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Escherichia coli has long been used as a model organism due to the extensive experimental characterization of its pathways and molecular components. Take chemotaxis as an example, which allows bacteria to sense and swim in response to…

Cell Behavior · Quantitative Biology 2015-12-09 Gabriele Micali , Robert G. Endres

Escherichia coli is a motile bacterium that moves up a chemoattractant gradient by performing a biased random walk composed of alternating runs and tumbles. Previous models of run and tumble chemotaxis neglect one or more features of the…

Quantitative Methods · Quantitative Biology 2007-06-26 J. T. Locsei

Growing living cultures of Escherichia coli bacteria were investigated using real-time in situ rheology and rheo-imaging measurements. In the early stages of growth (lag phase), and when subjected to a constant stationary shear, the…

Biological Physics · Physics 2016-12-21 R. Portela , P. Patrício , P. L. Almeida , R. G. Sobral , J. M. Franco , C. R. Leal

We study single cell E.coli chemotaxis in a spatio-temporally varying attractant environment. Modeling the attractant concentration in the form of a traveling sine wave, we measure in our simulations, the chemotactic drift velocity of the…

Cell Behavior · Quantitative Biology 2025-06-06 Shobhan Dev Mandal , Sakuntala Chatterjee

Escherichia coli is a motile bacterium that moves up a chemoattractant gradient by performing a biased random walk composed of alternating runs and tumbles. This paper presents calculations of the chemotactic drift velocity vd (the mean…

Quantitative Methods · Quantitative Biology 2008-04-16 J. T. Locsei , T. J. Pedley

Bacteria can chemotactically migrate up attractant gradients by controlling run-and-tumble motility patterns. In addition to this well-known chemotactic behaviour, several soil and marine bacterial species perform chemokinesis: they adjust…

Biological Physics · Physics 2021-03-19 Theresa Jakuszeit , James Lindsey-Jones , François J. Peaudecerf , Ottavio A. Croze

Chemotaxis of the bacterium Escherichia coli is well understood in shallow chemical gradients, but its swimming behavior remains difficult to interpret in steep gradients. By focusing on single-cell trajectories from simulations, we…

Cell Behavior · Quantitative Biology 2018-02-14 Gabriele Micali , Remy Colin , Victor Sourjik , Robert G. Endres

Bacterial chemotaxis has long been viewed as operating near the physical limits of sensing, as originally articulated by Berg and Purcell. Recent information-theoretic analyses challenge this view, suggesting that Escherichia coli uses only…

Cell Behavior · Quantitative Biology 2026-05-06 Robert G. Endres

Many chemotactic bacteria inhabit environments in which chemicals appear as localized pulses and evolve by processes such as diffusion and mixing. We show that, in such environments, physical limits on the accuracy of temporal gradient…

Biological Physics · Physics 2016-01-19 Andrew M. Hein , Douglas R. Brumley , Francesco Carrara , Roman Stocker , Simon A. Levin

Bacteria typically reside in heterogeneous environments with various chemogradients where motile cells can gain an advantage over non-motile cells. Since motility is energetically costly, cells must optimize their swimming speed and…

Populations and Evolution · Quantitative Biology 2020-05-05 Gurdip Uppal , Weiyi Hu , Dervis Can Vural

Colonies of bacteria grown on thin agar plate exhibit fractal patterns as a result of adaptation to their environments. The bacterial colony pattern formation is regulated crucially by chemotaxis, the movement of cells along a chemical…

Biological Physics · Physics 2013-05-24 Waipot Ngamsaad , Kannika Khompurngson

In natural environments, solid surfaces present both opportunities and challenges for bacteria. On one hand, they serve as platforms for biofilm formation, crucial for bacterial colonization and resilience in harsh conditions. On the other…

Biological Physics · Physics 2025-07-01 Antai Tao , Guangzhe Liu , Rongjing Zhang , Junhua Yuan

Chemotaxis is the physical phenomenon that bacteria adjust their motions according to chemical stimulus. A classical model for this phenomenon is a kinetic equation that describes the velocity jump process whose tumbling/transition kernel…

Analysis of PDEs · Mathematics 2024-01-11 Kathrin Hellmuth , Christian Klingenberg , Qin Li , Min Tang

We show how the competition between sensing and adaptation can result in a performance peak in E.coli chemotaxis using extensive numerical simulations in a detailed theoretical model. Receptor clustering amplifies the input signal coming…

Cell Behavior · Quantitative Biology 2021-03-17 Shobhan Dev Mandal , Sakuntala Chatterjee

Bacteria such as Escherichia coli move about in a series of runs and tumbles: while a run state (straight motion) entails all the flagellar motors spinning in counterclockwise mode, a tumble is caused by a shift in the state of one or more…

Quantitative Methods · Quantitative Biology 2020-01-08 C. S. Renadheer , Ushasi Roy , Manoj Gopalakrishnan

Collective motion of chemotactic bacteria as E. Coli relies, at the individual level, on a continuous reorientation by runs and tumbles. It has been established that the length of run is decided by a stiff response to a temporal sensingof…

Analysis of PDEs · Mathematics 2018-08-15 Benoît Perthame , Shugo Yasuda

The classical macroscopic chemotaxis equations have previously been derived from an individual-based description of the tactic response of cells that use a "run-and-tumble" strategy in response to environmental cues. Here we derive…

Cell Behavior · Quantitative Biology 2007-05-23 Radek Erban , Hans G. Othmer

Active navigation in disordered media depends on a biased random walk interacting with environmental constraints. Using E. coli chemotactic navigation in agar gels as a model system, we reveal a fundamental trade-off between diffusive…

Soft Condensed Matter · Physics 2025-12-23 Yang Bai , Caiyun He , Weirong Liu , Songtao Cheng , Pan Chu , Liang Luo , Chenli Liu , Xiongfei Fu

In response to a concentration gradient of nutrient, E. coli bacterium modulates the rotational bias of flagellar motors which control its run-and-tumble motion, to migrate towards regions of high nutrient concentration. Presence of…

Cell Behavior · Quantitative Biology 2018-04-04 Subrata Dev , Sakuntala Chatterjee

Aggregation of chemotactic bacteria under a unimodal distribution of chemical cues was investigated by Monte Carlo (MC) simulation based on a kinetic transport equation, which considers an internal adaptation dynamics as well as a finite…

Analysis of PDEs · Mathematics 2022-09-05 Shugo Yasuda