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Replication of scientific studies is important for assessing the credibility of their results. However, there is no consensus on how to quantify the extent to which a replication study replicates an original result. We propose a novel…

Methodology · Statistics 2026-05-19 Roberto Macrì-Demartino , Leonardo Egidi , Leonhard Held , Samuel Pawel

There is a growing interest in the analysis of replication studies of original findings across many disciplines. When testing a hypothesis for an effect size, two Bayesian approaches stand out for their principled use of the Bayes factor…

Methodology · Statistics 2024-01-02 Guido Consonni , Leonardo Egidi

We consider the problem of testing positively dependent multiple hypotheses assuming that a prior information about the dependence structure is available. We propose two-step multiple comparisons procedures that exploit the prior…

In many practical applications of multiple hypothesis testing using the False Discovery Rate (FDR), the given hypotheses can be naturally partitioned into groups, and one may not only want to control the number of false discoveries (wrongly…

Methodology · Statistics 2016-11-01 Rina Foygel Barber , Aaditya Ramdas

In large scale multiple testing problems, a two-class empirical Bayes approach can be used to control the false discovery rate (Fdr) for the entire array of hypotheses under study. A sample splitting step is incorporated to modify that…

Computation · Statistics 2019-12-13 Paramita Chakraborty , Chong Ma , John Grego , James Lynch

Many published research results are false, and controversy continues over the roles of replication and publication policy in improving the reliability of research. Addressing these problems is frustrated by the lack of a formal framework…

Other Statistics · Statistics 2015-08-27 Richard McElreath , Paul E. Smaldino

With an increasing number of replication studies performed in psychological science, the question of how to evaluate the outcome of a replication attempt deserves careful consideration. Bayesian approaches allow to incorporate uncertainty…

Applications · Statistics 2018-09-14 Christopher Harms

The reproducibility of scientific findings are an important hallmark of quality and integrity in research. The scientific method requires hypotheses to be subjected to the most crucial tests, and for the results to be consistent across…

Computers and Society · Computer Science 2019-09-11 Dustin Tanksley , Donald C. Wunsch

We consider statistical hypothesis testing simultaneously over a fairly general, possibly uncountably infinite, set of null hypotheses, under the assumption that a suitable single test (and corresponding $p$-value) is known for each…

Methodology · Statistics 2014-02-10 Gilles Blanchard , Sylvain Delattre , Etienne Roquain

In complex clinical trials, multiple research objectives are often grouped into sets of objectives based on their inherent hierarchical relationships. Consequently, the hypotheses formulated to address these objectives are grouped into…

Methodology · Statistics 2016-11-11 Zhiying Qiu , Wenge Guo , Sanat Sarkar

As the volume and complexity of data continue to expand across various scientific disciplines, the need for robust methods to account for the multiplicity of comparisons has grown widespread. A popular measure of type 1 error rate in…

Methodology · Statistics 2024-11-19 Jianliang He , Bowen Gang , Luella Fu

Replication studies are essential for assessing the credibility of claims from original studies. A critical aspect of designing replication studies is determining their sample size; a too small sample size may lead to inconclusive studies…

Methodology · Statistics 2023-08-14 Samuel Pawel , Guido Consonni , Leonhard Held

Multiple hypotheses testing is a core problem in statistical inference and arises in almost every scientific field. Given a sequence of null hypotheses $\mathcal{H}(n) = (H_1,..., H_n)$, Benjamini and Hochberg…

Methodology · Statistics 2015-03-05 Adel Javanmard , Andrea Montanari

We propose sufficient conditions and computationally efficient procedures for false discovery rate control in multiple testing when the $p$-values are related by a known \emph{dependency graph} -- meaning that we assume independence of…

Methodology · Statistics 2025-07-01 Drew T. Nguyen , William Fithian

Meta-analysis combines results from multiple studies aiming to increase power in finding their common effect. It would typically reject the null hypothesis of no effect if any one of the studies shows strong significance. The partial…

Statistics Theory · Mathematics 2016-12-20 Jingshu Wang , Art B. Owen

Conventional multiple hypothesis tests use step-up, step-down, or closed testing methods to control the overall error rates. We will discuss marrying these methods with adaptive multistage sampling rules and stopping rules to perform…

Methodology · Statistics 2011-07-12 Jay Bartroff , Tze Leung Lai

The double hypothesis test (DHT) is a test that allows controlling Type I (producer) and Type II (consumer) errors. It is possible to say whether the batch has a defect rate, p, between 1.5 and 2%, or between 2 and 5%, or between 5 and 10%,…

As a convention, p-value is often computed in frequentist hypothesis testing and compared with the nominal significance level of 0.05 to determine whether or not to reject the null hypothesis. The smaller the p-value, the more significant…

Methodology · Statistics 2020-02-25 Haolun Shi , Guosheng Yin

Merging beliefs requires the plausibility of the sources of the information to be merged. They are typically assumed equally reliable in lack of hints indicating otherwise; yet, a recent line of research spun from the idea of deriving this…

Artificial Intelligence · Computer Science 2021-03-23 Paolo Liberatore

Context: Software Engineering (SE) experiments suffer from threats to validity that may impact their results. Replication allows researchers building on top of previous experiments' weaknesses and increasing the reliability of the findings.…

Software Engineering · Computer Science 2020-04-14 Adrian Santos , Sira Vegas , Fernando Uyaguari , Oscar Dieste , Burak Turhan , Natalia Juristo