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Given the cost and duration of phase III and phase IV clinical trials, the development of statistical methods for go/no-go decisions is vital. In this paper, we introduce a Bayesian methodology to compute the probability of success based on…

Methodology · Statistics 2020-10-27 Ethan M. Alt , Matthew A. Psioda , Joseph G. Ibrahim

In computational mechanics, multiple models are often present to describe a physical system. While Bayesian model selection is a helpful tool to compare these models using measurement data, it requires the computationally expensive…

Computation · Statistics 2025-04-14 Subhayan De , Reza Farzad , Patrick T. Brewick , Erik A. Johnson , Steven F. Wojtkiewicz

Bayesian inference provides a powerful tool for leveraging observational data to inform model predictions and uncertainties. However, when such data is limited, Bayesian inference may not adequately constrain uncertainty without the use of…

Methodology · Statistics 2025-06-26 Rebekah D. White , John D. Jakeman , Tim Wildey , Troy Butler

Experimental designs are tools which can drastically reduce the number of simulations required by time-consuming computer codes. One strategy for selecting the values of the inputs, whose response is to be observed, is to choose these…

Statistics Theory · Mathematics 2009-04-17 Astrid Jourdan , Jessica Franco

This paper illustrates novel methods for nonstationary time series modeling along with their applications to selected problems in neuroscience. These methods are semi-parametric in that inferences are derived by combining sequential…

Applications · Statistics 2010-11-03 Fabio Rigat , Jim Q. Smith

Deep nonlinear models pose a challenge for fitting parameters due to lack of knowledge of the hidden layer and the potentially non-affine relation of the initial and observed layers. In the present work we investigate the use of information…

Optimization and Control · Mathematics 2016-12-20 Jacob S. Hunter , Nathan O. Hodas

Chirp signals are frequently used in different areas of science and engineering. MCMC based Bayesian inference is done here for purpose of one step and multiple step prediction in case of one dimensional single chirp signal with i.\ i.\ d.\…

Methodology · Statistics 2014-07-03 Satyaki Mazumder

Current approaches in approximate inference for Bayesian neural networks minimise the Kullback-Leibler divergence to approximate the true posterior over the weights. However, this approximation is without knowledge of the final application,…

Machine Learning · Statistics 2018-05-11 Adam D. Cobb , Stephen J. Roberts , Yarin Gal

Analysis of competing risks data plays an important role in the lifetime data analysis. Recently Feizjavadian and Hashemi (Computational Statistics and Data Analysis, vol. 82, 19-34, 2015) provided a classical inference of a competing risks…

Methodology · Statistics 2021-05-04 Debashis Samanta , Debasis Kundu

Within path sampling framework, we show that probability distribution divergences, such as the Chernoff information, can be estimated via thermodynamic integration. The Boltzmann-Gibbs distribution pertaining to different Hamiltonians is…

Methodology · Statistics 2013-10-18 Silia Vitoratou , Ioannis Ntzoufras

We propose a general algorithm for approximating nonstandard Bayesian posterior distributions. The algorithm minimizes the Kullback-Leibler divergence of an approximating distribution to the intractable posterior distribution. Our method…

Computation · Statistics 2014-07-29 Tim Salimans , David A. Knowles

We consider learning with possibilistic supervision for multi-class classification. For each training instance, the supervision is a normalized possibility distribution that expresses graded plausibility over the classes. From this…

Artificial Intelligence · Computer Science 2026-04-03 Ismaïl Baaj , Pierre Marquis

Predicting human behavior is a difficult and crucial task required for motion planning. It is challenging in large part due to the highly uncertain and multi-modal set of possible outcomes in real-world domains such as autonomous driving.…

Machine Learning · Computer Science 2019-10-15 Yuning Chai , Benjamin Sapp , Mayank Bansal , Dragomir Anguelov

In this paper, we develop a new elegant framework relying on the Kullback-Leibler Information Criterion to address the design of one-stage adaptive detection architectures for multiple hypothesis testing problems. Specifically, at the…

Signal Processing · Electrical Eng. & Systems 2021-03-23 Pia Addabbo , Sudan Han , Fillippo Biondi , Gaetano Giunta , Danilo Orlando

In this article, we propose a novel Bayesian multiple testing formulation for model and variable selection in inverse setups, judiciously embedding the idea of inverse reference distributions proposed by Bhattacharya (2013) in a mixture…

Statistics Theory · Mathematics 2020-07-16 Debashis Chatterjee , Sourabh Bhattacharya

In the era of Big Data, Markov chain Monte Carlo (MCMC) methods, which are currently essential for Bayesian estimation, face significant computational challenges owing to their sequential nature. To achieve a faster and more effective…

Computation · Statistics 2024-11-08 Tomoki Matsumoto

Recent decades have seen an interest in prediction problems for which Bayesian methodology has been used ubiquitously. Sampling from or approximating the posterior predictive distribution in a Bayesian model allows one to make inferential…

Machine Learning · Statistics 2017-09-12 Giri Gopalan

Variational Bayes (VB) is a popular tool for Bayesian inference in statistical modeling. Recently, some VB algorithms are proposed to handle intractable likelihoods with applications such as approximate Bayesian computation. In this paper,…

Numerical Analysis · Mathematics 2021-09-28 Zhijian He , Zhenghang Xu , Xiaoqun Wang

Simultaneous predictive densities for independent Poisson observables are investigated. The observed data and the target variables to be predicted are independently distributed according to different Poisson distributions parametrized by…

Statistics Theory · Mathematics 2021-05-27 Fumiyasu Komaki

Model selection is a cornerstone of statistical inference, where information criteria are widely employed to balance model fit and complexity. However, classical likelihood-based criteria are often highly sensitive to contamination,…

Methodology · Statistics 2026-03-26 Udita Goswami , Shuvashree Mondal
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