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Purpose: To derive a clinically-practical margin formula between clinical target volume (CTV) and planning target volume (PTV) for single-fraction stereotactic radiosurgery (SRS).Methods: In previous publications on the margin between the…
Purpose: This study quantifies the variation in dose-volume histogram (DVH) and normal tissue complication probability (NTCP) metrics for head-and-neck (HN) cancer patients when alternative organ-at-risk (OAR) delineations are used for…
Aim: To examine and quantify set-up errors in patient positioning in head-and-neck radiotherapy and to investigate the impact of the choice of reference isocentre -- on the patient neck or patient skull -- on the magnitude of set-up errors.…
Setting a proper margin is crucial for not only delivering the required radiation dose to a target volume, but also reducing the unnecessary radiation to the adjacent organs at risk. This study investigated the independent one-dimensional…
Resection and whole brain radiotherapy (WBRT) are the standards of care for the treatment of patients with brain metastases (BM) but are often associated with cognitive side effects. Stereotactic radiosurgery (SRS) involves a more targeted…
Purpose: Radiotherapy commonly relies on CT, but there is growing interest in using hybrid PET/MR. Therefore, dedicated hardware setups have been proposed for PET/MR systems which enable imaging in radiotherapy treatment position. These…
Medical image segmentation remains challenging in low-data regimes, where scarce annotations often yield poor generalization and ambiguous boundaries with missing fine structures. Recent self-supervised pretraining has improved…
Precise patient positioning and thus precise positioning of the planning target volume (PTV) is a prerequisite for effective treatment in percutaneous radiation therapy. Conventional imaging modalities used to ensure exact positioning for…
Three-dimensional segmentation in magnetic resonance images (MRI), which reflects the true shape of the objects, is challenging since high-resolution isotropic MRIs are rare and typical MRIs are anisotropic, with the out-of-plane dimension…
The generation of Synthetic Computed Tomography (sCT) images has become a pivotal methodology in modern clinical practice, particularly in the context of Radiotherapy (RT) treatment planning. The use of sCT enables the calculation of doses,…
Background: This study aimed to predict lesion-specific outcomes after stereotactic radiotherapy (SRT) in patients with brain metastases from malignant melanoma (MBM), using clinical, dosimetric, and pretherapeutic MRI data. Methods: In…
Stereotactic radiosurgery (SRS), which delivers high doses of irradiation in a single or few shots to small targets, has been a standard of care for brain metastases. While very effective, SRS currently requires manually intensive…
This paper investigates an extremely challenging problem: barely-supervised volumetric medical image segmentation (BSS). A BSS training dataset consists of two parts: 1) a barely-annotated labeled set, where each labeled image contains only…
Recently, anomaly detection and localization in multimedia data have received significant attention among the machine learning community. In real-world applications such as medical diagnosis and industrial defect detection, anomalies only…
High-quality 3D fetal brain MRI reconstruction from motion-corrupted 2D slices is crucial for clinical diagnosis. Reliable slice-to-volume registration (SVR)-based motion correction and super-resolution reconstruction (SRR) methods are…
Automatic tissue segmentation of fetal brain images is essential for the quantitative analysis of prenatal neurodevelopment. However, producing voxel-level annotations of fetal brain imaging is time-consuming and expensive. To reduce…
Semi-supervised learning relaxes the need of large pixel-wise labeled datasets for image segmentation by leveraging unlabeled data. A prominent way to exploit unlabeled data is to regularize model predictions. Since the predictions of…
Face morphing attacks represent a significant threat to biometric systems as they allow multiple identities to be combined into a single face. While supervised morphing attack detection (MAD) methods have shown promising performance, their…
Spatial precision is often measured using the standard deviation (SD) of the eye position signal or the RMS of the sample-to-sample differences (StoS) signal during fixation. As both measures emerge from statistical theory applied to…
Background: Tumor segmentation in MRI is crucial in radiotherapy (RT) treatment planning for brain tumor patients. Segment anything (SA), a novel promptable foundation model for autosegmentation, has shown high accuracy for multiple…