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Related papers: A predictive coding account of OCD

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This paper gives an explanatory framework for obsessive-compulsive disorder (OCD) based on a generative model of cognition. The framework is constructed using the new concept of a 'formal narrative' which is a sequence of cognitive states…

Neurons and Cognition · Quantitative Biology 2015-03-04 P. J. Moore

Predictive coding is a unifying framework for understanding perception, action and neocortical organization. In predictive coding, different areas of the neocortex implement a hierarchical generative model of the world that is learned from…

Neurons and Cognition · Quantitative Biology 2023-05-22 Linxing Preston Jiang , Rajesh P. N. Rao

The diversity of cognitive deficits and neuropathological processes associated with dementias has encouraged divergence in pathophysiological explanations of disease. Here, we review an alternative framework that emphasises convergent…

Neurons and Cognition · Quantitative Biology 2020-06-12 Ece Kocagoncu , Anastasia Klimovich-Gray , Laura E Hughes , James B Rowe

Obsessive-compulsive disorder (OCD) is a common psychiatric disorder with a lifetime prevalence of 2-3 percent. Recently, brain activity in the resting state is gathering attention as a new means of exploring altered functional connectivity…

The subcortical sensory pathways are the fundamental channels for mapping the outside world to our minds. Sensory pathways efficiently transmit information by adapting neural responses to the local statistics of the sensory input. The…

Neurons and Cognition · Quantitative Biology 2020-03-26 Alejandro Tabas , Glad Mihai , Stefan Kiebel , Robert Trampel , Katharina von Kriegstein

Predictive coding has emerged as a prominent model of how the brain learns through predictions, anticipating the importance accorded to predictive learning in recent AI architectures such as transformers. Here we propose a new framework for…

Machine Learning · Computer Science 2025-12-30 Rajesh P. N. Rao , Dimitrios C. Gklezakos , Vishwas Sathish

Motivation: Behavioral observations are an important resource in the study and evaluation of psychological phenomena, but it is costly, time-consuming, and susceptible to bias. Thus, we aim to automate coding of human behavior for use in…

Computer Vision and Pattern Recognition · Computer Science 2022-05-13 Nicole N. Lønfeldt , Flavia D. Frumosu , A. -R. Cecilie Mora-Jensen , Nicklas Leander Lund , Sneha Das , A. Katrine Pagsberg , Line K. H. Clemmensen

The neuronal circuit that controls obsessive and compulsive behaviors involves a complex network of brain regions (some with known involvement in reward processing). Among these are cortical regions, the striatum and the thalamus (which…

Neurons and Cognition · Quantitative Biology 2015-12-17 Anca Radulescu , Rachel Marra

We present a dynamic model in which the weights are conditioned on an input sample x and are learned to match those that would be obtained by finetuning a base model on x and its label y. This mapping between an input sample and network…

Machine Learning · Computer Science 2023-06-12 Shahar Lutati , Lior Wolf

I present the first complete theory of OCD. OCD occurs when excessive CRH is released in the prefrontal cortex, activating cAMP. cAMP is a major inducer of HCN channels, which promote repeated neural firing. The combination of CRH, which is…

Neurons and Cognition · Quantitative Biology 2024-08-28 Ari Rappoport

Predictive coding is an influential model of cortical neural activity. It proposes that perceptual beliefs are furnished by sequentially minimising "prediction errors" - the differences between predicted and observed data. Implicit in this…

Neurons and Cognition · Quantitative Biology 2022-04-07 Alexander Tschantz , Beren Millidge , Anil K Seth , Christopher L Buckley

We propose a new neurally-inspired model that can learn to encode the global relationship context of visual events across time and space and to use the contextual information to modulate the analysis by synthesis process in a predictive…

Machine Learning · Computer Science 2015-04-17 Mingmin Zhao , Chengxu Zhuang , Yizhou Wang , Tai Sing Lee

We consider the optimization of an uncertain objective over continuous and multi-dimensional decision spaces in problems in which we are only provided with observational data. We propose a novel algorithmic framework that is tractable,…

Machine Learning · Statistics 2018-10-30 Dimitris Bertsimas , Christopher McCord

Making sense of incomplete and conflicting narrative knowledge in the presence of abnormalities, unobservable processes, and other real world considerations is a challenge and crucial requirement for cognitive robotics systems. An added…

Artificial Intelligence · Computer Science 2013-06-05 Manfred Eppe , Mehul Bhatt

Predictive coding offers a potentially unifying account of cortical function -- postulating that the core function of the brain is to minimize prediction errors with respect to a generative model of the world. The theory is closely related…

Artificial Intelligence · Computer Science 2022-07-14 Beren Millidge , Anil Seth , Christopher L Buckley

Major depressive disorder persistently stands as a major public health problem. While some progress has been made toward effective treatments, the neural mechanisms that give rise to the disorder remain poorly understood. In this…

Neurons and Cognition · Quantitative Biology 2025-07-23 Matthew Botvinick , Zeb Kurth-Nelson , Timothy Muller , Will Dabney

Associative memories in the brain receive and store patterns of activity registered by the sensory neurons, and are able to retrieve them when necessary. Due to their importance in human intelligence, computational models of associative…

Machine Learning · Computer Science 2021-09-17 Tommaso Salvatori , Yuhang Song , Yujian Hong , Simon Frieder , Lei Sha , Zhenghua Xu , Rafal Bogacz , Thomas Lukasiewicz

Interpretability research often aims to predict how a model will respond to targeted interventions on specific mechanisms. However, it rarely predicts how a model will respond to unseen input data. This paper explores the promises and…

Machine Learning · Computer Science 2025-07-10 Victoria R. Li , Jenny Kaufmann , Martin Wattenberg , David Alvarez-Melis , Naomi Saphra

Latent world models allow agents to reason about complex environments with high-dimensional observations. However, adapting to new environments and effectively leveraging previous knowledge remain significant challenges. We present…

Machine Learning · Computer Science 2022-06-23 Anson Lei , Bernhard Schölkopf , Ingmar Posner

Machine learning algorithms have achieved superhuman performance in specific complex domains. However, learning online from few examples and compositional learning for efficient generalization across domains remain elusive. In humans, such…

Neurons and Cognition · Quantitative Biology 2024-11-11 V. A. Aksyuk
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