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In this paper we use the Cramer-Rao lower uncertainty bound to estimate the maximum precision that could be achieved on the joint simultaneous (or 2D) estimation of photometry and astrometry of a point source measured by a linear CCD…

Instrumentation and Methods for Astrophysics · Physics 2015-06-22 Rene A. Mendez , Jorge F. Silva , Rodrigo Orsotica , Rodrigo Lobos

In this paper we explore the maximum precision attainable in the location of a point source imaged by a pixel array detector in the presence of a background, as a function of the detector properties. For this we use a well-known result from…

Instrumentation and Methods for Astrophysics · Physics 2015-06-15 Rene Mendez , Jorge Silva , Rodrigo Lobos

Image registration is the inference of transformations relating noisy and distorted images. It is fundamental in computer vision, experimental physics, and medical imaging. Many algorithms and analyses exist for inferring shift, rotation,…

Data Analysis, Statistics and Probability · Physics 2019-02-21 Colin B. Clement , Matthew Bierbaum , James P. Sethna

Assessing the quality of parameter estimates for models describing the motion of single molecules in cellular environments is an important problem in fluorescence microscopy. We consider the fundamental data model, where molecules emit…

Quantitative Methods · Quantitative Biology 2021-09-15 A. Marie d'Avigneau , S. S. Singh , R. J. Ober

In this paper, we consider signals with a low-rank covariance matrix which reside in a low-dimensional subspace and can be written in terms of a finite (small) number of parameters. Although such signals do not necessarily have a sparse…

Statistics Theory · Mathematics 2023-07-19 Mahdi Shaghaghi , Sergiy A. Vorobyov

This work focuses on assessing the information-theoretic limits of scene parameter estimation in plenoptic imaging systems. A general framework to compute lower bounds on the parameter estimation error from noisy plenoptic observations is…

Image and Video Processing · Electrical Eng. & Systems 2026-02-03 Abhinav V. Sambasivan , Liam J. Coulter , Richard G. Paxman , Jarvis D. Haupt

Pose estimation is essential for many applications within computer vision and robotics. Despite its uses, few works provide rigorous uncertainty quantification for poses under dense or learned models. We derive a closed-form lower bound on…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Arun Muthukkumar

Interferometric imaging is an emerging technique for particle tracking and mass photometry. Mass or position are estimated from weak signals, coherently scattered from nanoparticles or single molecules, and interfered with a co-propagating…

This paper focuses on potential accuracy of remote sensing images registration. We investigate how this accuracy can be estimated without ground truth available and used to improve registration quality of mono- and multi-modal pair of…

Computer Vision and Pattern Recognition · Computer Science 2016-11-03 M. L. Uss , B. Vozel , V. V. Lukin , K. Chehdi

Advanced super-resolution imaging techniques require specific approaches for accurate and consistent estimation of the achievable spatial resolution. Fisher information supplied to Cramer-Rao bound (CRB) has proved to be a powerful and…

This paper presents a Cramer-Rao bound (CRB) for the estimation of parameters confined to an arbitrary set. Unlike existing results that rely on equality or inequality constraints, manifold structures, or the nonsingularity of the Fisher…

Signal Processing · Electrical Eng. & Systems 2026-01-28 Heedong Do , Angel Lozano

Context. The best precision that can be achieved to estimate the location of a stellar-like object is a topic of permanent interest in the astrometric community. Aims. We analyse bounds for the best position estimation of a stellar-like…

Instrumentation and Methods for Astrophysics · Physics 2016-10-26 Alex Echeverria , Jorge F. Silva , Rene A. Mendez , Marcos Orchard

The detection of landmarks or patterns is of interest for extracting features in biological images. Hence, algorithms for finding these keypoints have been extensively investigated in the literature, and their localization and detection…

Information Theory · Computer Science 2017-10-11 Zsuzsanna Püspöki , Arash Amini , Julien Fageot , John Paul Ward , Michael Unser

Deep learning methods for unsupervised registration often rely on objectives that assume a uniform noise level across the spatial domain (e.g. mean-squared error loss), but noise distributions are often heteroscedastic and input-dependent…

Image and Video Processing · Electrical Eng. & Systems 2024-07-19 Xiaoran Zhang , Daniel H. Pak , Shawn S. Ahn , Xiaoxiao Li , Chenyu You , Lawrence H. Staib , Albert J. Sinusas , Alex Wong , James S. Duncan

Correlative imaging workflows are now widely used in bioimaging and aims to image the same sample using at least two different and complementary imaging modalities. Part of the workflow relies on finding the transformation linking a source…

Quantitative Methods · Quantitative Biology 2021-08-30 Guillaume Potier , Frédéric Lavancier , Stephan Kunne , Perrine Paul-Gilloteaux

As a method to extract information from optical system, imaging can be viewed as a parameter estimation problem. The fundamental precision in locating one emitter or estimating the separation between two incoherent emitters is bounded below…

Quantum Physics · Physics 2021-07-29 Ben Wang , Liang Xu , Lijian Zhang

A variety of recent imaging techniques are able to beat the diffraction limit in fluorescence microcopy by activating and localizing subsets of the fluorescent molecules in the specimen, and repeating this process until all of the molecules…

Optics · Physics 2010-08-27 Alexander R. Small

The goal of this paper is to characterize the best achievable performance for the problem of estimating an unknown parameter having a sparse representation. Specifically, we consider the setting in which a sparsely representable…

Statistics Theory · Mathematics 2009-09-29 Zvika Ben-Haim , Yonina C. Eldar

In some estimation problems, not all the parameters can be identified, which results in singularity of the Fisher Information Matrix (FIM). The Cram\'er-Rao Bound (CRB), which is the inverse of the FIM, is then not defined. To regularize…

Information Theory · Computer Science 2018-07-24 Elisabeth de Carvalho , Dirk Slock

Methods for medical image registration infer geometric transformations that align pairs/groups of images by maximising an image similarity metric. This problem is ill-posed as several solutions may have equivalent likelihoods, also…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Aisha L. Shuaibu , Ivor J. A. Simpson
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