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Protein structure prediction is pivotal for understanding the structure-function relationship of proteins, advancing biological research, and facilitating pharmaceutical development and experimental design. While deep learning methods and…

Machine Learning · Computer Science 2024-12-30 Kaihui Cheng , Ce Liu , Qingkun Su , Jun Wang , Liwei Zhang , Yining Tang , Yao Yao , Siyu Zhu , Yuan Qi

The diffusion of finite-size hard-core interacting particles in two- or three-dimensional confined domains is considered in the limit that the confinement dimensions become comparable to the particle's dimensions. The result is a nonlinear…

Mathematical Physics · Physics 2017-03-23 Maria Bruna , S. Jonathan Chapman

Experiments measuring contact formation between a probe and quencher in disordered chains provide information on the fundamental dynamical timescales relevant to protein folding, but their interpretation usually relies on simplified…

Soft Condensed Matter · Physics 2016-02-17 Gul Zerze , Jeetain Mittal , Robert B. Best

Intracellular protein patterns govern essential cellular functions by dynamically redistributing proteins between membrane-bound and cytosolic states, conserving their total numbers. This review presents a theoretical framework for…

Biological Physics · Physics 2025-12-16 Erwin Frey , Henrik Weyer

The principle of smooth fit is probably the most used tool to find solutions to optimal stopping problems of one-dimensional diffusions. It is important, e.g., in financial mathematical applications to understand in which kind of models and…

Probability · Mathematics 2014-06-24 Paavo Salminen , Bao Quoc Ta

We extend the Saffman theory of membrane hydrodynamics to account for the correlated motion of membrane proteins, along with the effect of protein concentration on that correlation and on the response of the membrane to stresses.…

Soft Condensed Matter · Physics 2015-05-13 Naomi Oppenheimer , Haim Diamant

Controlling the deposition of filaments, such as nanowires and nanotubes, from evaporating droplets is critical for the performance of emerging technologies like flexible sensors and printed electronics. The final deposit morphology…

Soft Condensed Matter · Physics 2026-02-10 Johannes Schöttner , Qingguang Xie , Gaurav Nath , Jens Harting

The interaction of a protein with its environment can be understood and controlled via its 3D structure. Experimental methods for protein structure determination, such as X-ray crystallography or cryogenic electron microscopy, shed light on…

Machine Learning · Computer Science 2025-04-24 Axel Levy , Eric R. Chan , Sara Fridovich-Keil , Frédéric Poitevin , Ellen D. Zhong , Gordon Wetzstein

A simple and surprisingly accurate description of spectral diffusion in deeply frozen globular proteins is constructed directly using the concept of ultrametricity of protein dynamics. Earlier the similar concept has been used for…

Biomolecules · Quantitative Biology 2008-04-30 Vladik A. Avetisov , Albert Kh. Bikulov

Translation is one of the main steps in the synthesis of proteins. It consists of ribosomes that translate sequences of nucleotides encoded on mRNA into polypeptide sequences of amino acids. Ribosomes bound to mRNA move unidirectionally,…

Subcellular Processes · Quantitative Biology 2022-01-19 Olivier Dauloudet , Izaak Neri , Jean-Charles Walter , Jérôme Dorignac , Frédéric Geniet , Andrea Parmeggiani

Diffusion processes have been widely used for approximations in the queueing theory. There are different types of diffusion approximations. Among them, we are interested in those obtained through limits of a sequence of models which…

Probability · Mathematics 2015-01-20 Masakiyo Miyazawa

Microcavity and whispering gallery mode (WGM) biosensors derive their sensitivity from monitoring frequency shifts induced by protein binding at sites of highly confined field intensities, where field strengths can be further amplified by…

Temporally and spatially resolved measurements of protein transport inside cells provide important clues to the functional architecture and dynamics of biological systems. Fluorescence Recovery After Photobleaching (FRAP) technique has been…

Subcellular Processes · Quantitative Biology 2009-03-04 George D. Tsibidis

In this paper, a diffusion-based molecular communication channel is modeled in presence of a probabilistic absorber. The probabilistic absorber is an absorber which absorbs molecules upon collision with probability q. With random walk…

Emerging Technologies · Computer Science 2019-09-19 S Salehi , NS Moayedian , E Alarcón

For biologically relevant macromolecules such as intrinsically disordered proteins, internal degrees of freedom that allow for shape changes have a large influence on both the motion and function of the compound. A detailed understanding of…

Nucleation processes are at the heart of a large number of phenomena, from cloud formation to protein crystallization. A recently emerging area where nucleation is highly relevant is the initiation of filamentous protein self-assembly, a…

Soft Condensed Matter · Physics 2017-01-05 Anđela Šarić , Thomas C. T. Michaels , Alessio Zaccone , Tuomas P. J. Knowles , Daan Frenkel

For a substance diffusing on a curved surface, we obtain an explicit relation valid for very small values of the time, between the local concentration, the diffusion coefficient, the intrinsic spatial curvature and the time. We recover the…

Biological Physics · Physics 2009-11-10 J. Balakrishnan

In this work, we explore the quantization of diffusion models in extreme compression regimes to reduce model size while maintaining performance. We begin by investigating classical vector quantization but find that diffusion models are…

Computer Vision and Pattern Recognition · Computer Science 2024-11-20 Jie Shao , Hanxiao Zhang , Jianxin Wu

We discuss the diffusion phenomenon in the parabolic and hyperbolic regimes. New effects related to the finite velocity of the diffusion process are predicted, that can partially explain the strange behavior associated to adsorption…

Mathematical Physics · Physics 2014-02-13 A. Sapora , M. Codegone , G. Barbero