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Inference about a scalar parameter of interest typically relies on the asymptotic normality of common likelihood pivots, such as the signed likelihood root, the score and Wald statistics. Nevertheless, the resulting inferential procedures…

Statistics Theory · Mathematics 2022-01-07 Ruggero Bellio , Ioannis Kosmidis , Alessandra Salvan , Nicola Sartori

Consider a model parameterized by a scalar parameter of interest and a nuisance parameter vector. Inference about the parameter of interest may be based on the signed root of the likelihood ratio statistic R. The standard normal…

Methodology · Statistics 2007-08-22 Juan Zhang , John E. Kolassa

We describe here the general mathematical approach to constructing likelihoods for fitting observed spectra in one or more dimensions with multiple sources, including the effects of systematic uncertainties represented as nuisance…

Data Analysis, Statistics and Probability · Physics 2011-03-03 J. S. Conway

We describe some recent approaches to likelihood based inference in the presence of nuisance parameters. Our approach is based on plotting the likelihood function and the $p$-value function, using recently developed third order…

Data Analysis, Statistics and Probability · Physics 2007-05-23 N. Reid , D. A. S. Fraser

The asymptotic distribution of the likelihood-ratio statistic for testing parameters on the boundary is well known to be a chi-squared mixture. The mixture weights have been shown to correspond to the intrinsic volumes of an associated…

Methodology · Statistics 2026-01-08 Clara Bertinelli Salucci

In presence of nuisance parameters, profile likelihood inference is often unreliable and biased, particularly in small sample scenario. Over past decades several adjustments have been proposed to modify profile likelihood function in…

Statistics Theory · Mathematics 2016-03-29 Md. Mazharul Islam , Md Hasinur Rahaman Khan

Tuning parameters are parameters involved in an estimating procedure for the purpose of reducing the risk of some other estimator. Examples include the degree of penalization in penalized regression and likelihood problems, as well as the…

Statistics Theory · Mathematics 2026-03-31 Ingrid Dæhlen , Nils Lid Hjort , Ingrid Hobæk Haff

The large-sample behavior of non-degenerate multivariate $U$-statistics of arbitrary degree is investigated under the assumption that their kernel depends on parameters that can be estimated consistently. Mild regularity conditions are…

Statistics Theory · Mathematics 2025-07-22 Alain Desgagné , Christian Genest , Frédéric Ouimet

We examine the normal approximation of the modified likelihood root, an inferential tool from higher-order asymptotic theory, for the linear exponential and location-scale family. We show that the $r^\star$ statistic can be thought of as a…

Methodology · Statistics 2022-01-13 Yanbo Tang , Nancy Reid

When conducting inference for the average treatment effect on the treated with a Synthetic Control Estimator, the vector of control weights is a nuisance parameter which is often constrained, high-dimensional, and may be only partially…

Econometrics · Economics 2025-07-03 Joseph Fry

Maximum likelihood method is widely used for parameter estimation in high energy physics. To consider various systematic uncertainties, tens of or even hundreds of nuisance parameters (NP) are introduced in a likelihood fit. The constraint…

Data Analysis, Statistics and Probability · Physics 2019-07-11 Li-Gang Xia

In some high-dimensional and semiparametric inference problems involving two populations, the parameter of interest can be characterized by two-sample U-statistics involving some nuisance parameters. In this work we first extend the…

Methodology · Statistics 2024-02-02 Yuchen Chen , Jing Lei

We consider inference about a scalar parameter under a non-parametric model based on a one-step estimator computed as a plug in estimator plus the empirical mean of an estimator of the parameter's influence function. We focus on a class of…

Statistics Theory · Mathematics 2019-06-07 Ezequiel Smucler , Andrea Rotnitzky , James M. Robins

We propose a new methodology for denoising, variance-stabilizing and normalizing signals whose both mean and variance are parameterized by a single unknown varying parameter, such as Poisson or scaled chi-squared. Key to our methodology is…

Methodology · Statistics 2017-01-26 Piotr Fryzlewicz

In this paper we show how nuisance parameter marginalized posteriors can be inferred directly from simulations in a likelihood-free setting, without having to jointly infer the higher-dimensional interesting and nuisance parameter posterior…

Cosmology and Nongalactic Astrophysics · Physics 2019-07-17 Justin Alsing , Benjamin Wandelt

In various statistical settings, the goal is to estimate a function which is restricted by the statistical model only through a conditional moment restriction. Prominent examples include the nonparametric instrumental variable framework for…

Methodology · Statistics 2025-05-28 AmirEmad Ghassami , James M. Robins , Andrea Rotnitzky

In the context of likelihood ratio testing with parameters on the boundary, we revisit two situations for which there are some discrepancies in the literature: the case of two parameters of interest on the boundary, with all other…

Statistics Theory · Mathematics 2025-09-03 Clara Bertinelli Salucci , Anders Kvellestad , Riccardo De Bin

Data analysis in science, e.g., high-energy particle physics, is often subject to an intractable likelihood if the observables and observations span a high-dimensional input space. Typically the problem is solved by reducing the…

Data Analysis, Statistics and Probability · Physics 2021-01-14 Stefan Wunsch , Simon Jörger , Roger Wolf , Günter Quast

Treatment effect estimation under unconfoundedness is a fundamental task in causal inference. In response to the challenge of analyzing high-dimensional datasets collected in substantive fields such as epidemiology, genetics, economics, and…

Statistics Theory · Mathematics 2024-10-01 Lin Liu , Xinbo Wang , Yuhao Wang

The paper is concerned with inference for a parameter of interest in models that share a common interpretation for that parameter but that may differ appreciably in other respects. We study the general structure of models under which the…

Statistics Theory · Mathematics 2024-08-06 Heather Battey , Nancy Reid
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