Related papers: Synthetic circuit designs for Earth terraformation
One of the challenges in Synthetic Biology is to design circuits with increasing levels of complexity. While circuits in Biology are complex and subject to natural tradeoffs, most synthetic circuits are simple in terms of the number of…
A novel method for control of dynamical systems, proposed in the paper, ensures an output signal belonging to the given set at any time. The method is based on a special change of coordinates such that the initial problem with given…
The computational treatment of many-electron systems capable of exchanging {electrons and nuclei} with the environment represents one of the outermost frontiers in simulation methodology. The exchanging process occurs in a large variety of…
Carbonate-silicate weathering feedback is thought to stabilize Earth's climate on geologic timescales. If climate warms, faster mineral dissolution and increased rainfall speed up weathering, increasing CO2 drawdown and opposing the initial…
System identification method (SIM) was used to evaluate the Earth equilibrium climate sensitivity. According to our simulations, the equilibrium climate sensitivity was found to be between 2 deg C and 7 deg C. Analysis of the changes in…
A primary motivation for our research in digital ecosystems is the desire to exploit the self-organising properties of biological ecosystems. Ecosystems are thought to be robust, scalable architectures that can automatically solve complex,…
The generation of synthetic data is an essential tool to study complex systems, allowing for example to test models of these in precisely controlled settings, or to parametrize simulation models when data is missing. This paper focuses on…
For decades, it was unknown how electron bifurcating systems in Nature prevented energy-wasting short-circuiting reactions that have large driving forces, so synthetic electron bifurcating molecular machines could not be designed and built.…
Many physical plants that are controlled by embedded systems have safety requirements that need to be respected at all times - any deviations from expected behavior can result in damage to the system (often to the physical plant), the…
The climate system is a forced, dissipative, nonlinear, complex and heterogeneous system that is out of thermodynamic equilibrium. The system exhibits natural variability on many scales of motion, in time as well as space, and it is subject…
Understanding the concept of habitability is related to an evolutionary knowledge of the particular planet-in-question. Additional indications so-called "systemic aspects" of the planetary system as a whole governs a particular planet's…
Synthetic biologists have made great progress over the past decade in developing methods for modular assembly of genetic sequences and in engineering biological systems with a wide variety of functions in various contexts and organisms.…
A reliable understanding of the Earth system is essential for the life quality of modern society. Natural hazards are the cause of most life and resource losses. The ability to define the conditions for a sustainable development of…
Early design decisions strongly influence environmental, economic and social outcomes, yet sustainability assessment tools rarely reveal trade-offs among these three pillars. This study presents a framework for Conflict Mapping and…
An important goal of medical research is to develop methods to recover the loss of cellular function due to mutations and other defects. Many approaches based on gene therapy aim to repair the defective gene or to insert genes with…
Matching mechanisms play a central role in operations management across diverse fields including education, healthcare, and online platforms. However, experimentally comparing a new matching algorithm against a status quo presents some…
Many systems occurring in real-world applications, such as controlling the motions of robots or modeling the spread of diseases, are switched impulsive systems. To ensure that the system state stays in a safe region (e.g., to avoid…
Short-term survival and an exuberant plunge into building our future are generating a new kind of unintended consequence -- hidden fragility. This is a direct effect of the sophistication and structural complexity of the socio-technical…
We view Digital Ecosystems to be the digital counterparts of biological ecosystems, which are considered to be robust, self-organising and scalable architectures that can automatically solve complex, dynamic problems. So, this work is…
Aging is analyzed as the spontaneous loss of adaptivity and increase in fragility that characterizes dynamic systems. Cybernetics defines the general regulatory mechanisms that a system can use to prevent or repair the damage produced by…