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Monte Carlo (MC) simulations play a pivotal role in diverse scientific and engineering domains, with applications ranging from nuclear physics to materials science. Harnessing the computational power of high-performance computing (HPC)…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-03-13 Yehonatan Fridman , Guy Tamir , Uri Steinitz , Gal Oren

Objective: To develop and validate an independent Monet Carlo dose calculation engine to support for software verification of treatment planning systems and quality assurance workflow. Method: GATE Monte Carlo toolkit was employed to…

Medical Physics · Physics 2021-07-27 A. Asadi , A. Akhavanallaf , S. A. Hosseini , N. vosoughi , H. Zaidi

The next great leap toward improving treatment of cancer with radiation will require the combined use of online adaptive and magnetic resonance guided radiation therapy techniques with automatic X-ray beam orientation selection.…

Medical Physics · Physics 2019-08-14 Ryan Neph , Yangsibo Huang , Youming Yang , Ke Sheng

Accurate dose calculation is vitally important for proton therapy. Pencil beam (PB) model-based dose calculation is fast but inaccurate due to the approximation when dealing with inhomogeneities. Monte Carlo (MC) dose calculation is the…

X-ray dose constantly gains interest in the interventional suite. With dose being generally difficult to monitor reliably, fast computational methods are desirable. A major drawback of the gold standard based on Monte Carlo (MC) methods is…

Monte Carlo / Dynamic Code (MC/DC) is a portable Monte Carlo neutron transport package for rapid numerical methods exploration in heterogeneous and HPC contexts, developed under the auspices of the Center for Exascale Monte Carlo Neutron…

Computational Physics · Physics 2025-06-03 Braxton Cuneo , Joanna Piper Morgan , Ilham Variansyah , Kyle E. Niemeyer

OpenMC is an open source Monte Carlo neutral particle transport application that has recently been ported to GPU using the OpenMP target offloading model. We examine the performance of OpenMC at scale on the Frontier, Polaris, and Aurora…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-03-20 John Tramm , Paul Romano , Patrick Shriwise , Amanda Lund , Johannes Doerfert , Patrick Steinbrecher , Andrew Siegel , Gavin Ridley

Accurately and efficiently estimating system performance under uncertainty is paramount in power system planning and operation. Monte Carlo simulation is often used for this purpose, but convergence may be slow, especially when detailed…

Computation · Statistics 2020-10-23 Simon Tindemans , Goran Strbac

During the past years several variance reduction techniques for Monte Carlo electron transport have been developed in order to reduce the electron computation time transport for absorbed dose distribution. We have implemented the Macro…

Medical Physics · Physics 2009-11-13 L. A. Perles , A. de Almeida

Purpose: To investigate the validity of two Monte Carlo simulation absolute dosimetry approaches in the case of a small field dedicated `D'-shaped collimator used for the retinoblastoma treatment with external photon beam radiotherapy.…

Medical Physics · Physics 2018-09-25 P. A. Mayorga , L. Brualla , A. Flühs , W. Sauerwein , A. M. Lallena

The present work is devoted to develop a computational model using the Gate Monte Carlo software for the simulation of a 6MV photon beam given by Elekta Synergy Platform medical linear accelerator treatment head. The model includes the…

Medical Physics · Physics 2013-09-04 Yahya Tayalati , Samir Didi , Mustafa Zerfaoui , Abdellilah Moussaa

We present Generative Monte Carlo (GMC), a novel paradigm for particle transport simulation that integrates generative artificial intelligence directly into the stochastic solution of the linear Boltzmann equation. By reformulating the…

Computational Physics · Physics 2025-12-17 Joseph A. Farmer , Aidan Murray , Johannes Krotz , Ryan G. McClarren

Cancer is a primary cause of morbidity and mortality worldwide. The radiotherapy plays a more and more important role in cancer treatment. In the radiotherapy, the dose distribution maps in patient need to be calculated and evaluated for…

Medical Physics · Physics 2019-10-18 Zhao Peng , Hongming Shan , Tianyu Liu , Xi Pei , Jieping Zhou , Ge Wang , X. George Xu

Purpose: To validate the MC-GPU Monte Carlo code for dosimetric studies in x-ray breast imaging modalities: mammography, digital breast tomosynthesis, contrast enhanced digital mammography and breast-CT. Moreover, to implement and validate…

Medical Physics · Physics 2022-04-06 Rodrigo T. Massera , Rowan M. Thomson , Alessandra Tomal

In recent years, the Hamiltonian Monte Carlo (HMC) algorithm has been found to work more efficiently compared to other popular Markov Chain Monte Carlo (MCMC) methods (such as random walk Metropolis-Hastings) in generating samples from a…

Computation · Statistics 2014-02-18 Andrew L. Beam , Sujit K. Ghosh , Jon Doyle

Purpose: To develop a Monte Carlo (MC) therapeutic dose calculation toolkit of a recently released ring gantry linac in Geant4 (Version 10.7) for secondary dose validation of radiotherapy plan. Methods: For the Halcyon (Varian Medical…

Medical Physics · Physics 2022-10-04 Ruirui Liu , Zhen Ji , Xiandong Zhao , Tianyu Zhao , Abhishek Sethi , Daren Sawkey , Bin Cai

Computed Tomography (CT) imaging, while essential for diagnostics, exposes patients to ionizing radiation. To accurately quantify radiation dosage, this study introduces MIDSX, a specialized open-source Monte Carlo (MC) photon transport…

Medical Physics · Physics 2023-11-29 John Meneghini

Particle-in-Cell (PIC) Monte Carlo (MC) simulations are central to plasma physics but face increasing challenges on heterogeneous HPC systems due to excessive data movement, synchronization overheads, and inefficient utilization of multiple…

The purpose of this work is to develop viable procedures for verifying the applicability of personalized dosimetry in computed tomography (CT) using Monte Carlo-based simulations. Mobile equipment together with customized software was…

Monte Carlo (MC) methods provide the most accurate to-date dose calculations in heterogeneous media and complex geometries, and this spawns increasing interest in incorporating MC calculations into treatment planning quality assurance…

Medical Physics · Physics 2009-01-07 C. Locke , S. Zavgorodni