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CBCTs in image-guided radiotherapy provide crucial anatomy information for patient setup and plan evaluation. Longitudinal CBCT image registration could quantify the inter-fractional anatomic changes. The purpose of this study is to propose…
Soft robotic instruments could navigate delicate, tortuous anatomy more safely than rigid tools, but clinical adoption is limited by insufficient tip functionalization and real-time feedback at the tissue interface. Few sensing and…
Fourier ptychography (FP) is a recently proposed computational imaging technique for high space-bandwidth product imaging. In real setups such as endoscope and transmission electron microscope, the common sample motion largely degrades the…
During the radiotherapy treatment of patients with lung cancer, the radiation delivered to healthy tissue around the tumor needs to be minimized, which is difficult because of respiratory motion and the latency of linear accelerator…
Surface-guided radiation therapy (SGRT) is now widely used for radiation-dose-free, marker-free patient positioning in modern radiotherapy. We commissioned and clinically implemented a novel SGRT system, LUNA 3D (LAP, Lueneburg, Germany),…
Cone Beam Computed Tomography (CBCT) is widely used in dentistry for diagnostics and treatment planning. CBCT Imaging has a long acquisition time and consequently, the patient is likely to move. This motion causes significant artifacts in…
Quantification of local metabolic tumor volume (MTV) chan-ges after Chemo-radiotherapy would allow accurate tumor response evaluation. Currently, local MTV changes in esophageal (soft-tissue) cancer are measured by registering follow-up PET…
In conventional 2D DCE-US, motion correction algorithms take advantage of accompanying side-by-side anatomical Bmode images that contain time-stable features. However, current commercial models of 3D DCE-US do not provide side-by-side Bmode…
Pancreatic cancer, which has a low survival rate, is one of the most challenging cancers to diagnose and treat effectively. Early detection through abdominal computed tomography (CT) scans is crucial, yet complicated by the pancreas'…
While spike trains are obviously not band-limited, the theory of super-resolution tells us that perfect recovery of unknown spike locations and weights from low-pass Fourier transform measurements is possible provided that the minimum…
Active surveillance (AS) is a suitable management option for newly-diagnosed prostate cancer (PCa), which usually presents low to intermediate clinical risk. Patients enrolled in AS have their tumor closely monitored via longitudinal…
Recently we have developed an algorithm for reconstructing volumetric images and extracting 3D tumor motion information from a single x-ray projection. We have demonstrated its feasibility using a digital respiratory phantom with regular…
The purpose of this study was to use various dosimetrical indices to determine the best IMRT modality technique for treating patients with prostate cancer. Ten patients with prostate cancer were included in this study. Intensity modulated…
Earlier detection of pancreatic cancer is key to enabling wider access to curative treatment and reducing cancer deaths; however, screening is presently not viable. Latent indicators of pathology are evident in an individual's disease and…
Proton computed tomography (pCT) is a novel medical imaging modality for mapping the distribution of proton relative stopping power (RSP) in medical objects of interest. Compared to conventional X-ray computed tomography, where range…
In this paper, a novel and robust algorithm is proposed for adaptive beamforming based on the idea of reconstructing the autocorrelation sequence (ACS) of a random process from a set of measured data. This is obtained from the first column…
Four-dimensional computed tomography (4DCT) has been widely used in cancer radiotherapy for accurate target delineation and motion measurement for tumors in thorax and upper abdomen areas. However, 4DCT simulation is associated with much…
Inspired by the success of deep learning applications on restoration of low-dose and sparse CT images, we propose a novel method to reconstruct high-quality 4D cone-beam CT (4DCBCT) images from sparse datasets. Our approach combines the…
Background: Spectral shaping is a computed tomography (CT) dose optimization technique that adjusts source voltage and filtration to reduce patient radiation exposure without compromising image quality. Traditionally, radiation dose has…
Photon-counting computed tomography (PCCT) marks a significant advancement over conventional energy-integrating detector (EID) CT systems. This review highlights PCCT's superior spatial and contrast resolution, reduced radiation dose, and…