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Demographic change of human populations is one of the central questions for delving into the past of human beings. To identify major population expansions related to male lineages, we sequenced 78 East Asian Y chromosomes at 3.9 Mbp of the…

Populations and Evolution · Quantitative Biology 2015-04-27 Shi Yan , Chuan-Chao Wang , Hong-Xiang Zheng , Wei Wang , Zhen-Dong Qin , Lan-Hai Wei , Yi Wang , Xue-Dong Pan , Wen-Qing Fu , Yun-Gang He , Li-Jun Xiong , Wen-Fei Jin , Shi-Lin Li , Yu An , Hui Li , Li Jin

Short tandem repeats (STRs) and single nucleotide polymorphisms (SNPs) are two kinds of commonly used markers in Y chromosome studies of forensic and population genetics. There has been increasing interest in the cost saving strategy by…

Populations and Evolution · Quantitative Biology 2013-10-22 Chuan-Chao Wang , Ling-Xiang Wang , Rukesh Shrestha , Shaoqing Wen , Manfei Zhang , Xinzhu Tong , Li Jin , Hui Li

Recent studies have shown that hybridization between modern and archaic humans was commonplace in the history of our species. After admixture, some individuals with admixed autosomes carried the modern Homo Sapiens uniparental DNAs, while…

Other Quantitative Biology · Quantitative Biology 2020-03-31 Hongyao Chen , Shi Huang

All genes on the human Y-chromosome were studied using fractal dimension and Shannon entropy. Clear outlier clusters were identified. Among these were 6 sequences that have since been withdrawn as CDSs and 1 additional sequence that is not…

Genomics · Quantitative Biology 2014-04-10 Todd Holden , JianMin Ye

Haplotypes, the global patterns of DNA sequence variation, have important implications for identifying complex traits. Recently, blocks of limited haplotype diversity have been discovered in human chromosomes, intensifying the research on…

Genomics · Quantitative Biology 2012-07-19 Nebojsa Jojic , Vladimir Jojic , David Heckerman

We present the spectroscopic observations for 11 confirmed globular clusters of M31 with the OMR spectrograph on 2.16m telescope at Xinglong site of National Astronomical Observatories, Chinese Academy of Sciences. Nine of our sample…

Cosmology and Nongalactic Astrophysics · Physics 2015-05-30 Zhou Fan , Ya-Fang Huang , Jin-Zeng Li , Xu Zhou , Jun Ma , Hong Wu , Tian-Meng Zhang , Yong-Heng Zhao

We present a two-layer hidden Markov model to detect structure of haplotypes for unrelated individuals. This allows modeling two scales of linkage disequilibrium (one within a group of haplotypes and one between groups), thereby taking…

Quantitative Methods · Quantitative Biology 2013-04-09 Yongtao Guan

Large whole-genome sequencing projects have provided access to much of the rare variation in human populations, which is highly informative about population structure and recent demography. Here, we show how the age of rare variants can be…

Populations and Evolution · Quantitative Biology 2014-06-09 Iain Mathieson , Gil McVean

A haplotype block, or simply a block, is a chromosomal segment, DNA base sequence or string that occurs in only a few variants or types in the genomes of a population of interest, and that has an encapsulated or 'private' frequency…

Populations and Evolution · Quantitative Biology 2024-06-21 Oliver Keatinge Clay

A series of studies have revealed the among-population components of genetic variation are higher for the paternal Y chromosome than for the maternal mitochondrial DNA (mtDNA), which indicates sex-biased migrations in human populations.…

Populations and Evolution · Quantitative Biology 2013-10-30 Chuan-Chao Wang , Li Jin , Hui Li

We have observed the CN features at $\sim$3800 ~\AA~ and 4120~ \AA~ as well as the CH band at $\sim$4300~\AA~ for 145 evolved stars in the Galactic globular cluster M71 using the multi-object spectrograph, Hydra, on the WIYN-3.5m telescope.…

Solar and Stellar Astrophysics · Physics 2020-02-03 Jeffrey M. Gerber , Eileen D. Friel , Enrico Vesperini

Han Chinese experienced substantial population migrations and admixture in history, yet little is known about the evolutionary process of Chinese dialects. Here, we used phylogenetic approaches and admixture inference to explicitly…

Populations and Evolution · Quantitative Biology 2018-02-19 Meng-Han Zhang , Wu-Yun Pan , Shi Yan , Li Jin

Current Y chromosome research is limited in the poor resolution of Y chromosome phylogenetic tree. Entirely sequenced Y chromosomes in numerous human individuals have only recently become available by the advent of next-generation…

Populations and Evolution · Quantitative Biology 2013-10-25 Chuan-Chao Wang , Hui Li

Humans have $23$ pairs of homologous chromosomes. The homologous pairs are almost identical pairs of chromosomes. For the most part, differences in homologous chromosome occur at certain documented positions called single nucleotide…

Information Theory · Computer Science 2015-02-09 Govinda M. Kamath , Eren Şaşoğlu , David Tse

Mendez et al. recently report the identification of a Y chromosome lineage from an African American that is an outgroup to all other known Y haplotypes, and report a time to most recent common ancestor, TMRCA, for human Y lineages that is…

Populations and Evolution · Quantitative Biology 2013-04-24 Melissa A. Wilson Sayres

Observations in integrated light (2200-4800 A, 8 to 11 A resolution, S/N > 20) of 4 M31 globular clusters and of the cores of six gE galaxies made with the HST/FOS are presented and analyzed. These data are supplemented by IUE observations…

(Abridged) We performed the spectroscopic observations of 11 confirmed GCs in M31 with the Xinglong 2.16m telescope and we mainly focus on the fits method and the metallicity gradient for the M31 GC sample. We analyzed and discussed more…

Cosmology and Nongalactic Astrophysics · Physics 2015-06-04 Zhou Fan , Ya-Fang Huang , Jin-Zeng Li , Xu Zhou , Jun Ma , Yong-Heng Zhao

In the last few decades, the human allosomes are engrossed in an intensive attention among researchers. The allosomes are now already been sequenced and found there are about 2000 and 78 genes in human X and Y chromosomes respectively. The…

The origin and diversification of Sino-Tibetan populations have been a long-standing hot debate. However, the limited genetic information of Tibetan populations keeps this topic far from clear. In the present study, we genotyped 15 forensic…

We derive ages, metallicities and [alpha/Fe] ratios from the integrated spectra of 23 globular clusters in M31, by employing multivariate fits to two stellar population models. In parallel we analyze spectra of 21 Galactic globular clusters…

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