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Many biological examples of fluid-structure interaction, including the transit of red blood cells through the narrow slits in the spleen and the intracellular trafficking of vesicles into dendritic spines, involve the near-contact of…

Numerical Analysis · Mathematics 2017-12-20 Thomas G. Fai , Chris H. Rycroft

Cell motility is one of the most fundamental phenomena underlying biological processes that maintain living organisms alive. Here we introduce a simple model to describe the motility of cells which include not only time-correlated internal…

Biological Physics · Physics 2022-07-13 T. N. Azevedo , L. G. Rizzi

Understanding the behavior of biomolecules such as proteins requires understanding the critical influence of the surrounding fluid (solvent) environment--water with mobile salt ions such as sodium. Unfortunately, for many studies, fully…

Soft Condensed Matter · Physics 2015-05-27 J. P. Bardhan , D. A. Tejani , N. S. Wieckowski , A. Ramaswamy , M. G. Knepley

How morphogenesis depends on cell properties is an active direction of research. Here, we focus on mechanical models of growing plant tissues, where microscopic (sub)cellular structure is taken into account. In order to establish links…

Analysis of PDEs · Mathematics 2023-11-21 Arezki Boudaoud , Annamaria Kiss , Mariya Ptashnyk

We carry out the homogenization of a fluid-structure interaction problem consisting in the periodic inclusions of a viscous fluid in an elastic body. We get a macrostructure model where the body behaves as a viscoelastic material with a…

Analysis of PDEs · Mathematics 2024-05-20 Juan Casado-Díaz

Computational determination of the equilibrium state of heterogeneous phospholipid mem-branes is a significant challenge. We wish to explore the rich phase diagram of these multi-component systems. However, the diffusion and mixing times in…

Biological Physics · Physics 2020-10-28 Yevhen K. Cherniavskyi , Arman Fathizadeh , Ron Elber , D. Peter Tieleman

The Immersed Boundary (IB) method is a mathematical framework for constructing robust numerical methods to study fluid-structure interaction in problems involving an elastic structure immersed in a viscous fluid. The IB formulation uses an…

Numerical Analysis · Mathematics 2017-08-23 Yuanxun Bao , Aleksandar Donev , Boyce E. Griffith , David M. McQueen , Charles S. Peskin

Stochastic agent-based models can account for millions of cells with spatiotemporal movement that can be a function of different factors. However, these simulations can be computationally expensive. In this work, we develop a novel…

Numerical Analysis · Mathematics 2019-09-11 Michael A. Yereniuk , Sarah D. Olson

We describe in detail a recently proposed lattice-Boltzmann model for simulating flows with multiple phases and components. In particular, the focus is on the modeling of one-component fluid systems which obey non-ideal gas equations of…

comp-gas · Physics 2009-10-22 Xiaowen Shan , Hudong Chen

The deformation of an initially spherical capsule, freely suspended in simple shear flow, can be computed analytically in the limit of small deformations [D. Barthes-Biesel, J. M. Rallison, The Time-Dependent Deformation of a Capsule Freely…

Soft Condensed Matter · Physics 2010-08-10 Timm Krüger , Fathollah Varnik , Dierk Raabe

Droplets form a cornerstone of the spatiotemporal organization of biomolecules in cells. These droplets are controlled using physical processes like chemical reactions and imposed gradients, which are costly to simulate using traditional…

Soft Condensed Matter · Physics 2022-06-23 Ajinkya Kulkarni , Estefania Vidal-Henriquez , David Zwicker

The article describes parallel multiphysics simulations of charged particles in microfluidic flows with the waLBerla framework. To this end, three physical effects are coupled: rigid body dynamics, fluid flow modelled by a lattice Boltzmann…

Computational Engineering, Finance, and Science · Computer Science 2014-10-27 Dominik Bartuschat , Ulrich Rüde

We present a new method for the geometric reconstruction of elastic surfaces simulated by the immersed boundary method with the goal of simulating the motion and interactions of cells in whole blood. Our method uses parameter-free radial…

Numerical Analysis · Mathematics 2022-08-31 Andrew Kassen , Aaron Barrett , Varun Shankar , Aaron L. Fogelson

Examining individual components of cellular systems has been successful in uncovering molecular reactions and interactions. However, the challenge lies in integrating these components into a comprehensive system-scale map. This difficulty…

Other Quantitative Biology · Quantitative Biology 2024-07-03 Nima Dehghani

Recent work on particle-based models of tissues has suggested that any finite rate of cell division and cell death is sufficient to fluidize an epithelial tissue. At the same time, experimental evidence has indicated the existence of glassy…

Soft Condensed Matter · Physics 2019-05-07 Michael Czajkowski , Daniel M. Sussman , M. Cristina Marchetti , M. Lisa Manning

Navigating topological transitions in cellular mechanical systems is a significant challenge for existing simulation methods. While abstract models lack predictive capabilities at the cellular level, explicit network representations…

Graphics · Computer Science 2024-04-30 Logan Numerow , Yue Li , Stelian Coros , Bernhard Thomaszewski

Lattice-Boltzmann (LB) simulations are a common tool to numerically estimate the permeability of porous media. For valuable results, the porous structure has to be well resolved resulting in a large computational effort as well as high…

Fluid Dynamics · Physics 2011-09-16 Ariel Narváez , Jens Harting

We propose a method of simulating efficiently many-body interacting fermion lattice models in trapped ions, including highly nonlinear interactions in arbitrary spatial dimensions and for arbitrarily distant couplings. We map products of…

Quantum Physics · Physics 2015-05-30 J. Casanova , A. Mezzacapo , L. Lamata , E. Solano

Optical networks composed of interconnected waveguides are a versatile platform to simulate bosonic physical phenomena. Significant work in the non-interacting regime has demonstrated the capabilities of this platform to simulate many…

Quantum Physics · Physics 2025-05-06 Xinyuan Zheng , Mahmoud Jalali Mehrabad , Avik Dutt , Nathan Schine , Edo Waks

The Lattice Boltzmann Method (LBM) is a computational technique of Computational Fluid Dynamics (CFD) that has gained popularity due to its high parallelism and ability to handle complex geometries with minimal effort. Although LBM…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-09-26 Luigi Crisci , Biagio Cosenza , Giorgio Amati , Matteo Turisini