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Background. Health economic evaluations of interventions against infectious diseases are commonly based on the predictions of ordinary differential equation (ODE) systems or Markov models (MMs). Standard MMs are static, whereas ODE systems…

Methodology · Statistics 2018-09-05 Katrin Haeussler , Ardo van den Hout , Gianluca Baio

Background: Recently developed techniques to study the spread of infectious diseases through networks make assumptions that the initial proportion infected is infinitesimal and the population behavior is static throughout the epidemic. The…

Populations and Evolution · Quantitative Biology 2012-08-17 Joel C. Miller

To forecast the time dynamics of an epidemic, we propose a discrete stochastic model that unifies and generalizes previous approaches to the subject. Viewing a given population of individuals or groups of individuals with given health state…

In the Staged Progression (SP) epidemic models, infected individuals are classified into a suitable number of states. The goal of these models is to describe as closely as possible the effect of differences in infectiousness exhibited by…

Dynamical Systems · Mathematics 2024-02-08 Luis Sanz-Lorenzo , Rafael Bravo de la Parra

Moment-closure techniques are commonly used to generate low-dimensional deterministic models to approximate the average dynamics of stochastic systems on networks. The quality of such closures is usually difficult to asses and the…

Populations and Evolution · Quantitative Biology 2015-05-14 Lorenzo Pellis , Thomas House , Matt J. Keeling

We introduce non-Markovian SIR epidemic spreading model inspired by the characteristics of the COVID-19, by considering discrete- and continuous-time versions. The incubation period, delayed infectiousness and the distribution of the…

Physics and Society · Physics 2022-06-22 Lasko Basnarkov , Igor Tomovski , Trifce Sandev , Ljupco Kocarev

The main aim of the work is to present a general class of two time scales discrete-time epidemic models. In the proposed framework the disease dynamics is considered to act on a slower time scale than a second different process that could…

Dynamical Systems · Mathematics 2024-02-07 Luis Sanz-Lorenzo , Rafael Bravo de la Parra

Epidemiological forecasting from surveillance data is a hard problem and hybridizing mechanistic compartmental models with neural models is a natural direction. The mechanistic structure helps keep trajectories epidemiologically plausible,…

Machine Learning · Computer Science 2026-02-09 Yiqi Su , Ray Lee , Jiaming Cui , Naren Ramakrishnan

Although viral spreading processes taking place in networks are often analyzed using Markovian models in which both the transmission and the recovery times follow exponential distributions, empirical studies show that, in many real…

Social and Information Networks · Computer Science 2019-03-19 Masaki Ogura , Victor M. Preciado

The time variation of contacts in a networked system may fundamentally alter the properties of spreading processes and affect the condition for large-scale propagation, as encoded in the epidemic threshold. Despite the great interest in the…

Physics and Society · Physics 2015-04-14 Eugenio Valdano , Luca Ferreri , Chiara Poletto , Vittoria Colizza

We consider Markovian susceptible-infectious-removed (SIR) dynamics on time-invariant weighted contact networks where the infection and removal processes are Poisson and where network links may be directed or undirected. We prove that a…

Populations and Evolution · Quantitative Biology 2013-12-19 Kieran J. Sharkey , Istvan Z. Kiss , Robert R. Wilkinson , Peter L. Simon

In this paper we provide the derivation of a super compact pairwise model with only 4 equations in the context of describing susceptible-infected-susceptible (SIS) epidemic dynamics on heterogenous networks. The super compact model is based…

Dynamical Systems · Mathematics 2015-03-04 Péter L. Simon , Istvan Z. Kiss

Connectivity patterns in intermittently-connected mobile networks (ICMN) can be modeled as edge-Markovian dynamic graphs. We propose a new model for epidemic propagation on such graphs and calculate a closed-form expression that links the…

Networking and Internet Architecture · Computer Science 2016-11-17 John Whitbeck , Vania Conan , Marcelo Dias de Amorim

The SIR model is one of the most prototypical compartmental models in epidemiology. Generalizing this ordinary differential equation (ODE) framework into a spatially distributed partial differential equation (PDE) model is a considerable…

Quantitative Methods · Quantitative Biology 2024-07-11 Su Yang , Weiqi Chu , Panayotis Kevrekidis

In a previous paper Sharkey et al. [13] proved the exactness of closures at the level of triples for Markovian SIR (susceptible-infected-removed) dynamics on tree-like networks. This resulted in a deterministic representation of the…

Probability · Mathematics 2013-07-31 Istvan Z. Kiss , Charles G. Morris , Fanni Sélley , Péter L. Simon , Robert R. Wilkinson

Many complex networks exhibit vulnerability to spreading of epidemics, and such vulnerability relates to the viral strain as well as to the network characteristics. For instance, the structure of the network plays an important role in…

Physics and Society · Physics 2015-03-14 Mina Youssef , Caterina Scoglio

Complex networks with pairwise connections have been vastly used for the modeling of interactions within systems. Although these type of models are capable to capture rich structures and different phases within a great variety of…

Statistical Mechanics · Physics 2022-09-14 Gerardo Palafox-Castillo , Arturo Berrones-Santos

In network-based SIS models of infectious disease transmission, infection can only occur between directly connected individuals. This constraint naturally gives rise to spatial correlations between the states of neighboring nodes, as the…

Statistical Mechanics · Physics 2026-03-18 Alexander Leibenzon , Samuel W. S. Johnson , Ruth E. Baker , Michael Assaf

Epidemics in large complete networks is well established. In contrast, we consider epidemics in non-complete networks. We establish the fluid limit macroscopic dynamics of a multi-virus spread over a multipartite network as the number of…

Social and Information Networks · Computer Science 2013-06-27 Augusto Santos , José M. F. Moura , João Xavier

We propose a general Bayesian approach to modeling epidemics such as COVID-19. The approach grew out of specific analyses conducted during the pandemic, in particular an analysis concerning the effects of non-pharmaceutical interventions…

Applications · Statistics 2021-01-01 Samir Bhatt , Neil Ferguson , Seth Flaxman , Axel Gandy , Swapnil Mishra , James A. Scott