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The development of Large Language Models (LLMs) has led to significant advancements in natural language processing and enabled numerous applications across various industries. However, many LLM-based solutions operate as open systems…

Cryptography and Security · Computer Science 2025-03-05 Marian Lambert , Thomas Schuster , Nico Döring , Robin Krüger

This paper proposes the Intra Trustcenter Protocol (ITP), a flexible and secure management protocol for communication between arbitrary trustcenter components. Unlike other existing protocols (like PKCS#7, CMP or XKMS) ITP focuses on the…

Cryptography and Security · Computer Science 2009-09-29 V. Karatsiolis , M. Lippert , A. Wiesmaier , A. Pitaev , M. Ruppert , J. Buchmann

The demand of transparency of clinical research results, the need of accelerating the process of transferring innovation in the daily medical practice as well as assuring patient safety and product efficacy make it necessary to extend the…

Software Engineering · Computer Science 2013-01-10 Daniela Luzi , Fabrizio Pecoraro

Data-intensive applications are becoming commonplace in all science disciplines. They are comprised of a rich set of sub-domains such as data engineering, deep learning, and machine learning. These applications are built around efficient…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-08-16 Vibhatha Abeykoon , Supun Kamburugamuve , Chathura Widanage , Niranda Perera , Ahmet Uyar , Thejaka Amila Kanewala , Gregor von Laszewski , Geoffrey Fox

One of the purposes of Big Data systems is to support analysis of data gathered from heterogeneous data sources. Since data warehouses have been used for several decades to achieve the same goal, they could be leveraged also to provide…

Databases · Computer Science 2018-09-13 Darja Solodovnikova , Laila Niedrite

Web services are important in the processing of personal data in the World Wide Web. In light of recent data protection regulations, this processing raises a question about consent or other basis of legal processing. While a consent must be…

Software Engineering · Computer Science 2020-11-06 Kalle Hjerppe , Jukka Ruohonen , Ville Leppänen

Artificial intelligence (AI) has the potential to transform healthcare by supporting more accurate diagnoses and personalized treatments. However, its adoption in practice remains constrained by fragmented data sources, strict privacy…

Software Engineering · Computer Science 2026-02-16 Mira Raheem , Amal Elgammal , Michael Papazoglou , Bernd Krämer , Neamat El-Tazi

We introduce a use case and propose a system for data and knowledge integration in life sciences. In particular, we focus on linking clinical resources (electronic patient records) with scientific documents and data (research articles,…

Computers and Society · Computer Science 2013-04-25 Vit Novacek , Aisha Naseer

Electronic Health Records are electronic data generated during or as a byproduct of routine patient care. Structured, semi-structured and unstructured EHR offer researchers unprecedented phenotypic breadth and depth and have the potential…

Artificial Intelligence · Computer Science 2017-07-26 Vaclav Papez , Spiros Denaxas , Harry Hemingway

Routinely collected data in electronic healthcare records are often underpinned by clinical concept dictionaries. Increasingly data sets from these sources are being made available and used for research purposes, but without additional…

Computers and Society · Computer Science 2020-02-27 Robert C. Free

Practical implementations of high-level languages must provide access to libraries and system services that have APIs specified in a low-level language (usually C). An important characteristic of such mechanisms is the foreign-interface…

Programming Languages · Computer Science 2007-05-23 Kathleen Fisher , Riccardo Pucella , John Reppy

Tackling the information retrieval gap between non-technical database end-users and those with the knowledge of formal query languages has been an interesting area of data management and analytics research. The use of natural language…

Information Retrieval · Computer Science 2020-09-29 Chantal Montgomery , Haruna Isah , Farhana Zulkernine

Managing clinical trial information is currently a significant challenge for the medical industry, as traditional methods are both time-consuming and costly. This paper proposes a simple yet effective methodology to extract and integrate…

Artificial Intelligence · Computer Science 2024-12-20 Berkan Çakır

In this paper, we describe a multidatabase system as 4tiered Client-Server DBMS architectures. We discuss their functional components and provide an overview of their performance characteristics. The first component of this proposed system…

Databases · Computer Science 2009-12-04 Mohammad Ghulam Ali

Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

Computers and Society · Computer Science 2025-11-07 Yusuf Yildiz , Goran Nenadic , Meghna Jani , David A. Jenkins

Parallel data processing has become indispensable for processing applications involving huge data sets. This brings into focus the Graphics Processing Units (GPUs) which emphasize on many-core computing. With the advent of General Purpose…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-05-22 Poorna Banerjee , Amit Dave

High-level synthesis (HLS) tools have brought FPGA development into the mainstream, by allowing programmers to design architectures using familiar languages such as C, C++, and OpenCL. While the move to these languages has brought…

Hardware Architecture · Computer Science 2019-10-11 Johannes de Fine Licht , Torsten Hoefler

Natural language tasks like Named Entity Recognition (NER) in the clinical domain on non-English texts can be very time-consuming and expensive due to the lack of annotated data. Cross-lingual transfer (CLT) is a way to circumvent this…

Computation and Language · Computer Science 2023-06-08 Xavier Fontaine , Félix Gaschi , Parisa Rastin , Yannick Toussaint

Structured data offers a sophisticated mechanism for the organization of information. Existing methodologies for the text-serialization of structured data in the context of large language models fail to adequately address the heterogeneity…

Computation and Language · Computer Science 2024-02-20 YiQiu Guo , Yuchen Yang , Ya Zhang , Yu Wang , Yanfeng Wang

In previous work we described how the process algebra based language PSF can be used in software engineering, using the ToolBus, a coordination architecture also based on process algebra, as implementation model. We also described this…

Software Engineering · Computer Science 2009-08-19 B. Diertens