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Superresolution theory and techniques seek to recover signals from samples in the presence of blur and noise. Discrete image registration can be an approach to fuse information from different sets of samples of the same signal. Quantization…

Computer Vision and Pattern Recognition · Computer Science 2024-12-16 Serap A. Savari

Confocal microscopy has long been a cornerstone technique for visualizing complex interactions and processes within cellular structures. However, achieving super-resolution imaging of multiple organelles and their interactions…

Optics · Physics 2025-08-19 Qinglin Chen , Luwei Wang , Jia Li , Dan Shao , Xiaoyu Weng , Liwei Liu , Dayong Jin , Junle Qu

Here, we report analysis and summary of research in the field of localization microscopy for optical imaging. We introduce the basic elements of super-resolved localization microscopy methods for PALM and STORM, commonly used both in vivo…

Optics · Physics 2021-02-25 Jack W Shepherd , Mark C Leake

Single-molecule fluorescence techniques are essential for investigating the molecular mechanisms in biological processes. However, achieving sub-millisecond temporal resolution to monitor fast molecular dynamics remains a significant…

Optics · Physics 2023-03-02 Sunny Tiwari , Prithu Roy , Jean-Benoît Claude , Jérôme Wenger

Due to quantum fluctuations, non-orthogonal quantum states cannot be distinguished with complete certainty, making their underlying physical parameters difficult to resolve. Traditionally, it has been believed that the linewidth of a system…

Atomic Physics · Physics 2025-07-01 Hao Wu , Grant D. Mitts , Clayton Z. C. Ho , Joshua A. Rabinowitz , Eric R. Hudson

Diffusion models have proven effective for various applications such as images, audio and graph generation. Other important applications are image super-resolution and the solution of inverse problems. More recently, some works have used…

Computer Vision and Pattern Recognition · Computer Science 2023-01-02 Marcelo dos Santos , Rayson Laroca , Rafael O. Ribeiro , João Neves , Hugo Proença , David Menotti

Advancements in imaging technology have enabled hardware to support 10 to 16 bits per channel, facilitating precise manipulation in applications like image editing and video processing. While deep neural networks promise to recover high…

Image and Video Processing · Electrical Eng. & Systems 2025-01-13 Xuanshuo Fu , Danna Xue , Javier Vazquez-Corral

The mathematical theory of compressed sensing (CS) asserts that one can acquire signals from measurements whose rate is much lower than the total bandwidth. Whereas the CS theory is now well developed, challenges concerning hardware…

Information Theory · Computer Science 2013-07-18 Makhlad Chahid , Jerome Bobin , Hamed Shams Mousavi , Emmanuel Candes , Maxime Dahan , Vincent Studer

Fluorescence lifetime imaging microscopy (FLIM) is a powerful quantitative technique that provides metabolic and molecular contrast, offering strong translational potential for label-free, real-time diagnostics. However, its clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Paloma Casteleiro Costa , Parnian Ghapandar Kashani , Xuhui Liu , Alexander Chen , Ary Portes , Julien Bec , Laura Marcu , Aydogan Ozcan

We report on mapping of the local density of states in L3 photonic crystal resonators (PCR) via deterministically positioned single Ge quantum dots (QDs). Perfect site-control of Ge QDs on pre-patterned silicon-on-insulator substrates was…

To be able to resolve molecular-clusters it is crucial to access vital informations (such as, molecule density and cluster-size) that are key to understand disease progression and the underlying mechanism. Traditional single-molecule…

Quantitative Methods · Quantitative Biology 2021-01-27 Partha Pratim Mondal

Super-resolution ultrasound imaging relies on the sub-wavelength localization of microbubble contrast agents. By tracking individual microbubbles, the velocity and flow within microvessels can be estimated. However, a 2D super-resolution…

Absorption microscopy is a powerful technique, enabling the detection of single non- fluorescent molecules at room temperature. So far, the molecular absorption has been probed optically via the attenuation of a probing laser. The…

Applied Physics · Physics 2018-11-21 Miao-Hsuan Chien , Mario Brameshuber , Gerhard J. Schütz , Silvan Schmid

Over the last decade, single-molecule optical microscopy has become the gold-standard approach to decipher complex molecular processes in cellular environments. [1-3] Single-molecule fluorescence microscopy has several advantages such as…

Biological Physics · Physics 2017-11-15 Edakkattuparambil Sidharth Shibu , Nadezda Varkentina , Laurent Cognet , Brahim Lounis

A miniaturized full-frequency encoded illumination (mini-FEI) chip is presented for high-throughput super-resolution imaging using the spatial frequency shift (SFS) effect. A tunable full SFS scheme is achieved through propagating and…

In traditional optical imaging systems, the spatial resolution is limited by the physics of diffraction, which acts as a low-pass filter. The information on sub-wavelength features is carried by evanescent waves, never reaching the camera,…

Optics · Physics 2018-12-13 Oren Solomon , Yonina C. Eldar , Maor Mutzafi , Mordechai Segev

Our work aims at using quantitative imaging tools to complement the limitation of noise encountered by high resolution fluorescence microscopy methods. Several cycles of fluorophore activation, imaging and deactivation produce a sequence of…

Quantitative Methods · Quantitative Biology 2012-02-03 Juliane Liepe , Federico Felizzi , Agata Pernus , Maria Hanulova

Quantum super-resolution involves resolving two sources below the Rayleigh limit using quantum optics. Such a technique would allow high-precision inter-satellite positioning and tracking on communication and navigation constellations. Due…

Quantum Physics · Physics 2024-01-17 Ronakraj K Gosalia , Robert Malaney , Ryan Aguinaldo , Jonathan Green

Supervised deep learning approaches can artificially increase the resolution of microscopy images by learning a mapping between two image resolutions or modalities. However, such methods often require a large set of hard-to-get…

Image and Video Processing · Electrical Eng. & Systems 2024-11-20 Marzieh Gheisari , Auguste Genovesio

Although some convolutional neural networks (CNNs) based super-resolution (SR) algorithms yield good visual performances on single images recently. Most of them focus on perfect perceptual quality but ignore specific needs of subsequent…

Computer Vision and Pattern Recognition · Computer Science 2020-04-02 Bin Wang , Tao Lu , Yanduo Zhang
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