Hessel Wijkstra , Yonina C. Eldar , Massimo Mischi

With more devices competing for limited spectrum, dynamic spectrum sharing is increasingly vulnerable to interference from unauthorized emitters. This motivates fast detection and localization of these emitters using low-cost, distributed…

Signal Processing · Electrical Eng. & Systems 2025-12-02 H. Nazim Bicer

The localization of directional RF emitters presents significant challenges for electronic warfare applications. Traditional localization methods, designed for omnidirectional emitters, experience degraded performance when applied to…

Signal Processing · Electrical Eng. & Systems 2025-10-30 Fraser Williams , Akila Pemasiri , Dhammika Jayalath , Terry Martin , Clinton Fookes

This paper provides a theoretical analysis of diffraction-limited superresolution, demonstrating that arbitrarily close point sources can be resolved in ideal situations. Precisely, we assume that the incoming signal is a linear combination…

Optimization and Control · Mathematics 2015-08-14 Geoffrey Schiebinger , Elina Robeva , Benjamin Recht

Various techniques have been developed to measure the 2D and 3D positions and 2D and 3D orientations of fluorescent molecules with improved precision over standard epifluorescence microscopes. Due to the challenging signal-to-background…

Optics · Physics 2021-02-02 Oumeng Zhang , Matthew D. Lew

When a single molecule is detected in a wide-field microscope, the image approximates the point spread function of the system. However, as the distribution of molecules becomes denser and their images begin to coincide, existing solutions…

Optics · Physics 2013-09-02 Anthony Barsic , Ginni Grover , Rafael Piestun

Emitter localization is widely applied in the military and civilian _elds. In this paper, we tackle the problem of position estimation for multiple stationary emitters using Doppler frequency shifts and angles by moving receivers. The…

Signal Processing · Electrical Eng. & Systems 2021-12-07 Ziqiang Wang , Yimao Sun , Qun Wan , Lei Xie , Ning Liu

This paper focuses on the problem of localising a transmitting mobile station (MS) using multiple cooperative base stations (BSs). There are two technical difficulties: one is the data association between intermediate parameters and…

Signal Processing · Electrical Eng. & Systems 2019-11-21 Hengyan Liu , Wei Dai , Yuan Shen

Detectors inherently capable of resolving photon numbers have undergone a significant development recently, and this is expected to affect multiplexed periodic single-photon sources where such detectors can find their applications. We…

Quantum Physics · Physics 2020-07-29 Ferenc Bodog , Matyas Mechler , Matyas Koniorczyk , Peter Adam

Assume that a source emits a signal in $3$-dimensional space at an unknown time, which is received by at least~$5$ sensors. In almost all cases the emission time and source position can be worked out uniquely from the knowledge of the times…

Commutative Algebra · Mathematics 2022-07-12 Mireille Boutin , Gregor Kemper

Resolving sources beyond the diffraction limit is important in imaging, communications, and metrology. Current image-based methods of super-resolution require phase information (either of the source points or an added filter) and perfect…

Optics · Physics 2025-12-16 S. A. Wadood , Shaurya Aarav , Kevin Liang , Jason W Fleischer

An image super-resolution method from multiple observation of low-resolution images is proposed. The method is based on sub-pixel accuracy block matching for estimating relative displacements of observed images, and sparse signal…

Computer Vision and Pattern Recognition · Computer Science 2014-02-18 Toshiyuki Kato , Hideitsu Hino , Noboru Murata

In this paper we present a new localization method SMS-LORETA (Simultaneous Multiple Sources- Low Resolution Brain Electromagnetic Tomography), capable to locate efficiently multiple simultaneous sources. The new method overcomes some of…

Quantitative Methods · Quantitative Biology 2011-01-07 Avni Pllana , Herbert Bauer
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