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We investigate wrinkling patterns in a tri-layer torus consisting of an expanding thin outer layer, an intermediate soft layer and an inner core with a tunable shear modulus, inspired by pattern formation in developmental biologies, such as…

Soft Condensed Matter · Physics 2020-02-25 Xiaoxiao Zhang , Patrick T. Mather , Mark J. Bowick , Teng Zhang

Neurons in the brain are often finely tuned for specific task variables. Moreover, such disentangled representations are highly sought after in machine learning. Here we mathematically prove that simple biological constraints on neurons,…

Neurons and Cognition · Quantitative Biology 2023-04-04 James C. R. Whittington , Will Dorrell , Surya Ganguli , Timothy E. J. Behrens

It is now generally assumed that the heterogeneity of most networks in nature probably arises via preferential attachment of some sort. However, the origin of various other topological features, such as degree-degree correlations and…

Adaptation and Self-Organizing Systems · Physics 2010-03-05 Samuel Johnson , J. Marro , Joaquin J. Torres

Living organisms can demonstrate highly adaptable and sophisticated responses using memory resulting from repeated exposure to external conditions or training. However, realizing similar adaptability in mechanical responses in inanimate,…

Soft Condensed Matter · Physics 2025-12-02 Maitri Mandal , Pappu Acharya , Rituparno Mandal , Sayantan Majumdar

Chirality, or handedness, is a geometrical property denoting a lack of mirror symmetry. Chirality is ubiquitous in nature and is associated with the non-reciprocal interactions observed in complex systems ranging from biomolecules to…

Quantum Physics · Physics 2024-08-08 Jonah S. Peter , Stefan Ostermann , Susanne F. Yelin

The anatomically layered structure of a human brain results in leveled functions. In all these levels of different functions, comparison, feedback and imitation are the universal and crucial mechanisms. Languages, symbols and tools play key…

Neurons and Cognition · Quantitative Biology 2018-02-07 Shengyong Xu , Jingjing Xu , Rujun Dai

A central idea in understanding brains and building artificial intelligence is that structure determines function. Yet, how the brain's complex structure arises from a limited set of genetic instructions remains a key question. The ultra…

Neurons and Cognition · Quantitative Biology 2026-01-28 Xingyu Liu , Yubin Li , Guozhang Chen

The question of controllability of natural and man-made network systems has recently received considerable attention. In the context of the human brain, the study of controllability may not only shed light into the organization and function…

Optimization and Control · Mathematics 2021-02-10 Tommaso Menara , Shi Gu , Danielle S. Bassett , Fabio Pasqualetti

During embryonic morpho-genesis, a collection of individual neurons turns into a functioning network with unique capabilities. Only recently has this most staggering example of emergent process in the natural world, began to be studied.…

Condensed Matter · Physics 2007-05-23 Ronen Segev , Eshel Ben-Jacob

Neurons in the visual cortex are correlated in their variability. The presence of correlation impacts cortical processing because noise cannot be averaged out over many neurons. In an effort to understand the functional purpose of…

Machine Learning · Computer Science 2018-04-04 Shamak Dutta , Bryan Tripp , Graham Taylor

Brain shift, i.e. the change in configuration of the brain after opening the dura mater, is a key problem in neuronavigation. We present an approach to co-register intra-operative microscope images with pre-operative MRI to adapt and…

Computer Vision and Pattern Recognition · Computer Science 2013-03-25 Benjamin Berkels , Ivan Cabrilo , Sven Haller , Martin Rumpf , Carlo Schaller

We investigate the selective forces that promote the emergence of modularity in nature. We demonstrate the spontaneous emergence of modularity in a population of individuals that evolve in a changing environment. We show that the level of…

Populations and Evolution · Quantitative Biology 2009-11-13 Jun Sun , Michael W. Deem

In this paper we first derive solutions which can be interpreted as branes wrapping nontrivial curved manifolds, and then study their cosmological implications. We find that at early times the branes tend to shrink the internal manifold,…

High Energy Physics - Theory · Physics 2009-11-10 Tirthabir Biswas

Self-supervised learning is a powerful way to learn useful representations from natural data. It has also been suggested as one possible means of building visual representation in humans, but the specific objective and algorithm are…

Computer Vision and Pattern Recognition · Computer Science 2021-12-15 Binxu Wang , David Mayo , Arturo Deza , Andrei Barbu , Colin Conwell

Spiral waves are spatial-temporal patterns that can emerge in different systems as heart tissues, chemical oscillators, ecological networks and the brain. These waves have been identified in the neocortex of turtles, rats, and humans,…

Diffusion tractography in brain connectomics often involves tracing axonal trajectories across gray-white matter boundaries in gyral blades of complex cortical convolutions. To date, gyral bias is observed in most tractography algorithms…

Neurons and Cognition · Quantitative Biology 2019-04-15 Ye Wu , Yoonmi Hong , Yuanjing Feng , Dinggang Shen , Pew-Thian Yap

The medial axis transform is a well-known tool for shape recognition. Instead of the object contour, it equivalently describes a binary object in terms of a skeleton containing all centres of maximal inscribed discs. While this shape…

Image and Video Processing · Electrical Eng. & Systems 2025-03-06 Julia Gierke , Pascal Peter

Wrinkling instabilities of thin elastic sheets can be used to generate periodic structures over a wide range of length scales. Viscosity of the thin elastic sheet or its surrounding medium has been shown to be responsible for dynamic…

Soft Condensed Matter · Physics 2024-01-25 Veit Krause , Axel Voigt

The motion of soft-glassy materials (SGM) in a confined geometry is strongly impacted by surface roughness. However, the effect of the spatial distribution of the roughness remains poorly understood from a more quantitative viewpoint. Here…

In this paper, we review widely used statistical analysis frameworks for data defined along cortical and subcortical surfaces that have been developed in last two decades. The cerebral cortex has the topology of a 2D highly convoluted…

Neurons and Cognition · Quantitative Biology 2022-03-15 Moo K. Chung , Jamie L. Hanson , Seth D. Pollak