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Reaction-diffusion equations describe various spatially extended processes that unfold as traveling fronts moving at constant velocity. We introduce and solve analytically a model that, besides such fronts, supports solutions advancing as…

Biological Physics · Physics 2026-02-13 Louis Brezin , Kyle J. Shaffer , Kirill S. Korolev

Density-dependent diffusion is a widespread phenomenon in nature. We have examined the density-dependent diffusion behavior of some biological processes such as tumor growth and invasion [23]. Here, we extend our previous work by developing…

Statistical Mechanics · Physics 2022-02-14 Ahmed M. Fouad , Marwa M. Fouad

Training diffusion models is always a computation-intensive task. In this paper, we introduce a novel speed-up method for diffusion model training, called, which is based on a closer look at time steps. Our key findings are: i) Time steps…

Machine Learning · Computer Science 2025-03-26 Kai Wang , Mingjia Shi , Yukun Zhou , Zekai Li , Zhihang Yuan , Yuzhang Shang , Xiaojiang Peng , Hanwang Zhang , Yang You

We investigate travelling wave solutions in reaction-diffusion models of animal range expansion in the case that population diffusion is density-dependent. We find that the speed of the selected wave depends critically on the strength of…

Populations and Evolution · Quantitative Biology 2024-11-19 Beth M. Stokes , Tim Rogers , Richard James

In this paper we propose and validate a multiscale model for the description of particle diffusion in presence of trapping boundaries. We start from a drift-diffusion equation in which the drift term describes the effect of bubble traps,…

Numerical Analysis · Mathematics 2023-07-11 Clarissa Astuto , Antonio Raudino , Giovanni Russo

We use a large single particle tracking data set to analyze the short time and small spatial scale motion of quantum dots labeling proteins in cell membranes. Our analysis focuses on the jumps which are the changes in the position of the…

Quantitative Methods · Quantitative Biology 2015-01-08 Flor A. Espinoza , Stanly L. Steinberg

The diffusive arrival of transcription factors at the promoter sites on the DNA sets a lower bound on how accurately a cell can regulate its protein levels. Using results from the literature on diffusion-influenced reactions, we derive an…

Molecular Networks · Quantitative Biology 2014-10-24 Joris Paijmans , Pieter Rein ten Wolde

In this work, we investigate an intriguing and prevalent phenomenon of diffusion models which we term as "consistent model reproducibility": given the same starting noise input and a deterministic sampler, different diffusion models often…

Machine Learning · Computer Science 2024-06-11 Huijie Zhang , Jinfan Zhou , Yifu Lu , Minzhe Guo , Peng Wang , Liyue Shen , Qing Qu

Proteins are large and complex molecular machines. In order to perform their function, most of them need energy, e.g. either in the form of a photon, like in the case of the visual pigment rhodopsin, or through the breaking of a chemical…

Biomolecules · Quantitative Biology 2009-11-13 Francesco Piazza , Yves-Henri Sanejouand

Diffusion models have gained popularity for generating images from textual descriptions. Nonetheless, the substantial need for computational resources continues to present a noteworthy challenge, contributing to time-consuming processes.…

Computer Vision and Pattern Recognition · Computer Science 2023-11-30 Hanwen Chang , Haihao Shen , Yiyang Cai , Xinyu Ye , Zhenzhong Xu , Wenhua Cheng , Kaokao Lv , Weiwei Zhang , Yintong Lu , Heng Guo

Mechanical coupling between a cell and substrate relies on focal adhesions, clusters of adhesion proteins linking stress fibers (bundles of actin proteins) inside the cell with surrounding tissue. Focal adhesions have been demonstrated to…

Soft Condensed Matter · Physics 2007-05-23 Thomas Bickel , Robijn Bruinsma

A recent experiment [Sadoon AA, Wang Y. 2018 Phys. Rev. E 98, 042411] has revealed that nucleoid associated proteins (i.e., DNA-binding proteins) exhibit highly heterogeneous diffusion processes in bacteria where not only the diffusion…

Statistical Mechanics · Physics 2021-03-09 Yuichi Itto , Christian Beck

Heterogeneous media diffusion is often described using position-dependent diffusion coefficients and estimated indirectly through mean squared displacement in experiments. This approach may overlook other mechanisms and their interaction…

Statistical Mechanics · Physics 2023-09-11 Haroldo V. Ribeiro , Angel A. Tateishi , Ervin K. Lenzi , Richard L. Magin , Matjaz Perc

One-dimensional non-equilibrium models of particles subjected to a coagulation-diffusion process are important in understanding non-equilibrium dynamics, and fluctuation-dissipation relation. We consider in this paper transport properties…

Statistical Mechanics · Physics 2015-06-18 Jean-Yves Fortin

We study protein diffusion in multicomponent lipid membranes close to a rigid substrate separated by a layer of viscous fluid. The large-distance, long-time asymptotics for Brownian motion are calculated using a nonlinear stochastic…

Soft Condensed Matter · Physics 2009-11-11 Yaroslav Tserkovnyak , David R. Nelson

Diffusion maps approximate the generator of Langevin dynamics from simulation data. They afford a means of identifying the slowly-evolving principal modes of high-dimensional molecular systems. When combined with a biasing mechanism,…

Data Analysis, Statistics and Probability · Physics 2020-07-01 Zofia Trstanova , Ben Leimkuhler , Tony Lelièvre

A generalisation of reaction diffusion systems and their travelling solutions to cases when the productive part of the reaction happens only on a surface in space or on a line on plane but the degradation and the diffusion happen in bulk…

Dynamical Systems · Mathematics 2022-01-05 Anton S. Zadorin

We develop a theory of reversible diffusion-controlled reactions with generalized binding/unbinding kinetics. In this framework, a diffusing particle can bind to the reactive substrate after a random number of arrivals onto it, with a given…

Chemical Physics · Physics 2023-10-03 Denis S. Grebenkov

This article demonstrates that flexible and statistically tractable multi-modal diffusion models can be attained by transformation of simple well-known diffusion models such as the Ornstein-Uhlenbeck model, or more generally a Pearson…

Methodology · Statistics 2013-04-04 Julie Forman , Michael Sørensen

Generating novel and functional protein sequences is critical to a wide range of applications in biology. Recent advancements in conditional diffusion models have shown impressive empirical performance in protein generation tasks. However,…

Machine Learning · Computer Science 2025-12-04 Zinan Ling , Yi Shi , Brett McKinney , Da Yan , Yang Zhou , Bo Hui