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Related papers: Optimal search in E.coli chemotaxis

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Bacteria can adjust their swimming behaviour in response to chemical variations, a phenomenon known as chemotaxis. This process is characterised by a drift velocity that depends non-linearly on the concentration of chemical species and its…

Fluid Dynamics · Physics 2026-05-07 Adam Gargasson , Julien Bouvard , Carine Douarche , Peter Mergaert , Harold Auradou

Escherichia coli has long been used as a model organism due to the extensive experimental characterization of its pathways and molecular components. Take chemotaxis as an example, which allows bacteria to sense and swim in response to…

Cell Behavior · Quantitative Biology 2015-12-09 Gabriele Micali , Robert G. Endres

A three-dimensional hydrodynamical model for a micro random walker is combined with the idea of chemotactic signaling network of E. coli. Diffusion exponents, orientational correlation functions and their dependence on the geometrical and…

Soft Condensed Matter · Physics 2014-10-02 H. Mohammady , B. Esckandariun , A. Najafi

In many situations, simply finding a target during a search is not enough. It is equally important to be able to return to that target repeatedly or to enable a larger community to locate and utilize it. While first passage time is commonly…

Soft Condensed Matter · Physics 2025-07-16 Vladimir Yu. Rudyak , Shahar Shinehorn , Yael Roichman

We confine a dense suspension of motile \textit{Escherichia coli} inside a spherical droplet in a water-in-oil emulsion, creating a "bacterially" propelled droplet. We show that droplets move in a persistent random walk, with a persistence…

Soft Condensed Matter · Physics 2019-12-10 Gabriel Ramos , Maria Luisa Cordero , Rodrigo Soto

A prime example of non-equilibrium or active environment is a biological cell. In order to understand in-vivo functioning of biomolecules such as proteins, chromatins, a description beyond equilibrium is absolutely necessary. In this…

Soft Condensed Matter · Physics 2019-03-27 Subhasish Chaki , Rajarshi Chakrabarti

In olfactory search an immobile target emits chemical molecules at constant rate. The molecules are transported by the medium which is assumed to be turbulent. Considering a searcher able to detect such chemical signals and whose motion…

Statistical Mechanics · Physics 2014-02-12 Juan Duque-Rodríguez , David Gómez-Ullate , Carlos Mejía-Monasterio

A random search of a partially absorbing target by a run-and-tumble particle in a confined one-dimensional space is investigated. We analytically obtain the mean searching time, which shows a non-monotonic behavior as a function of the…

Statistical Mechanics · Physics 2023-10-09 Euijin Jeon , Byeongguk Go , Yong Woon Kim

Bacteria commonly inhabit porous environments such as host tissues, soil, and marine sediments, where complex geometries constrain and redirect their motion. Although bacterial motility has been studied in porous media, the roles of cell…

Soft Condensed Matter · Physics 2025-12-22 David Gao , Zeyuan Wang , Mihika Jain , Arnold J. T. M. Mathijssen , Ran Tao

The run-and-tumble walk, consisting in randomly reoriented ballistic excursions, models phenomena ranging from gas kinetics to bacteria motility. We evaluate the mean time required for this walk to find a fixed target within a 2D or 3D…

Statistical Mechanics · Physics 2016-07-18 Jean-Francois Rupprecht , Olivier Bénichou , Raphael Voituriez

Models for chemotaxis are based on gradient sensing of individual organisms. The key contribution of Keller and Segel is showing that erratic movements of individuals may result in an accurate chemotaxis phenomenon as a group. In this paper…

Populations and Evolution · Quantitative Biology 2013-07-31 Changwook Yoon , Yong-Jung Kim

We study bacterial diffusion in disordered porous media. Interactions with obstacles, at unknown locations, make this problem challenging. We approach it by abstracting the environment to cell states with memoryless transitions. With this,…

Soft Condensed Matter · Physics 2023-12-29 Henry H. Mattingly

Run-and-tumble is a basic model of persistent motion and a motility strategy widespread in micro-organisms and individual cells. In many natural settings, movement occurs in the presence of confinement. While accumulation at the surface has…

Soft Condensed Matter · Physics 2024-04-12 T. Pietrangeli , C. Ybert , C. Cottin-Bizonne , F. Detcheverry

Bacterial motility, and in particular repulsion or attraction towards specific chemicals, has been a subject of investigation for over 100 years, resulting in detailed understanding of bacterial chemotaxis and the corresponding sensory…

Biological Physics · Physics 2022-06-08 Jerko Rosko , Vincent Martinez , Wilson Poon , Teuta Pilizota

Run-and-tumble is a common but vital strategy that bacteria employ to explore environment suffused with boundaries, as well as to escape from entrapment. In this study we reveal how this strategy and the resulting dynamical behavior can be…

Soft Condensed Matter · Physics 2025-01-30 Premkumar Leishangthem , Xuan Wang , Junan Chen , Shengqi Yang , Xinliang Xu

Escherichia coli is a motile bacterium that moves up a chemoattractant gradient by performing a biased random walk composed of alternating runs and tumbles. This paper presents calculations of the chemotactic drift velocity vd (the mean…

Quantitative Methods · Quantitative Biology 2008-04-16 J. T. Locsei , T. J. Pedley

Efficiency of search for randomly distributed targets is a prominent problem in many branches of the sciences. For the stochastic process of L\'evy walks, a specific range of optimal efficiencies was suggested under variation of search…

Statistical Mechanics · Physics 2021-06-11 S. Mohsen J. Khadem , Sabine H. L. Klapp , Rainer Klages

We study the crossing time statistic of diffusing point particles between the two ends of expanding and narrowing two-dimensional conical channels under a transverse external gravitational field. The theoretical expression for the mean…

Statistical Mechanics · Physics 2023-01-11 Ivan Pompa-Garcia , Rodrigo Castilla , Ralf Metzler , Leonardo Dagdug

Bacterial chemotactic sensing converts noisy chemical signals into running and tumbling. We analyze the static sensing limits of mixed Tar/Tsr chemoreceptor clusters in individual Escherichia coli cells using a heterogeneous…

Quantitative Methods · Quantitative Biology 2026-02-24 Ziyi Cui , Sarah Marzen

We study first-passage time problems for a diffusive particle with stochastic resetting with a finite rate $r$. The optimal search time is compared quantitatively with that of an effective equilibrium Langevin process with the same…

Statistical Mechanics · Physics 2015-06-12 Martin R. Evans , Satya N. Majumdar , Kirone Mallick