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The cerebral cortex is composed of multiple cortical areas that exert a wide variety of brain functions. Although human brain neurons are genetically and areally mosaic, the three-dimensional structural differences between neurons in…

Learning and memory relies on synapses changing their strengths in response to neural activity. However there is a substantial gap between the timescales of neural electrical dynamics (1-100 ms) and organism behaviour during learning…

Neurons and Cognition · Quantitative Biology 2023-08-08 Cian O'Donnell

Codifying memories is one of the fundamental problems of modern Neuroscience. The functional mechanisms behind this phenomenon remain largely unknown. Experimental evidence suggests that some of the memory functions are performed by…

Neurons and Cognition · Quantitative Biology 2022-05-17 Ivan Y. Tyukin , Alexander N. Gorban , Carlos Calvo , Julia Makarova , Valeri A. Makarov

Cerebellar-like networks, in which input activity patterns are separated by projection to a much higher-dimensional space before classification, are a recurring neurobiological motif, present in the cerebellum, dentate gyrus, insect…

Neurons and Cognition · Quantitative Biology 2026-03-23 William Dorrell , Peter E. Latham

When choosing between options, we must solve an important binding problem. The values of the options must be associated with information about the action needed to select them. We hypothesize that the brain solves this binding problem…

Neurons and Cognition · Quantitative Biology 2023-02-06 W. Jeffrey Johnston , Justin M. Fine , Seng Bum Michael Yoo , R. Becket Ebitz , Benjamin Y. Hayden

The primary visual cortex processes a large amount of visual information, however, due to its large receptive fields, when multiple stimuli fall within one receptive field, there are computational problems. To solve this problem, the visual…

Neurons and Cognition · Quantitative Biology 2019-04-18 Linda Wang

Elucidating the neurophysiological mechanisms underlying neural pattern formation remains an outstanding challenge in Computational Neuroscience. In this paper, we address the issue of understanding the emergence of neural patterns by…

Neurons and Cognition · Quantitative Biology 2024-06-04 Gregory Dumont , Carmen Oana Tarniceriu

For atoms and crystals with an ideal symmetry, the optical selection rules for electronic transitions are well covered in physics textbooks. However, in studies of material systems one often encounters systems with a weakly distorted…

Atomic Physics · Physics 2018-10-16 G. J. J. Lof , C. H. van der Wal , R. W. A. Havenith

It is an attractive hypothesis that the spatial structure of visual cortical architecture can be explained by the coordinated optimization of multiple visual cortical maps representing orientation preference (OP), ocular dominance (OD),…

Neurons and Cognition · Quantitative Biology 2015-06-03 Lars Reichl , Dominik Heide , Siegrid Löwel , Justin C. Crowley , Matthias Kaschube , Fred Wolf

The visual system is hierarchically organized to process visual information in successive stages. Neural representations vary drastically across the first stages of visual processing: at the output of the retina, ganglion cell receptive…

Neurons and Cognition · Quantitative Biology 2019-01-07 Jack Lindsey , Samuel A. Ocko , Surya Ganguli , Stephane Deny

The brain constantly turns large flows of sensory information into selective representations of the environment. It, therefore, needs to learn to process those sensory inputs that are most relevant for behaviour. It is not well understood…

Neurons and Cognition · Quantitative Biology 2023-01-10 Pouya Baniasadi

Neuronal networks constitute a special class of dynamical systems, as they are formed by individual geometrical components, namely the neurons. In the existing literature, relatively little attention has been given to the influence of…

Neurons and Cognition · Quantitative Biology 2015-05-13 Sebastian Ahnert , Luciano da Fontoura Costa

Grid cells in the medial entorhinal cortex (MEC) of the mammalian brain exhibit a strikingly regular hexagonal firing field over space. These cells are learned after birth and are thought to support spatial navigation but also more abstract…

Neurons and Cognition · Quantitative Biology 2024-10-07 Mufeng Tang , Helen Barron , Rafal Bogacz

It has been recently suggested that a totally asymmetric exclusion process with two species on an open chain could exhibit spontaneous symmetry breaking in some range of the parameters defining its dynamics. The symmetry breaking is…

Condensed Matter · Physics 2009-10-28 C. Godreche , J. M. Luck , M. R. Evans , D. Mukamel , S. Sandow , E. R. Speer

In multicellular organisms, epithelial cells form layers separating compartments responsible for different physiological functions. At the early stage of epithelial layer formation, each cell of an aggregate defines an inner and an outer…

Cell Behavior · Quantitative Biology 2010-02-09 A. Veglio , A. Gamba , M. Nicodemi , F. Bussolino , G. Serini

We report an experimental and theoretical investigation of a system whose dynamics is dominated by an intricate interplay between three key concepts of modern physics: topology, nonlinearity, and spontaneous symmetry breaking. The…

How do different brains create unique visual experiences from identical sensory input? While neural representations vary across individuals, the fundamental architecture underlying these differences remains poorly understood. Here, we…

Neurons and Cognition · Quantitative Biology 2026-02-05 Chihye Han , Michael F. Bonner

Primary visual cortex (V1) is the first stage of cortical image processing, and a major effort in systems neuroscience is devoted to understanding how it encodes information about visual stimuli. Within V1, many neurons respond selectively…

Neurons and Cognition · Quantitative Biology 2017-06-21 William F. Kindel , Elijah D. Christensen , Joel Zylberberg

As a person learns a new skill, distinct synapses, brain regions, and circuits are engaged and change over time. In this paper, we develop methods to examine patterns of correlated activity across a large set of brain regions. Our goal is…

Neurons and Cognition · Quantitative Biology 2013-10-31 Danielle S. Bassett , Nicholas F. Wymbs , M. Puck Rombach , Mason A. Porter , Peter J. Mucha , Scott T. Grafton

As a model of temporally evolving networks, we consider a globally coupled logistic map with variable connection weights. The model exhibits self-organization of network structure, reflected by the collective behavior of units. Structural…

Disordered Systems and Neural Networks · Physics 2009-11-07 Junji Ito , Kunihiko Kaneko