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Background: In settings where proof-of-principle trials have succeeded but the effectiveness of different forms of implementation remains uncertain, trials that not only generate information about intervention effects but also provide…

Quantitative Methods · Quantitative Biology 2017-05-16 Guy Harling , Rui Wang , Jukka-Pekka Onnela , Victor De Gruttola

How should a network experiment be designed to achieve high statistical power? Ex- perimental treatments on networks may spread. Randomizing assignment of treatment to nodes enhances learning about the counterfactual causal effects of a…

Methodology · Statistics 2018-04-02 Jake Bowers , Bruce A. Desmarais , Mark Frederickson , Nahomi Ichino , Hsuan-Wei Lee , Simi Wang

The spread of an infectious disease can be promoted by previous infections with other pathogens. This cooperative effect can give rise to violent outbreaks, reflecting the presence of an abrupt epidemic transition. As for other diffusive…

Physics and Society · Physics 2019-02-06 Peng-Bi Cui , Francesca Colaiori , Claudio Castellano

The presence of interference, where the outcome of an individual may depend on the treatment assignment and behavior of neighboring nodes, can lead to biased causal effect estimation. Current approaches to network experiment design focus on…

Machine Learning · Computer Science 2024-05-22 Zahra Fatemi , Jean Pouget-Abadie , Elena Zheleva

Background: When planning a cluster randomized trial, evaluators often have access to an enumerated cohort representing the target population of clusters. Practicalities of conducting the trial, such as the need to oversample clusters with…

Methodology · Statistics 2024-09-19 Sarah E. Robertson , Jon A. Steingrimsson , Issa J. Dahabreh

The social networks that infectious diseases spread along are typically clustered. Because of the close relation between percolation and epidemic spread, the behavior of percolation in such networks gives insight into infectious disease…

Quantitative Methods · Quantitative Biology 2009-05-14 Joel C Miller

Pragmatic trials evaluating health care interventions often adopt cluster randomization due to scientific or logistical considerations. Previous reviews have shown that co-primary endpoints are common in pragmatic trials but infrequently…

Methodology · Statistics 2022-05-03 Siyun Yang , Mirjam Moerbeek , Monica Taljaard , Fan Li

Networks of person-person contacts form the substrate along which infectious diseases spread. Most network-based studies of the spread focus on the impact of variations in degree (the number of contacts an individual has). However, other…

Quantitative Methods · Quantitative Biology 2008-12-15 Joel C. Miller

In this article, we develop methods for sample size and power calculations in four-level intervention studies when intervention assignment is carried out at any level, with a particular focus on cluster randomized trials (CRTs). CRTs…

Methodology · Statistics 2022-09-07 Xueqi Wang , Elizabeth L. Turner , John S. Preisser , Fan Li

How does social network structure amplify or stifle behavior diffusion? Existing theory suggests that when social reinforcement makes the adoption of behavior more likely, it should spread more -- both farther and faster -- on clustered…

Social and Information Networks · Computer Science 2025-07-11 Allison Wan , Christoph Riedl , David Lazer

This paper studies inference in cluster randomized trials where treatment status is determined according to a "matched pairs" design. Here, by a cluster randomized experiment, we mean one in which treatment is assigned at the level of the…

Econometrics · Economics 2025-08-14 Yuehao Bai , Jizhou Liu , Azeem M. Shaikh , Max Tabord-Meehan

Recent studies in network science and control have shown a meaningful relationship between the epidemic processes (e.g., COVID-19 spread) and some network properties. This paper studies how such network properties, namely clustering…

Social and Information Networks · Computer Science 2023-03-17 Mohammadreza Doostmohammadian , Hamid R. Rabiee

We review and conceptualize recent advances in causal inference under network interference, drawing on a complex and diverse body of work that ranges from causal inference, statistical network analysis, economics, the health sciences, and…

Methodology · Statistics 2025-08-12 Subhankar Bhadra , Michael Schweinberger

Randomized experiments are widely used to estimate the causal effects of a proposed treatment in many areas of science, from medicine and healthcare to the physical and biological sciences, from the social sciences to engineering, to public…

Methodology · Statistics 2022-11-30 Christina Lee Yu , Edoardo M Airoldi , Christian Borgs , Jennifer T Chayes

Estimation of social influence in networks can be substantially biased in observational studies due to homophily and network correlation in exposure to exogenous events. Randomized experiments, in which the researcher intervenes in the…

Social and Information Networks · Computer Science 2017-09-28 Sean J. Taylor , Dean Eckles

Individuals involved in common group activities/settings -- e.g., college students that are enrolled in the same class and/or live in the same dorm -- are exposed to recurrent contacts of physical proximity. These contacts are known to…

Physics and Society · Physics 2024-10-22 Siddharth Patwardhan , Varun K. Rao , Santo Fortunato , Filippo Radicchi

There is a rich history of models for the interaction of a biological contagion like influenza with the spread of related information such as an influenza vaccination campaign. Recent work on the spread of interacting contagions on networks…

Physics and Society · Physics 2020-09-02 Laurent Hébert-Dufresne , Dina Mistry , Benjamin M. Althouse

Estimating the effects of interventions in networks is complicated when the units are interacting, such that the outcomes for one unit may depend on the treatment assignment and behavior of many or all other units (i.e., there is…

Methodology · Statistics 2014-08-15 Dean Eckles , Brian Karrer , Johan Ugander

Power-law behaviors are common in many disciplines, especially in network science. Real-world networks, like disease spreading among people, are more likely to be interconnected communities, and show richer power-law behaviors than isolated…

Physics and Society · Physics 2020-09-30 Jing Ma , Lucas D. Valdez , Lidia A. Braunstein

Contact tracing, the practice of isolating individuals who have been in contact with infected individuals, is an effective and practical way of containing disease spread. Here, we show that this strategy is particularly effective in the…

Physics and Society · Physics 2024-02-12 Abbas K. Rizi , Leah A. Keating , James P. Gleeson , David J. P. O'Sullivan , Mikko Kivelä
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