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The amount of information in the form of features and variables avail- able to machine learning algorithms is ever increasing. This can lead to classifiers that are prone to overfitting in high dimensions, high di- mensional models do not…

Machine Learning · Computer Science 2014-02-12 Aaron Karper

This paper concerns applications of genetic algorithms and genetic programming to tasks for which it is difficult to find a representation that does not map to a highly complex and discontinuous fitness landscape. In such cases the standard…

Neural and Evolutionary Computing · Computer Science 2016-05-06 Michal Gregor , Juraj Spalek

Likelihood-based, or explicit, deep generative models use neural networks to construct flexible high-dimensional densities. This formulation directly contradicts the manifold hypothesis, which states that observed data lies on a…

Machine Learning · Statistics 2022-11-30 Gabriel Loaiza-Ganem , Brendan Leigh Ross , Jesse C. Cresswell , Anthony L. Caterini

Resource constrained job scheduling is a hard combinatorial optimisation problem that originates in the mining industry. Off-the-shelf solvers cannot solve this problem satisfactorily in reasonable timeframes, while other solution methods…

Neural and Evolutionary Computing · Computer Science 2024-07-23 Su Nguyen , Dhananjay Thiruvady , Yuan Sun , Mengjie Zhang

Computer simulations of complex population genetic models are an essential tool for making sense of the large-scale datasets of multiple genome sequences from a single species that are becoming increasingly available. A widely used approach…

Populations and Evolution · Quantitative Biology 2026-04-23 Parul Johri , Fanny Pouyet , Brian Charlesworth

Neural networks and deep learning are changing the way that artificial intelligence is being done. Efficiently choosing a suitable network architecture and fine-tune its hyper-parameters for a specific dataset is a time-consuming task given…

Machine Learning · Computer Science 2019-05-16 David Laredo , Yulin Qin , Oliver Schütze , Jian-Qiao Sun

Optimization problems frequently appear in any scientific domain. Most of the times, the corresponding decision problem turns out to be NP-hard, and in these cases genetic algorithms are often used to obtain approximated solutions. However,…

Neural and Evolutionary Computing · Computer Science 2024-02-02 Alba Muñoz , Fernando Rubio

As computer scientists working in bioinformatics/computational biology, we often face the challenge of coming up with an algorithm to answer a biological question. This occurs in many areas, such as variant calling, alignment, and assembly.…

Data Structures and Algorithms · Computer Science 2018-01-04 Paul Medvedev

Plant breeding programs use data obtained from multi-environment selection experiments to produce improved varieties with the ultimate aim of maintaining high levels of genetic gain. Selection accuracy can be improved with the use of…

Methodology · Statistics 2026-05-13 Brian R Cullis , Alison B Smith , David GD Hughes , David Butler

Excessive reliance on validation performance during model selection can lead to validation overfitting (VO), where models appear effective during development but fail at test time. This issue is further amplified in low-data regimes and…

Neural and Evolutionary Computing · Computer Science 2026-03-13 Emmanuel Pintelas , Ioannis E. Livieris

From a model-building perspective, we propose a paradigm shift for fitting over-parameterized models. Philosophically, the mindset is to fit models to future observations rather than to the observed sample. Technically, given an imputation…

Methodology · Statistics 2024-12-09 Yiran Jiang , Chuanhai Liu

Despite tremendous progress, machine learning and deep learning still suffer from incomprehensible predictions. Incomprehensibility, however, is not an option for the use of (deep) reinforcement learning in the real world, as unpredictable…

Artificial Intelligence · Computer Science 2024-07-23 Manuel Eberhardinger , Florian Rupp , Johannes Maucher , Setareh Maghsudi

The overall aim of the software industry is to ensure delivery of high quality software to the end user. To ensure high quality software, it is required to test software. Testing ensures that software meets user specifications and…

Software Engineering · Computer Science 2014-11-06 Chayanika Sharma , Sangeeta Sabharwal , Ritu Sibal

In this article we provide a comprehensive review of the different evolutionary algorithm techniques used to address multimodal optimization problems, classifying them according to the nature of their approach. On the one hand there are…

Neural and Evolutionary Computing · Computer Science 2015-08-24 Noe Casas

Many modern machine learning models are trained to achieve zero or near-zero training error in order to obtain near-optimal (but non-zero) test error. This phenomenon of strong generalization performance for "overfitted" / interpolated…

Machine Learning · Statistics 2018-10-29 Mikhail Belkin , Daniel Hsu , Partha Mitra

Machine learning and deep learning have been celebrating many successes in the application to biological problems, especially in the domain of protein folding. Another equally complex and important question has received relatively little…

Machine Learning · Computer Science 2023-10-09 Lucie Bourguignon , Caroline Weis , Catherine R. Jutzeler , Michael Adamer

Fitting models to data is an important part of the practice of science. Advances in machine learning have made it possible to fit more -- and more complex -- models, but have also exacerbated a problem: when multiple models fit the data…

Methodology · Statistics 2025-10-27 Alexandre René , André Longtin

We study the problem of selecting limited features to observe such that models trained on them can perform well simultaneously across multiple subpopulations. This problem has applications in settings where collecting each feature is…

Machine Learning · Computer Science 2025-10-27 Maitreyi Swaroop , Tamar Krishnamurti , Bryan Wilder

The model selection procedure is usually a single-criterion decision making in which we select the model that maximizes a specific metric in a specific set, such as the Validation set performance. We claim this is very naive and can perform…

Machine Learning · Computer Science 2022-07-15 Felipe Costa Farias , Teresa Bernarda Ludermir , Carmelo José Albanez Bastos-Filho

In image-based reinforcement learning (RL), policies usually operate in two steps: first extracting lower-dimensional features from raw images (the "recognition" step), and then taking actions based on the extracted features (the "decision"…

Machine Learning · Computer Science 2025-04-04 Alihan Hüyük , Arndt Ryo Koblitz , Atefeh Mohajeri , Matthew Andrews