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This study uses stacked generalization, which is a two-step process of combining machine learning methods, called meta or super learners, for improving the performance of algorithms in step one (by minimizing the error rate of each…

Machine Learning · Computer Science 2020-04-07 Kathleen Kerwin , Nathaniel D. Bastian

Modern applications require methods that are computationally feasible on large datasets but also preserve statistical efficiency. Frequently, these two concerns are seen as contradictory: approximation methods that enable computation are…

Methodology · Statistics 2021-06-11 Darren Homrighausen , Daniel J. McDonald

Unobserved confounding is a fundamental challenge for estimating causal effects. To address unobserved confounding, recent literature has turned to two different approaches -- proxy variables and the use of multiple treatments. The first…

Methodology · Statistics 2026-05-20 Aytijhya Saha , Stephen Bates , Devavrat Shah

Recalibration of binary probabilistic classifiers to a target prior probability is an important task in areas like credit risk management. However, recalibration of a classifier learned on a training dataset to a target on a test dataset in…

Machine Learning · Computer Science 2026-02-02 Dirk Tasche

As the deep neural networks are being applied to complex tasks, the size of the networks and architecture increases and their topology becomes more complicated too. At the same time, training becomes slow and at some instances inefficient.…

Machine Learning · Computer Science 2021-02-22 Massimiliano Esposito , Nader Ganaba

Rerandomization is a modern experimental design technique that repeatedly randomizes treatment assignments until covariates are deemed balanced between treatment groups. This enhances the precision and coherence of causal effect estimators,…

Methodology · Statistics 2025-12-08 Antônio Carlos Herling Ribeiro Junior , Zach Branson

Stacked generalization is a general method of using a high-level model to combine lower-level models to achieve greater predictive accuracy. In this paper we address two crucial issues which have been considered to be a `black art' in…

Artificial Intelligence · Computer Science 2011-05-30 K. M. Ting , I. H. Witten

Linear regression is arguably the most fundamental statistical model; however, the validity of its use in randomized clinical trials, despite being common practice, has never been crystal clear, particularly when stratified or…

Methodology · Statistics 2023-02-14 Wei Ma , Fuyi Tu , Hanzhong Liu

Left censoring can occur with relative frequency when analysing recurrent events in epidemiological studies, especially observational ones. Concretely, the inclusion of individuals that were already at risk before the effective initiation…

Methodology · Statistics 2021-02-24 Gilma Hernández-Herrera , David Moriña , Albert Navarro

For obtaining causal inferences that are objective, and therefore have the best chance of revealing scientific truths, carefully designed and executed randomized experiments are generally considered to be the gold standard. Observational…

Applications · Statistics 2008-11-12 Donald B. Rubin

Non-linear mixed effects modeling and simulation (NLME M&S) is evaluated to be used for standardization with longitudinal data in presence of confounders. Standardization is a well-known method in causal inference to correct for confounding…

Two commonly used methods for improving precision and power in clinical trials are stratified randomization and covariate adjustment. However, many trials do not fully capitalize on the combined precision gains from these two methods, which…

In many practical applications, such as fraud detection, credit risk modeling or medical decision making, classification models for assigning instances to a predefined set of classes are required to be both precise as well as interpretable.…

Machine Learning · Statistics 2021-09-27 Jakob Raymaekers , Wouter Verbeke , Tim Verdonck

Ordinal regression refers to classifying object instances into ordinal categories. Ordinal regression is crucial for applications in various areas like facial age estimation, image aesthetics assessment, and even cancer staging, due to its…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Jinhong Wang , Jintai Chen , Jian Liu , Dongqi Tang , Danny Z. Chen , Jian Wu

Large language models are being widely used across industries to generate content that contributes directly to key performance metrics, such as conversion rates. Pretrained models, however, often fall short when it comes to aligning with…

Machine Learning · Computer Science 2025-06-03 Erfan Loghmani

We provide an approach to exploratory data analysis in matched observational studies with a single intervention and multiple endpoints. In such settings, the researcher would like to explore evidence for actual treatment effects among these…

Methodology · Statistics 2025-12-10 Mengqi Lin , Colin Fogarty

This paper extends the literature on the theoretical properties of synthetic controls to the case of non-linear generative models, showing that the synthetic control estimator is generally biased in such settings. I derive a lower bound for…

Econometrics · Economics 2021-11-23 Oscar Engelbrektson

Over the past ten years, propensity score methods have made an important contribution to improving generalizations from studies that do not select samples randomly from a population of inference. However, these methods require assumptions…

Methodology · Statistics 2021-01-26 Wendy Chan

Synthetic Control methods have recently gained considerable attention in applications with only one treated unit. Their popularity is partly based on the key insight that we can predict good synthetic counterfactuals for our treated unit.…

Econometrics · Economics 2025-07-15 Tzvetan Moev

Accurate and reliable probability predictions are essential for multi-class supervised learning tasks, where well-calibrated models enable rational decision-making. While isotonic regression has proven effective for binary calibration, its…

Machine Learning · Computer Science 2025-12-11 Alon Arad , Saharon Rosset