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We consider a model of asexually reproducing individuals. The birth and death rates of the individuals are affected by a fitness parameter. The rate of mutations that cause the fitnesses to change is proportional to the population size, N.…

Probability · Mathematics 2013-07-24 Michael Kelly

A packed community of exponentially proliferating microbes will spread in size exponentially. However, due to nutrient depletion, mechanical constraints, or other limitations, exponential proliferation is not indefinite, and the spreading…

Biological Physics · Physics 2026-02-02 Meiyi Yao , Joshua M. Jones , Joseph W. Larkin , Andrew Mugler

The margins within the geographic range of species are often specific in terms of ecological and evolutionary processes, and can strongly influence the species' reaction to climate change. One of the frequently observed features at range…

Populations and Evolution · Quantitative Biology 2020-02-28 R. Juhász , B. Oborny

As a population grows, spreading to new environments may favor specialization. In this paper, we introduce and explore a model for specialization at the front of a colony expanding synchronously into new territory. We show through numerical…

Biological Physics · Physics 2023-09-14 Lauren H. Li , Mehran Kardar

Background: The accumulation of deleterious mutations of a population directly contributes to the fate as to how long the population would exist, a process often described as Muller's ratchet with the absorbing phenomenon. The key to…

Populations and Evolution · Quantitative Biology 2012-09-11 Shuyun Jiao , Ping Ao

We study how correlations in the random fitness assignment may affect the structure of fitness landscapes. We consider three classes of fitness models. The first is a continuous phenotype space in which individuals are characterized by a…

Populations and Evolution · Quantitative Biology 2007-05-23 Janko Gravner , Damien Pitman , Sergey Gavrilets

Asymmetric segregation of key proteins at cell division -- be it a beneficial or deleterious protein -- is ubiquitous in unicellular organisms and often considered as an evolved trait to increase fitness in a stressed environment. Here, we…

Populations and Evolution · Quantitative Biology 2019-02-20 Jie Lin , Jiseon Min , Ariel Amir

We consider a discrete-time stochastic growth model on the $d$-dimensional lattice with non-negative real numbers as possible values per site. The growth model describes various interesting examples such as oriented site/bond percolation,…

Probability · Mathematics 2009-12-07 Nobuo Yoshida

We study the statistical properties of population dynamics evolving in a realistic two-dimensional compressible turbulent velocity field. We show that the interplay between turbulent dynamics and population growth and saturation leads to…

Fluid Dynamics · Physics 2015-05-19 Prasad Perlekar , Roberto Benzi , David R. Nelson , Federico Toschi

Theory predicts rapid genetic drift during invasions, yet many expanding populations maintain high genetic diversity. We find that genetic drift is dramatically suppressed when dispersal rates increase with the population density because…

Populations and Evolution · Quantitative Biology 2019-03-29 Gabriel Birzu , Sakib Matin , Oskar Hallatschek , Kirill S. Korolev

This is an introductory review of deterministic mutation-selection models for asexual populations (i.e., quasispecies theory) and related topics. First, the basic concepts of fitness, mutations, and sequence space are introduced. Different…

Populations and Evolution · Quantitative Biology 2007-07-26 Kavita Jain , Joachim Krug

Non-communicable diseases like diabetes, obesity and certain forms of cancer have been increasing in many countries at alarming levels. A difficulty in the conception of policies to reverse these trends is the identification of the drivers…

Physics and Society · Physics 2016-03-29 Lazaros K. Gallos , Pablo Barttfeld , Shlomo Havlin , Mariano Sigman , Hernan A. Makse

Fitness consequence of dispersal depends on property of the entire landscape, which patches are available and what are the cost of moving. These are information that are not available locally when an organism make the decision to disperse.…

Populations and Evolution · Quantitative Biology 2026-01-08 Wayne Liang , Rufus Johnstone

A phase diagram for a one-dimensional fiber bundle model is constructed with a continuous variation in two parameters guiding the dynamics of the model: strength of disorder and range of stress relaxation. When the range of stress…

Statistical Mechanics · Physics 2022-02-22 Subhadeep Roy

The evolutionary force of recombination is lacking in asexually reproducing populations. As a consequence, the population can suffer an irreversible accumulation of deleterious mutations, a phenomenon known as Muller's ratchet. We formulate…

Probability · Mathematics 2007-09-19 A. Etheridge , P. Pfaffelhuber , A. Wakolbinger

The persistence of populations depends on the minimum habitat area required for survival, known as the critical patch size. While most studies assume purely diffusive movement, additional movement components can significantly alter habitat…

Statistical Mechanics · Physics 2025-07-11 Luiz Menon , Pablo de Castro , Celia Anteneodo

Pervasive natural selection can strongly influence observed patterns of genetic variation, but these effects remain poorly understood when multiple selected variants segregate in nearby regions of the genome. Classical population genetics…

Populations and Evolution · Quantitative Biology 2013-06-06 Benjamin H. Good , Aleksandra M. Walczak , Richard A. Neher , Michael M. Desai

The concept of fitness as a measure for a species's success in natural selection is central to the theory of evolution. We here investigate how reproduction rates which are not constant but vary in response to environmental fluctuations,…

Populations and Evolution · Quantitative Biology 2015-10-21 Anna Melbinger , Massimo Vergassola

We consider the barycentric version of the Bak-Sneppen model, a one-dimensional self-organized critical model that describes generalized Keynesian beauty contests with a local interaction rule. We numerically investigate the power spectral…

Statistical Mechanics · Physics 2026-01-06 Abdul Quadir , Haider Hasan Jafri

In growing populations, the fate of mutations depends on their competitive ability against the ancestor and their ability to colonize new territory. Here we present a theory that integrates both aspects of mutant fitness by coupling the…

Populations and Evolution · Quantitative Biology 2023-01-19 Daniel W. Swartz , Hyunseok Lee , Mehran Kardar , Kirill S. Korolev