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Related papers: Dependence of DNA persistence length on ionic stre…

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Even though the persistence length $L_P$ of double-stranded DNA plays a pivotal role in cell biology and nanotechnologies, its dependence on ionic strength $I$ lacks a consensual description. Using a high-throughput single-molecule…

Finding a theoretical formula for the persistence length of polyelectrolytes for the whole experimental range of salt concentration is a long standing challenge. Using the Tethered Particle Motion technique, the double-stranded DNA…

Soft Condensed Matter · Physics 2023-06-27 Manoel Manghi , Audrey Denis , Nicolas Destainville , Emmanuel Trizac , Catherine Tardin

Persistence length of dsDNA is known to decrease with increase in ionic concentration of the solution. In contrast to this, here we show that persistence length of dsDNA increases dramatically as a function of ionic liquid (IL)…

Biological Physics · Physics 2018-08-15 Ashok Garai , Debostuti Ghoshdastidar , Sanjib Senapati , Prabal K. Maiti

The persistence length of a single, intrinsically rigid polyelectrolyte chain, above the Manning condensation threshold is investigated theoretically in presence of added salt. Using a loop expansion method, the partition function is…

Statistical Mechanics · Physics 2009-11-07 Gil Ariel , David Andelman

The effect of magnesium ion Mg2+ on the dielectric relaxation of semidilute DNA aqueous solutions has been studied by means of dielectric spectroscopy in the 100 Hz-100 MHz frequency range. De Gennes-Pfeuty-Dobrynin semidilute solution…

Biological Physics · Physics 2013-11-20 Danijel Grgičin , Sanja Dolanski Babić , Tomislav Ivek , Silvia Tomić , Rudi Podgornik

We derive the single molecule equation of state (force-extension relation) for DNA molecules bearing sliding loops and deflection defects. Analytical results are obtained in the large force limit by employing an analogy with instantons in…

Soft Condensed Matter · Physics 2009-11-11 Igor M. Kulic , H. Mohrbach , V. Lobaskin , R. Thaokar , H. Schiessel

The extension of DNA confined to nanochannels has been studied intensively and in detail. Yet quantitative comparisons between experiments and model calculations are difficult because most theoretical predictions involve undetermined…

The flexibility and stiffness of small DNA play a fundamental role ranging from several biophysical processes to nano-technological applications. Here, we estimate the mechanical properties of short double-stranded DNA (dsDNA) having length…

Soft Condensed Matter · Physics 2021-07-09 Supriyo Naskar , Prabal K. Maiti

Single T4-DNA molecules were confined in rectangular-shaped channels with a depth of 300 nm and a width in the range 150-300 nm casted in a poly(dimethylsiloxane) nanofluidic chip. The extensions of the DNA molecules were measured with…

Biological Physics · Physics 2009-11-13 Ce Zhang , Fang Zhang , Jeroen A. van Kan , Johan R. C. van der Maarel

We report on a detailed characterization of complex dielectric response of Na-DNA aqueous solutions by means of low-frequency dielectric spectroscopy (40 Hz - 110 MHz). Results reveal two broad relaxation modes of strength…

Soft Condensed Matter · Physics 2013-05-29 S. Tomic , S. Dolanski Babic , T. Vuletic , S. Krca , D. Ivankovic , L. Griparic , R. Podgornik

DNA stretching experiments are usually interpreted using the worm-like chain model; the persistence length A appearing in the model is then interpreted as the elastic stiffness of the double helix. In fact the persistence length obtained by…

Soft Condensed Matter · Physics 2009-10-30 Philip Nelson

The effects of ionic ordering in DNA water solutions are studied by conductivity experiments. The conductivity measurements are performed for the solutions of DNA with KCl salt in the temperature range from 28 to 70 C. Salt concentration…

Biomolecules · Quantitative Biology 2014-01-06 O. O. Liubysh , O. M. Alekseev , S. Yu. Tkachov , S. M. Perepelytsya

Molecular combing is a powerful and simple method for aligning DNA molecules onto a surface. Using this technique combined with fluorescence microscopy, we observed that the length of lambda-DNA molecules was extended to about 1.6 times…

Biomolecules · Quantitative Biology 2009-11-10 Yu-Ying Liu , Peng-Ye Wang , Shuo-Xing Dou , Wei-Chi Wang , Ping Xie , Hua-Wei Yin , Xing-Dong Zhang

We determine the persistence length, $l_p$, for a bacterial group I ribozyme as a function of concentration of monovalent and divalent cations by fitting the distance distribution functions $P(r)$ obtained from small angle X-ray scattering…

Biomolecules · Quantitative Biology 2009-11-11 G. Caliskan , C. Hyeon , U. Perez-Salas , R. M. Briber , S. A. Woodson , D. Thirumalai

Correlation length exponent $\nu$ for long linear DNA molecules was determined by direct measurement of the average end-to-end distance as a function of the contour length $s$ by means of atomic force microscopy (AFM). Linear DNA, up to…

Soft Condensed Matter · Physics 2009-11-11 Francesco Valle , Melanie Favre , Paolo De Los Rios , Angelo Rosa , Giovanni Dietler

Single molecule studies, at constant force, of the separation of double-stranded DNA into two separated single strands may provide information relevant to the dynamics of DNA replication. At constant applied force, theory predicts that the…

The morphology of DNA is strongly influenced by its surrounding environment, including factors such as pH, salt type and valency, and the presence of polymers. Inorganic salts are known to reduce the DNA chain length through mechanisms like…

Soft Condensed Matter · Physics 2026-03-03 Anuj Chhabra , Sandip Mandal , Yugang Zhang , Oleg Gang , Prabal K. Maiti , Sunita Srivastava

Many charged polymers, including nucleic acids, are locally stiff. Their bending rigidity -- quantified by the persistence length --, depends crucially on Coulombic features, such as the ionic strength of the solution which offers a…

Soft Condensed Matter · Physics 2016-12-21 E. Trizac , T. Shen

Dielectric spectroscopy is used to investigate fundamental length scales of 146 bp short-fragment (nucleosomal) dilute Na-DNA solutions. Two relaxation modes are detected: the high- and the low-frequency mode. Dependence of the…

Soft Condensed Matter · Physics 2008-06-02 S. Tomic , S. Dolanski Babic , T. Ivek , T. Vuletic , S. Krca , F. Livolant , R. Podgornik

We study the variation of the dielectric response of ionic aqueous solutions as function of their ionic strength. The effect of salt on the dielectric constant appears through the coupling between ions and dipolar water molecules. On a…

Soft Condensed Matter · Physics 2013-11-19 Amir Levy , David Andelman , Henri Orland
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