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Understanding the implicit bias of training algorithms is of crucial importance in order to explain the success of overparametrised neural networks. In this paper, we study the role of the label noise in the training dynamics of a…

Machine Learning · Statistics 2022-06-22 Loucas Pillaud-Vivien , Julien Reygner , Nicolas Flammarion

Noise, through its interaction with the nonlinearity of the living systems, can give rise to counter-intuitive phenomena such as stochastic resonance, noise-delayed extinction, temporal oscillations, and spatial patterns. In this paper we…

Populations and Evolution · Quantitative Biology 2007-05-23 B. Spagnolo , D. Valenti , A. Fiasconaro

Cells are able to generate phenotypic diversity both during development and in response to stressful and changing environments, aiding survival. The biologically and medically vital process of a cell assuming a functionally important fate…

Cell Behavior · Quantitative Biology 2019-12-16 Ryan Kerr , Sara Jabbari , Iain G. Johnston

In oscillatory reaction-diffusion systems, time-delay feedback can lead to the instability of uniform oscillations with respect to formation of standing waves. Here, we investigate how the presence of additive, Gaussian white noise can…

Statistical Mechanics · Physics 2016-08-17 Michael Stich , Amit K Chattopadhyay

We propose a new method to probe the learning mechanism of Deep Neural Networks (DNN) by perturbing the system using Noise Injection Nodes (NINs). These nodes inject uncorrelated noise via additional optimizable weights to existing…

Machine Learning · Computer Science 2023-05-03 Noam Levi , Itay Bloch , Marat Freytsis , Tomer Volansky

The remarkable robustness of isolated columnar vortices suggests the existence of fundamental constraints that prevent spontaneous disintegration. In this work, we investigate the weakly nonlinear stability of such flows, demonstrating that…

Fluid Dynamics · Physics 2026-02-17 Jinge Wang , Sangjoon Lee , Philip S. Marcus

It is by now established that, remarkably, the addition of noise to a nonlinear system may sometimes facilitate, rather than hamper the detection of weak signals. This phenomenon, usually referred to as stochastic resonance, was originally…

Condensed Matter · Physics 2009-10-31 Redouane Fakir

The effect of external fluctuations on the formation of spatial patterns is analysed by means of a stochastic Swift-Hohenberg model with multiplicative space-correlated noise. Numerical simulations in two dimensions show a shift of the…

Condensed Matter · Physics 2009-10-28 J. Garcia-Ojalvo , J. M. Sancho

We consider signal transaction in a simple neuronal model featuring intrinsic noise. The presence of noise limits the precision of neural responses and impacts the quality of neural signal transduction. We assess the signal transduction…

Biological Physics · Physics 2015-03-17 Michael J. Barber , Manfred L. Ristig

External fluctuations have a wide variety of constructive effects on the dynamical behavior of spatially extended systems, as described by stochastic partial differential equations. A set of paradigmatic situations exhibiting such effects…

Statistical Mechanics · Physics 2007-05-23 J. M. Sancho , J. Garcia-Ojalvo

When cells collide, they often exhibit "contact inhibition of locomotion" (CIL), a behavior in which cells repolarize and migrate away from the site of contact. Experimental CIL outcomes are highly variable - why? Here, we develop a minimal…

Cell Behavior · Quantitative Biology 2026-04-22 Mariia Kryvoruchko , Brian A. Camley

This paper is concerned with stochastic reaction-diffusion kinetics governed by the reaction-diffusion master equation. Specifically, the primary goal of this paper is to provide a mechanistic basis of Turing pattern formation that is…

Quantitative Methods · Quantitative Biology 2015-04-23 Yutaka Hori , Shinji Hara

Based on a non-equilibrium mechanism for spatial pattern formation we study how position information can be controlled by locally coupled discrete dynamical networks, similar to gene regulation networks of cells in a developing…

Molecular Networks · Quantitative Biology 2009-08-26 Thimo Rohlf , Stefan Bornholdt

Learning and decision making in the brain are key processes critical to survival, and yet are processes implemented by non-ideal biological building blocks which can impose significant error. We explore quantitatively how the brain might…

Neurons and Cognition · Quantitative Biology 2011-04-19 Jake Bouvrie , Jean-Jacques Slotine

The interior of a living cell is an active, fluctuating, and crowded environment. Yet, it maintains a high level of coherent organization, which is readily apparent in the intracellular transport network. Membrane-bound compartments called…

Voltage-dependent ion channels determine the electric properties of axonal cell membranes. They not only allow the passage of ions through the cell membrane but also contribute to an additional charging of the cell membrane resulting in the…

Neurons and Cognition · Quantitative Biology 2009-11-13 G. Schmid , I. Goychuk , P. Hanggi

The propagation of noise through parallel regulatory pathways is a characteristic feature of feed-forward loops in genetic networks. Although the contributions of the direct and indirect regulatory pathways of feed-forward loops to output…

Molecular Networks · Quantitative Biology 2025-07-10 Mintu Nandi , Sudip Chattopadhyay , Suman K Banik

Nonlinear dynamical systems subjected to a combination of noise and time-varying forcing can exhibit sudden changes, critical transitions or tipping points where large or rapid dynamic effects arise from changes in a parameter that are…

Chaotic Dynamics · Physics 2024-05-21 Peter Ashwin , Julian Newman , Raphael Römer

A central challenge in computational modeling of dynamic biological systems is parameter inference from experimental time course measurements. However, one would not only like to infer kinetic parameters but also study their variability…

Cells sense their surrounding by employing intracellular signaling pathways that transmit hormonal signals from the cell membrane to the nucleus. TGF-$\beta$/SMAD signaling encodes various cell fates, controls tissue homeostasis and is…

Molecular Networks · Quantitative Biology 2022-10-12 Niklas Kolbe , Lorenz Hexemer , Lukas-Malte Bammert , Alexander Loewer , Mária Lukáčová-Medviďová , Stefan Legewie