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Estimating and testing for differences in molecular phenotypes (e.g. gene expression, chromatin accessibility, transcription factor binding) across conditions is an important part of understanding the molecular basis of gene regulation.…

Understanding how protein mutations affect protein-nucleic acid binding is critical for unraveling disease mechanisms and advancing therapies. Current experimental approaches are laborious, and computational methods remain limited in…

Quantitative Methods · Quantitative Biology 2025-05-30 Xiang Liu , Junjie Wee , Guo-Wei Wei

Memes convey meaning through the interaction of visual and textual signals, often combining humor, irony, and offense in subtle ways. Detecting harmful or sensitive content in memes requires accurate modeling of these multimodal cues.…

Computation and Language · Computer Science 2026-04-29 Qiyuan Jin

Low-shot image classification is a fundamental task in computer vision, and the emergence of large-scale vision-language models such as CLIP has greatly advanced the forefront of research in this field. However, most existing CLIP-based…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Yibo Miao , Yu Lei , Feng Zhou , Zhijie Deng

Vision-Language Pre-training (VLP) models like CLIP have significantly advanced Remote Sensing Image-Text Retrieval (RSITR). However, existing methods predominantly rely on coarse-grained global alignment, which often overlooks the dense,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Yifan Li , Shiying Wang , Jianqiang Huang

In semantic segmentation, the creation of pixel-level labels for training data incurs significant costs. To address this problem, semi-supervised learning, which utilizes a small number of labeled images alongside unlabeled images to…

Computer Vision and Pattern Recognition · Computer Science 2026-04-09 Takahiro Mano , Reiji Saito , Kazuhiro Hotta

In processing and manufacturing industries, there has been a large push to produce higher quality products and ensure maximum efficiency of processes. This requires approaches to effectively detect and resolve disturbances to ensure optimal…

Machine Learning · Statistics 2021-02-05 Weike Sun , Antonio R. C. Paiva , Peng Xu , Anantha Sundaram , Richard D. Braatz

We introduce a novel, probabilistic binary latent variable model to detect noisy or approximate repeats of patterns in sparse binary data. The model is based on the "Noisy-OR model" (Heckerman, 1990), used previously for disease and topic…

Machine Learning · Statistics 2022-01-27 Christopher Warner , Kiersten Ruda , Friedrich T. Sommer

Micro-Action Recognition (MAR) has gained increasing attention due to its crucial role as a form of non-verbal communication in social interactions, with promising potential for applications in human communication and emotion analysis.…

Computer Vision and Pattern Recognition · Computer Science 2025-04-16 Kun Li , Dan Guo , Guoliang Chen , Chunxiao Fan , Jingyuan Xu , Zhiliang Wu , Hehe Fan , Meng Wang

Motivation: Spliced alignment refers to the alignment of messenger RNA (mRNA) or protein sequences to eukaryotic genomes. It plays a critical role in gene annotation and the study of gene functions. Accurate spliced alignment demands…

Genomics · Quantitative Biology 2025-09-23 Siying Yang , Neng Huang , Heng Li

Vision-Language Pre-training (VLP) has advanced the performance for many vision-language tasks. However, most existing pre-trained models only excel in either understanding-based tasks or generation-based tasks. Furthermore, performance…

Computer Vision and Pattern Recognition · Computer Science 2022-02-16 Junnan Li , Dongxu Li , Caiming Xiong , Steven Hoi

Data augmentation improves the generalization power of deep learning models by synthesizing more training samples. Sample-mixing is a popular data augmentation approach that creates additional data by combining existing samples. Recent…

Computer Vision and Pattern Recognition · Computer Science 2024-03-20 Tsz-Him Cheung , Dit-Yan Yeung

Compound-Protein Interaction (CPI) prediction aims to predict the pattern and strength of compound-protein interactions for rational drug discovery. Existing deep learning-based methods utilize only the single modality of protein sequences…

Biomolecules · Quantitative Biology 2024-02-14 Lirong Wu , Yufei Huang , Cheng Tan , Zhangyang Gao , Bozhen Hu , Haitao Lin , Zicheng Liu , Stan Z. Li

Mix-based augmentation has been proven fundamental to the generalization of deep vision models. However, current augmentations only mix samples at the current data batch during training, which ignores the possible knowledge accumulated in…

Computer Vision and Pattern Recognition · Computer Science 2022-03-15 Lingfeng Yang , Xiang Li , Borui Zhao , Renjie Song , Jian Yang

While generating better negative samples for contrastive learning has been widely studied in the areas of CV and NLP, very few work has focused on graph-structured data. Recently, Mixup has been introduced to synthesize hard negative…

Machine Learning · Computer Science 2023-10-17 Yueqi Ma , Minjie Chen , Xiang Li

Data augmentation remains a widely utilized technique in deep learning, particularly in tasks such as image classification, semantic segmentation, and object detection. Among them, Copy-Paste is a simple yet effective method and gain great…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Qiushi Guo

Contrastive Language-Image Pre-training (CLIP) has demonstrated remarkable generalization ability and strong performance across a wide range of vision-language tasks. However, due to the lack of region-level supervision, CLIP exhibits…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Haoxi Zeng , Haoxuan Li , Yi Bin , Pengpeng Zeng , Xing Xu , Yang Yang , Heng Tao Shen

Partial-label learning (PLL) is an important weakly supervised learning problem, which allows each training example to have a candidate label set instead of a single ground-truth label. Identification-based methods have been widely explored…

Machine Learning · Computer Science 2024-03-28 Shiyu Tian , Hongxin Wei , Yiqun Wang , Lei Feng

Exemplar-based face sketch synthesis methods usually meet the challenging problem that input photos are captured in different lighting conditions from training photos. The critical step causing the failure is the search of similar patch…

Computer Vision and Pattern Recognition · Computer Science 2017-08-03 Yibing Song , Jiawei Zhang , Linchao Bao , Qingxiong Yang

Contrastive Language-Image Pretraining (CLIP) stands out as a prominent method for image representation learning. Various architectures, from vision transformers (ViTs) to convolutional networks (ResNets) have been trained with CLIP to…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Cristian Rodriguez-Opazo , Ehsan Abbasnejad , Damien Teney , Hamed Damirchi , Edison Marrese-Taylor , Anton van den Hengel
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