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Accurate prediction of drug-target interactions (DTI) is crucial for drug discovery. Recently, deep learning (DL) models for show promising performance for DTI prediction. However, these models can be difficult to use for both computer…

Machine Learning · Computer Science 2020-12-11 Kexin Huang , Tianfan Fu , Lucas Glass , Marinka Zitnik , Cao Xiao , Jimeng Sun

Selective classification techniques (also known as reject option) have not yet been considered in the context of deep neural networks (DNNs). These techniques can potentially significantly improve DNNs prediction performance by trading-off…

Machine Learning · Computer Science 2017-06-02 Yonatan Geifman , Ran El-Yaniv

Data poisoning attacks -- where an adversary can modify a small fraction of training data, with the goal of forcing the trained classifier to high loss -- are an important threat for machine learning in many applications. While a body of…

Machine Learning · Computer Science 2020-02-21 Yizhen Wang , Somesh Jha , Kamalika Chaudhuri

Recommender systems have become an integral part of online services to help users locate specific information in a sea of data. However, existing studies show that some recommender systems are vulnerable to poisoning attacks, particularly…

Cryptography and Security · Computer Science 2024-04-24 Thanh Toan Nguyen , Quoc Viet Hung Nguyen , Thanh Tam Nguyen , Thanh Trung Huynh , Thanh Thi Nguyen , Matthias Weidlich , Hongzhi Yin

Microtubule networks (MTs) are a component of a cell that may indicate the presence of various chemical compounds and can be used to recognize properties such as treatment resistance. Therefore, the classification of MT images is of great…

Image and Video Processing · Electrical Eng. & Systems 2020-12-23 Aleksei Shpilman , Dmitry Boikiy , Marina Polyakova , Daniel Kudenko , Anton Burakov , Elena Nadezhdina

With the development of computer-assisted techniques, research communities including biochemistry and deep learning have been devoted into the drug discovery field for over a decade. Various applications of deep learning have drawn great…

Machine Learning · Computer Science 2023-03-07 Wenhao Hu , Yingying Liu , Xuanyu Chen , Wenhao Chai , Hangyue Chen , Hongwei Wang , Gaoang Wang

Skin cancer is one of the most threatening diseases worldwide. However, diagnosing skin cancer correctly is challenging. Recently, deep learning algorithms have emerged to achieve excellent performance on various tasks. Particularly, they…

Image and Video Processing · Electrical Eng. & Systems 2020-12-08 Hongfeng Li , Yini Pan , Jie Zhao , Li Zhang

The financial industry relies on deep learning models for making important decisions. This adoption brings new danger, as deep black-box models are known to be vulnerable to adversarial attacks. In computer vision, one can shape the output…

Machine Learning · Computer Science 2024-08-27 Alina Ermilova , Elizaveta Kovtun , Dmitry Berestnev , Alexey Zaytsev

Deep learning has emerged as a strong and efficient framework that can be applied to a broad spectrum of complex learning problems which were difficult to solve using the traditional machine learning techniques in the past. In the last few…

Machine Learning · Computer Science 2018-10-02 Anirban Chakraborty , Manaar Alam , Vishal Dey , Anupam Chattopadhyay , Debdeep Mukhopadhyay

Machine learning is a modern approach to problem-solving and task automation. In particular, machine learning is concerned with the development and applications of algorithms that can recognize patterns in data and use them for predictive…

We applied machine learning methods to predict chemical hazards focusing on fish acute toxicity across taxa. We analyzed the relevance of taxonomy and experimental setup, showing that taking them into account can lead to considerable…

Quantitative Methods · Quantitative Biology 2022-05-09 Jimeng Wu , Simone D'Ambrosi , Lorenz Ammann , Julita Stadnicka-Michalak , Kristin Schirmer , Marco Baity-Jesi

Recommender systems play a crucial role in helping users to find their interested information in various web services such as Amazon, YouTube, and Google News. Various recommender systems, ranging from neighborhood-based,…

Cryptography and Security · Computer Science 2021-01-11 Hai Huang , Jiaming Mu , Neil Zhenqiang Gong , Qi Li , Bin Liu , Mingwei Xu

Recently supervised machine learning has been ascending in providing new predictive approaches for chemical, biological and materials sciences applications. In this Perspective we focus on the interplay of machine learning algorithm with…

Several websites improve their security and avoid dangerous Internet attacks by implementing CAPTCHAs (Completely Automated Public Turing test to tell Computers and Humans Apart), a type of verification to identify whether the end-user is…

Cryptography and Security · Computer Science 2024-03-21 Jaskaran Singh Walia , Aryan Odugoudar

Recent years witnessed remarkable progress in computational histopathology, largely fueled by deep learning. This brought the clinical adoption of deep learning-based tools within reach, promising significant benefits to healthcare,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-29 Ahmad Obeid , Said Boumaraf , Anabia Sohail , Taimur Hassan , Sajid Javed , Jorge Dias , Mohammed Bennamoun , Naoufel Werghi

With the advancements in Artificial intelligence (AI) and the accumulation of healthrelated big data, it has become increasingly feasible and commonplace to leverage machine learning technologies to analyze clinical and omics metadata to…

Genomics · Quantitative Biology 2022-04-14 Attayeb Mohsen , Lokesh P. Tripathi , Kenji Mizuguchi

We introduce a new computer aided detection and diagnosis system for lung cancer screening with low-dose CT scans that produces meaningful probability assessments. Our system is based entirely on 3D convolutional neural networks and…

Computer Vision and Pattern Recognition · Computer Science 2020-01-22 Onur Ozdemir , Rebecca L. Russell , Andrew A. Berlin

Deep learning (DL) has emerged as a crucial tool in network anomaly detection (NAD) for cybersecurity. While DL models for anomaly detection excel at extracting features and learning patterns from data, they are vulnerable to data…

Skin cancer, the most common human malignancy, is primarily diagnosed visually by physicians [1]. Classification with an automated method like CNN [2, 3] shows potential for challenging tasks [1]. By now, the deep convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2017-03-13 Wenhao Zhang , Liangcai Gao , Runtao Liu

The collection and examination of social media has become a useful mechanism for studying the mental activity and behavior tendencies of users. Through the analysis of collected Twitter data, models were developed for classifying…

Social and Information Networks · Computer Science 2020-03-26 Joseph Tassone , Peizhi Yan , Mackenzie Simpson , Chetan Mendhe , Vijay Mago , Salimur Choudhury