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Background: Modern statistical tools provide the ability to compare the information content of observables and provide a path to explore which experiments would be most useful to give insight into and constrain theoretical models. Purpose:…

Nuclear Theory · Physics 2021-12-22 M. Catacora-Rios , G. B. King , A. E. Lovell , F. M. Nunes

The use of high-dimensional data for targeted therapeutic interventions requires new ways to characterize the heterogeneity observed across subgroups of a specific population. In particular, models for partially exchangeable data are needed…

Methodology · Statistics 2020-08-18 Francesco Denti , Federico Camerlenghi , Michele Guindani , Antonietta Mira

When data contains measurement errors, it is necessary to make assumptions relating the observed, erroneous data to the unobserved true phenomena of interest. These assumptions should be justifiable on substantive grounds, but are often…

Machine Learning · Statistics 2020-12-24 Noam Finkelstein , Roy Adams , Suchi Saria , Ilya Shpitser

We investigate the potential of numerical algorithms to decipher the kinetic parameters involved in multi-step chemical reactions. To this end we study a dimerization kinetics of protein as a model system. We follow the dimerization…

Biological Physics · Physics 2014-12-24 Srijeeta Talukder , Shrabani Sen , Ralf Metzler , Suman K Banik , Pinaki Chaudhury

The choice of model class is fundamental in statistical learning and system identification, no matter whether the class is derived from physical principles or is a generic black-box. We develop a method to evaluate the specified model class…

Machine Learning · Statistics 2017-12-20 Andreas Svensson , Dave Zachariah , Thomas B. Schön

Interpreting data with mathematical models is an important aspect of real-world industrial and applied mathematical modeling. Often we are interested to understand the extent to which a particular set of data informs and constrains model…

Methodology · Statistics 2025-03-06 Matthew J Simpson , Ruth E Baker

To cope with the complexity of large networks, a number of dimensionality reduction techniques for graphs have been developed. However, the extent to which information is lost or preserved when these techniques are employed has not yet been…

Molecular Networks · Quantitative Biology 2015-08-28 Hector Zenil , Narsis A. Kiani , Jesper Tegnér

Experimental data in Particle and Nuclear physics, Particle Astrophysics and Radiation Protection Dosimetry are obtained from experimental facilities comprising a complex array of sensors, electronics and software. Computer simulation is…

Data Analysis, Statistics and Probability · Physics 2025-03-06 Nikolay D. Gagunashvili

A practical notation can convey valuable intuitions and concisely express new ideas. Information theory is of importance to machine learning, but the notation for information-theoretic quantities is sometimes opaque. We propose a practical…

Machine Learning · Computer Science 2021-12-03 Andreas Kirsch , Yarin Gal

Experience in the physical sciences suggests that the only realistic means of understanding complex systems is through the use of mathematical models. Typically, this has come to mean the identification of quantitative models expressed as…

Artificial Intelligence · Computer Science 2011-11-02 George M. Coghill , Ross D. King , Ashwin Srinivasan

This paper explores Bayesian estimation for categorical data, focusing on simple yet effective models that provide a foundation for applying more advanced methods accurately and reliably in real-world applications. We begin by revisiting…

Methodology · Statistics 2025-09-03 Jan Kalina

Information theory and the framework of information dynamics have been used to provide tools to characterise complex systems. In particular, we are interested in quantifying information storage, information modification and information…

Information Theory · Computer Science 2013-03-25 Oliver Obst , Joschka Boedecker , Benedikt Schmidt , Minoru Asada

From a model-building perspective, we propose a paradigm shift for fitting over-parameterized models. Philosophically, the mindset is to fit models to future observations rather than to the observed sample. Technically, given an imputation…

Methodology · Statistics 2024-12-09 Yiran Jiang , Chuanhai Liu

The presence of symmetries imposes a stringent set of constraints on a system. This constrained structure allows intelligent agents interacting with such a system to drastically improve the efficiency of learning and generalization, through…

Information Theory · Computer Science 2024-10-03 Hippolyte Charvin , Nicola Catenacci Volpi , Daniel Polani

Information theory plays a central role in establishing fundamental limits on what any learning or estimation algorithm can -- and cannot -- achieve, regardless of computational power. In this chapter, we provide an introduction to these…

Information Theory · Computer Science 2026-05-11 Abbas El Gamal , Maxim Raginsky

Safely deploying machine learning models to the real world is often a challenging process. Models trained with data obtained from a specific geographic location tend to fail when queried with data obtained elsewhere, agents trained in a…

Machine Learning · Computer Science 2021-11-02 Marco Federici , Ryota Tomioka , Patrick Forré

In causal inference, sensitivity models assess how unmeasured confounders could alter causal analyses, but the sensitivity parameter -- which quantifies the degree of unmeasured confounding -- is often difficult to interpret. For this…

Methodology · Statistics 2025-09-04 Alec McClean , Zach Branson , Edward H. Kennedy

Mathematical models can provide quantitative insight into immunoreceptor signaling, but require parameterization and uncertainty quantification before making reliable predictions. We review currently available methods and software tools to…

Quantitative Methods · Quantitative Biology 2019-06-28 Eshan D. Mitra , William S. Hlavacek

This study explores the role of information entropy in understanding nuclear density distributions, including both stable configurations and non-traditional structures such as neutron halos and $\alpha$-clustering. By quantifying the…

Nuclear Theory · Physics 2024-10-01 Wei-Hu Ma , Yu-Gang Ma

Many experiments are currently looking for evidence of neutrino mass in the form of neutrino oscillations. Oscillation probabilities are non-linear functions of the neutrino mixing matrix elements, so most comparisons of data to theory are…

High Energy Physics - Phenomenology · Physics 2007-05-23 Doris Jeanne Wagner
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