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We consider a class of tempered subordinators, namely a class of subordinators with one-dimensional marginal tempered distributions which belong to a family studied in [3]. The main contribution in this paper is a non-central moderate…

Probability · Mathematics 2020-11-05 Nikolai Leonenko , Claudio Macci , Barbara Pacchiarotti

Large deviations in chaotic dynamics have potentially significant and dramatic consequences. We study large deviations of series of finite lengths $N$ generated by chaotic maps. The distributions generally display an exponential decay with…

Chaotic Dynamics · Physics 2022-10-21 Naftali R. Smith

Biochemical reactions involving three or more reactants, called higher-molecular reactions, play an important role in theoretical systems and synthetic biology. In particular, such reactions underpin a variety of important bio-dynamical…

Molecular Networks · Quantitative Biology 2021-01-05 Tomislav Plesa

Stochasticity can play an important role in the dynamics of biologically relevant populations. These span a broad range of scales: from intra-cellular populations of molecules to population of cells and then to groups of plants, animals and…

Statistical Mechanics · Physics 2017-07-04 Michael Assaf , Baruch Meerson

We establish uniqueness for a class of first-order Hamilton-Jacobi equations with Hamiltonians that arise from the large deviations of the empirical measure and empirical flux pair of weakly interacting Markov jump processes. As a corollary…

Probability · Mathematics 2020-09-24 Richard C. Kraaij

We use large deviation methods to calculate rates of noise-induced transitions between states in multistable genetic networks. We analyze a synthetic biochemical circuit, the toggle switch, and compare the results to those obtained from a…

Molecular Networks · Quantitative Biology 2013-05-29 David Marin Roma , Ruadhan A. O'Flanagan , Andrei E. Ruckenstein , Anirvan M. Sengupta , Ranjan Mukhopadhyay

Motivated by metastability in the zero-range process, we consider i.i.d.\ random variables with values in $\N_0$ and Weibull-like (stretched exponential) law $\mathbb P(X_i =k) = c \exp( - k^\alpha)$, $\alpha \in (0,1)$. We condition on…

Probability · Mathematics 2024-05-28 Sabine Jansen

Modeling biological processes is a highly demanding task because not all processes are fully understood. Mathematical models allow us to test hypotheses about possible mechanisms of biological processes. The mathematical mechanisms…

Numerical Analysis · Mathematics 2023-12-11 Cordula Reisch , Hannah Burmester

Employing large deviation theory, we explore current fluctuations of underdamped Brownian motion for the paradigmatic example of a single particle in a one dimensional periodic potential. Two different approaches to the large deviation…

Statistical Mechanics · Physics 2018-03-12 Lukas P. Fischer , Patrick Pietzonka , Udo Seifert

We study an autocatalytic system consisting of several interacting chemical species. We observe a strong dependence of the concentrations of the chemicals on the size of the system. This dependence is caused by the discrete nature of the…

Biological Physics · Physics 2007-05-23 Yuichi Togashi , Kunihiko Kaneko

In molecular simulations, one of the most difficult points is to track the real dynamics of many-body systems from the first principle. The present study shows that step-size dependences have an unexpected effect on simulation results, even…

chao-dyn · Physics 2008-02-03 Ken Umeno

The paper deals with the asymptotic behavior of the bridge of a Gaussian process conditioned to stay in $n$ fixed points at $n$ fixed past instants. In particular, functional large deviation results are stated for small time. Several…

Probability · Mathematics 2016-04-06 L. Caramellino , B. Pacchiarotti

We prove large deviation principles for $\int_0^t \gamma(X_s)ds$, where $X$ is a $d$-dimensional self-similar Gaussian process and $\gamma(x)$ takes the form of the Dirac delta function $\delta(x)$, $|x|^{-\beta}$ with $\beta\in (0,d)$, or…

Probability · Mathematics 2020-01-22 Xiaoming Song

This paper is devoted to study the asymptotic properties for the solution of decoupled forward backward stochastic differential equations with delayed generator. As an application, we establish a large deviation principe for solution of the…

Probability · Mathematics 2022-02-16 Clément Manga , Auguste Aman , Navegué Tuo

Dose-response prediction in cancer is an active application field in machine learning. Using large libraries of \textit{in-vitro} drug sensitivity screens, the goal is to develop accurate predictive models that can be used to guide…

Quantitative Methods · Quantitative Biology 2024-07-02 Leiv Rønneberg , Vidhi Lalchand , Paul D. W. Kirk

Quantum coherence inherently affects the dynamics and the performances of a quantum machine. Coherent control can, at least in principle, enhance the work extraction and boost the velocity of evolution in an open quantum system. Using…

Quantum Physics · Physics 2018-12-10 Vasco Cavina , Andrea Mari , Alberto Carlini , Vittorio Giovannetti

The goal of this paper is to go further in the analysis of the behavior of the number of descents in a random permutation. Via two different approaches relying on a suitable martingale decomposition or on the Irwin-Hall distribution, we…

Probability · Mathematics 2024-11-20 Bernard Bercu , Michel Bonnefont , Adrien Richou

Adaptive Molecular Resolution approaches in Molecular Dynamics are becoming relevant tools for the analysis of molecular liquids characterized by the interplay of different physical scales. The essential difference among these methods is in…

Computational Physics · Physics 2016-11-23 Jinglong Zhu , Rupert Klein , Luigi Delle Site

The theory of large deviations is already the natural language for the statistical physics of equilibrium and non-equilibrium. In the field of disordered systems, the analysis via large deviations is even more useful to describe within a…

Disordered Systems and Neural Networks · Physics 2021-05-12 Cecile Monthus

We obtain sample-path large deviations for a class of one-dimensional stochastic differential equations with bounded drifts and heavy-tailed L\'evy processes. These heavy-tailed L\'evy processes do not satisfy the exponential integrability…

Probability · Mathematics 2023-09-15 Wei Wei , Qiao Huang , Jinqiao Duan