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Spatial relations between neurons in the network with time delays play a crucial role in determining dynamics of the system. During the development of the nervous system different types of neurons group together to enable specific functions…

Adaptation and Self-Organizing Systems · Physics 2019-12-18 Michał Łepek , Piotr Fronczak

During development, the mammalian brain differentiates into specialized regions with distinct functional abilities. While many factors contribute to functional specialization, we explore the effect of neuronal density on the development of…

Neurons and Cognition · Quantitative Biology 2010-04-14 Michael I. Ham , Vadas Gintautas , Marko A. Rodriguez , Ryan A. Bennett , Cara L. Santa Maria , Luis M. A. Bettencourt

Recent developments in network neuroscience have highlighted the importance of developing techniques for analyzing and modeling brain networks. A particularly powerful approach for studying complex neural systems is to formulate generative…

Neurons and Cognition · Quantitative Biology 2022-09-09 Viplove Arora , Enrico Amico , Joaquín Goñi , Mario Ventresca

An important idea in neural information processing is the communication-through-coherence hypothesis, according to which communication between two brain regions is effective only if they are phase-locked. Also of importance is neuronal…

Spatial learning across many species is impaired by lesions in the hippocampus, a subcortical brain structure whose cellular composition changes substantially over its 5 to 6 week lifetime from mainly excitatory neurons during development…

Neurons and Cognition · Quantitative Biology 2022-03-28 Sean Knight

In this paper we study the hydrodynamic limit for a stochastic process describing the time evolution of the membrane potentials of a system of neurons with spatial dependency. We do not impose on the neurons mean-field type interactions.…

Probability · Mathematics 2017-07-14 Aline Duarte , Guilherme Ost , Andrés Rodríguez

The organization of the connectivity between mammalian cortical areas has become a major subject of study, because of its important role in scaffolding the macroscopic aspects of animal behavior and intelligence. In this study we present a…

Neurons and Cognition · Quantitative Biology 2007-05-23 Luciano da F Costa , Marcus Kaiser , Claus C Hilgetag

Increasing experimental evidence suggests that axonal action potential conduction velocity is a highly adaptive parameter in the adult central nervous system. Yet, the effects of this newfound plasticity on global brain dynamics is poorly…

Neurons and Cognition · Quantitative Biology 2019-03-26 Vladimir A. Ivanov , Ioannis E. Polykretis , Konstantinos P. Michmizos

A great variety of systems in nature, society and technology -- from the web of sexual contacts to the Internet, from the nervous system to power grids -- can be modeled as graphs of vertices coupled by edges. The network structure,…

Adaptation and Self-Organizing Systems · Physics 2012-10-10 Petter Holme , Jari Saramäki

Theoretical models of neuronal function consider different mechanisms through which networks learn, classify and discern inputs. A central focus of these models is to understand how associations are established amongst neurons, in order to…

Neurons and Cognition · Quantitative Biology 2015-05-19 Harold P. de Vladar , Eörs Szathmáry

Networks of the brain are composed of a very large number of neurons connected through a random graph and interacting after random delays that both depend on the anatomical distance between cells. In order to comprehend the role of these…

Mathematical Physics · Physics 2014-05-16 Cristobal Quininao , Jonathan Touboul

Neuronal circuits arise as axons and dendrites extend, navigate, and connect to target cells. Axonal growth, in particular, integrates deterministic guidance from substrate mechanics and geometry with stochastic fluctuations generated by…

Biological Physics · Physics 2025-10-10 Cristian Staii

Real-world networks in technology, engineering and biology often exhibit dynamics that cannot be adequately reproduced using network models given by smooth dynamical systems and a fixed network topology. Asynchronous networks give a…

Dynamical Systems · Mathematics 2017-02-07 Christian Bick , Michael Field

The premature fusion of cranial bones, craniosynostosis, affects the correct development of the skull producing morphological malformations in newborns. To assess the susceptibility of each craniofacial articulation to close prematurely, we…

Tissues and Organs · Quantitative Biology 2016-12-28 Borja Esteve-Altava , Toni Valles-Catala , Roger Guimera , Marta Sales-Pardo , Diego Rasskin-Gutman

Human brain networks can be characterized at different temporal or spatial scales given by the age of the subject or the spatial resolution of the neuroimaging method. Integration of data across scales can only be successful if the combined…

Axons functionally link the somato-dendritic compartment to synaptic terminals. Structurally and functionally diverse, they accomplish a central role in determining the delays and reliability with which neuronal ensembles communicate. By…

Neurons and Cognition · Quantitative Biology 2019-05-07 Pepe Alcami , Ahmed El Hady

The mechanisms underlying how activity in the visual pathway may give rise through neural plasticity to many of the features observed experimentally in the early stages of visual processing was provided by Linkser in a seminal, three-paper…

Neurons and Cognition · Quantitative Biology 2020-11-30 Catherine E Davey , David B Grayden , Anthony N Burkitt

During neurodevelopment, neuronal axons navigate through the extracellular environment, guided by various cues to establish connections with distant target cells. Among other factors, axon trajectories are influenced by heterogeneities in…

Biological Physics · Physics 2025-09-09 Christoforos Kassianides , Alain Goriely , Hadrien Oliveri

The human connectome represents a network map of the brain's wiring diagram and the pattern into which its connections are organized is thought to play an important role in cognitive function. The generative rules that shape the topology of…

Unraveling the interplay between connectivity and spatio-temporal dynamics in neuronal networks is a key step to advance our understanding of neuronal information processing. Here we investigate how particular features of network…

Neurons and Cognition · Quantitative Biology 2015-07-21 Michael T. Schaub , Yazan N. Billeh , Costas A. Anastassiou , Christof Koch , Mauricio Barahona