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Maintenance of epidermal thickness is critical to the barrier function of the skin. Decreased tissue thickness, specifically in the stratum corneum (the outermost layer of the tissue), causes discomfort and inflammation, and is related to…

Tissues and Organs · Quantitative Biology 2022-09-13 Claire Miller , Edmund Crampin , James Osborne

Growing experimental evidence shows that cell monolayers can induce long-lived perturbations to their environment, akin to footprints, which in turn influence the global dynamics of the system. Inspired by these observations, we propose a…

Soft Condensed Matter · Physics 2024-09-10 Samuel Bell , Joseph Ackermann , Ananyo Maitra , Raphael Voituriez

Complex systems having metastable elements often demonstrate nearly log-time relaxations and a kind of aging: repeated stimuli weaken the system's relaxational response. Granular matter is known to exhibit a wealth of such behaviors, for…

Soft Condensed Matter · Physics 2014-06-16 V. Y. Zaitsev , V. E. Gusev , V. Tournat , P. Richard

Understanding why we age is a long-lived open problem in evolutionary biology. Aging is prejudicial to the individual and evolutionary forces should prevent it, but many species show signs of senescence as individuals age. Here, I will…

Populations and Evolution · Quantitative Biology 2012-01-24 André C. R. Martins

This paper suggests that aging is influenced synthetically by pro-aging factors such as ROS and anti-aging factors such as protective responses. The anti-aging effect may be side effects of retrograde responses motivated against adverse…

Molecular Networks · Quantitative Biology 2017-10-31 Yaguang Ren , Chao Zhang

We decompose the anomalous diffusive behavior found in a model of aging into its fundamental constitutive causes. The model process is a sum of increments that are iterates of a chaotic dynamical system, the Pomeau-Manneville map. The…

Statistical Mechanics · Physics 2018-11-08 Philipp G. Meyer , Vidushi Adlakha , Holger Kantz , Kevin E. Bassler

Human aging is a process controlled by both genetics and environment. Many studies have been conducted to identify a subset of genes related to aging from the human genome. Biologists implicitly categorize age-related genes into genes that…

Genomics · Quantitative Biology 2023-11-17 Salman Mohamadi , Donald A. Adjeroh

This paper develops a point-mutation model describing the evolutionary dynamics of a population of adult stem cells. Such a model may prove useful for quantitative studies of tissue aging and the emergence of cancer. We consider two modes…

Tissues and Organs · Quantitative Biology 2009-11-10 Emmanuel Tannenbaum , James L. Sherley , Eugene I. Shakhnovich

Systems brought out of equilibrium through a rapid quench from a disordered initial state into an ordered phase undergo physical aging in the form of phase-ordering kinetics, with characteristic dynamical scaling. In many systems, notably…

Statistical Mechanics · Physics 2025-01-10 Henrik Christiansen , Suman Majumder , Wolfhard Janke , Malte Henkel

We use state-of-the-art molecular dynamics simulations to study hydrodynamic effects on aging during kinetics of phase separation in a fluid mixture. The domain growth law shows a crossover from a diffusive regime to a viscous hydrodynamic…

Statistical Mechanics · Physics 2015-06-12 Shaista Ahmad , Federico Corberi , Subir K. Das , Eugenio Lippiello , Sanjay Puri , Marco Zannetti

Ageing of organic glasses to the equilibrium liquid state is studied by measuring the dielectric loss utilizing a microregulator where temperature is controlled by means of a Peltier element. Compared to conventional equipment the new…

Soft Condensed Matter · Physics 2011-07-18 Niels Boye Olsen , Tina Hecksher , Kristine Niss , Jeppe C. Dyre

The paper discusses a connection between asymmetric reproduction -- that is reproduction in a parent-child relationship where the parent does not mutate during reproduction --, the fact that all non-viral lifeforms bear genes of their…

Populations and Evolution · Quantitative Biology 2015-08-11 Norbert Michael Mayer

We introduce a set of stellar models for massive stars whose evolution has been affected by mass transfer in a binary system, at a range of metallicities. As noted by other authors, the effect of such mass transfer is frequently more than…

Astrophysics · Physics 2008-11-26 L. M. Dray , C. A. Tout

The effect of impurities on epitaxial growth in the submonolayer regime is studied using kinetic Monte Carlo simulations of a two-species solid-on-solid growth model. Both species are mobile, and attractive interactions among adatoms and…

Materials Science · Physics 2007-05-23 Miroslav Kotrla , Joachim Krug , Pavel Smilauer

The far-from-equilibrium dynamics of glassy systems share important phenomenological traits. A transition is generally observed from a time-homogeneous dynamical regime to an aging regime where physical changes occur intermittently and, on…

Soft Condensed Matter · Physics 2015-03-13 S. Boettcher , P. Sibani

Young stars form in associations, meaning that young stellar associations provide an ideal environment to measure the age of a nominally coeval population. Isochrone fitting, which is the typical method for measuring the age of a coeval…

Solar and Stellar Astrophysics · Physics 2024-05-09 Kendall Sullivan , Adam L. Kraus

Colloidal gels gradually evolve as their structures reorganize, a process known as aging. Understanding this behavior is essential for fundamental science and practical applications such as drug delivery and tissue engineering. This study…

Soft Condensed Matter · Physics 2025-12-11 Shunichi Saito , Sooyeon Kim , Yuichi Taniguchi , Miho Yanagisawa

Aging to the equilibrium liquid state of organic glasses is studied. The glasses were prepared by cooling the liquid to temperatures just below the glass transition. Aging following a temperature jump was studied by measuring the dielectric…

Soft Condensed Matter · Physics 2013-01-29 Tina Hecksher , Niels Boye Olsen , Kristine Niss , Jeppe C. Dyre

A model is proposed that considers aging and rejuvenation in a soft glassy material as respectively a decrease and an increase in free energy. The aging term is weighted by inverse of characteristic relaxation time suggesting greater…

Soft Condensed Matter · Physics 2015-02-25 Yogesh M. Joshi

A system of coupled chaotic bistable maps on a lattice with randomly distributed impurities is investigated as a model for studying the phenomenon of phase growth in nonuniform media. The statistical properties of the system are…

Pattern Formation and Solitons · Physics 2009-11-13 C. Echeverria , K. Tucci , M. G. Cosenza