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Purpose: To verify dose delivery and quality assurance of volumetric modulated arc therapy (VMAT) for head and neck cancer. Method: The Imaging and Radiation Oncology Core Houston (IROC-H) head and neck phantom with thermo- luminescent…

The purpose of this study is to give an exact formulation of optimization of volumetric-modulated arc therapy (VMAT) with sliding-window delivery, and to investigate the plan quality effects of decreasing the number of sliding-window sweeps…

Medical Physics · Physics 2018-10-23 Lovisa Engberg , Anders Forsgren

Traditional VMAT optimization often ignores dynamic machine limits, treating delivery time as an emergent property rather than a steerable parameter. This work introduces Dynamic Modulated Arc Therapy (DMAT), an intent-driven framework that…

We propose a novel optimization model for volumetric modulated arc therapy (VMAT) planning that directly optimizes deliverable leaf trajectories in the treatment plan optimization problem, and eliminates the need for a separate…

Medical Physics · Physics 2014-03-05 Dávid Papp , Jan Unkelbach

This study evaluates dynamic conformal arc (DCA) therapy as an alternative to volumetric modulated arc therapy (VMAT) for stereotactic body radiation therapy (SBRT) of lung cancer. The rationale for DCA is lower geometric complexity and…

Medical Physics · Physics 2019-05-07 Rasmus Bokrantz , Minna Wedenberg , Peter Sandwall

Purpose: To develop a novel aperture-based algorithm for volumetric modulated arc therapy (VMAT) treatment plan optimization with high quality and high efficiency. Methods: The VMAT optimization problem is formulated as a large-scale convex…

Medical Physics · Physics 2015-05-19 Chunhua Men , H. Edwin Romeijn , Xun Jia , Steve B. Jiang

In recent years, volumetric modulated arc therapy (VMAT) has been becoming a more and more important radiation technique widely used in clinical application for cancer treatment. One of the key problems in VMAT is treatment plan…

Medical Physics · Physics 2016-01-06 Yu Yang , Bin Dong , Zaiwen Wen

Collimator angle is usually rotated when planning volumetric modulated arc therapy (VMAT) due to the leakage of radiation between multi-leaf collimator (MLC) leaves. We studied the effect of the collimator angles on the results of…

Medical Physics · Physics 2015-03-13 Yong Ho Kim , Ha Ryung Park , Won Taek Kim , Dong Won Kim , Yongkan Ki , Juhye Lee , Jinsuk Bae , Dahl Park

Temporally modulated pulsed radiotherapy (TMPRT) delivers conventional fraction doses of radiation using temporally separated pulses of low doses (<30 cGy) yielding fraction-effective dose rates of around 6.7 cGy/min with the goal to…

Medical Physics · Physics 2026-01-13 Christian Velten , Adam Bayliss , Jiayi Huang , Wolfgang A. Tomé

Purpose: We aims to examine the impact of different head tilt angles on the dose distribution in the whole-brain target area and organs at risk. It also aims to determine the head tilt angle to achieve optimal radiation therapy outcomes.…

Medical Physics · Physics 2024-06-03 Cuiyun Yuan , Sisi Xu , Yang Li , Enzhuo Quan , Dongjie Chen , Jun Liang , Chenbin Liu

Background and Purpose: Increasing the number of arcs in volumetric modulated arc therapy (VMAT) allows for better intensity modulation and may improve plan quality. However, this leads to longer delivery times, which may cause patient…

Medical Physics · Physics 2025-10-31 Nathan Torelli , Madalyne Day , Jan Unkelbach

Purpose: To make the planning of volumetric modulated arc therapy (VMAT) faster and to explore the tradeoffs between planning objectives and delivery efficiency. Methods: A convex multicriteria dose optimization problem is solved for an…

Medical Physics · Physics 2015-05-28 David Craft , Dualta McQuaid , Jeremiah Wala , Wei Chen , Ehsan Salari , Thomas Bortfeld

Ultra-high dose rate electron sources require dose rate independent dosimeters and a calibrated dose control system for accurate delivery. In this study, we developed a single-pulse dose monitoring and a real-time dose-based control system…

Purpose: To improve the delivery efficiency of VMAT by extending the recently published VMAT treatment planning algorithm vmerge to automatically generate optimal partial-arc plans. Methods and materials: A high-quality initial plan is…

Medical Physics · Physics 2015-06-05 Jeremiah Wala , Ehsan Salari , Wei Chen , David Craft

This study investigates the sensitivity and specificity of the MapCHECK phantom housed in MapPHAN to errors in conformal arc Stereotactic Ablative Body Radiotherapy (SABR). A specific focus is applied to Organ At Risk (OAR) dosimetry.…

Medical Physics · Physics 2025-08-22 Nathan I. N. Henry , Christopher M. Thompson , Steven Marsh , Jack D. Aylward

A new delivery option for cancer centers equipped with linear accelerators fitted with multi-leaf collimators (MLC) -- i.e. centers which can perform intensity modulated radiation therapy (IMRT) -- is rotational delivery. In rotational…

Medical Physics · Physics 2009-10-27 David Craft , Thomas Bortfeld

A central problem in the field of radiation therapy (RT) is how to optimally deliver dose to a patient in a way that fully accounts for anatomical position changes over time. As current RT is a static process, where beam intensities are…

Medical Physics · Physics 2019-09-04 Rodney D. Wiersma , Xinmin Liu

Aim: To improve treatment plan robustness with respect to small shifts in patient position during the VMAT treatment by ensuring a linear ramp-like dose profile in treatment field overlap regions. Background: Craniospinal irradiation (CSI)…

Medical Physics · Physics 2016-03-30 Andrej Strojnik , Ignasi Mendez , Primoz Peterlin

Radiotherapy (RT) is a critical cancer treatment, with volumetric modulated arc therapy (VMAT) being a commonly used technique that enhances dose conformity by dynamically adjusting multileaf collimator (MLC) positions and monitor units…

Medical Physics · Physics 2025-06-26 Stefanos Achlatis , Efstratios Gavves , Jan-Jakob Sonke

The purpose of this study is to evaluate the clinical usefulness of modulated arc (mARC) treatment techniques. The mARC treatment plans of the non-small cell lung cancer (NSCLC) patients were performed in order to verify the clinical…

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