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In this paper we propose a new statistical stopping rule for constrained maximum likelihood iterative algorithms applied to ill-posed inverse problems. To this aim we extend the definition of Tikhonov regularization in a statistical…

Numerical Analysis · Mathematics 2012-12-14 Federico Benvenuto , Michele Piana

Deformable medical image registration is a fundamental task in medical image analysis. While deep learning-based methods have demonstrated superior accuracy and computational efficiency compared to traditional techniques, they often…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Ahsan Raza Siyal , Markus Haltmeier , Ruth Steiger , Malik Galijasevic , Elke Ruth Gizewski , Astrid Ellen Grams

Dynamic inverse problems are challenging to solve due to the need to identify and incorporate appropriate regularization in both space and time. Moreover, the very large scale nature of such problems in practice presents an enormous…

Numerical Analysis · Mathematics 2025-01-23 Toluwani Okunola , Mirjeta Pasha , Misha Kilmer , Melina Freitag

We present an implementation of a new approach to diffeomorphic non-rigid registration of medical images. The method is based on optical flow and warps images via gradient flow with the standard $L^2$ inner product. To compute the…

Computer Vision and Pattern Recognition · Computer Science 2019-04-25 Daniel Grzech , Loïc le Folgoc , Mattias P. Heinrich , Bishesh Khanal , Jakub Moll , Julia A. Schnabel , Ben Glocker , Bernhard Kainz

Deformable image registration is fundamental to longitudinal and population analysis. Geometric alignment of the infant brain MR images is challenging, owing to rapid changes in image appearance in association with brain development. In…

Computer Vision and Pattern Recognition · Computer Science 2020-07-07 Dongming Wei , Sahar Ahmad , Yunzhi Huang , Lei Ma , Zhengwang Wu , Gang Li , Li Wang , Qian Wang , Pew-Thian Yap , Dinggang Shen

In a Hilbert setting, for convex differentiable optimization, we consider accelerated gradient dynamics combining Tikhonov regularization with Hessian-driven damping. The Tikhonov regularization parameter is assumed to tend to zero as time…

Optimization and Control · Mathematics 2022-04-01 Hedy Attouch , Aicha Balhag , Zaki Chbani , Hassan Riahi

Convergence guarantees for optimization over bounded-rank matrices are delicate to obtain because the feasible set is a non-smooth and non-convex algebraic variety. Existing techniques include projected gradient descent, fixed-rank…

Optimization and Control · Mathematics 2024-06-21 Quentin Rebjock , Nicolas Boumal

Unsupervised learning strategy is widely adopted by the deformable registration models due to the lack of ground truth of deformation fields. These models typically depend on the intensity-based similarity loss to obtain the learning…

Image and Video Processing · Electrical Eng. & Systems 2021-12-21 Luyi Han , Haoran Dou , Yunzhi Huang , Pew-Thian Yap

Harmonic surface deformation is a well-known geometric modeling method that creates plausible deformations in an interactive manner. However, this method is susceptible to artifacts, in particular close to the deformation handles. These…

Graphics · Computer Science 2014-08-15 Yeara Kozlov , Janick Martinez Esturo , Hans-Peter Seidel , Tino Weinkauf

This paper introduces the use of unbalanced optimal transport methods as a similarity measure for diffeomorphic matching of imaging data. The similarity measure is a key object in diffeomorphic registration methods that, together with the…

Numerical Analysis · Mathematics 2017-06-19 Jean Feydy , Benjamin Charlier , François-Xavier Vialard , Gabriel Peyré

Learning-based deformable image registration (DIR) accelerates alignment by amortizing traditional optimization via neural networks. Label supervision further enhances accuracy, enabling efficient and precise nonlinear alignment of unseen…

Computer Vision and Pattern Recognition · Computer Science 2025-06-13 Hang Zhang , Xiang Chen , Renjiu Hu , Rongguang Wang , Jinwei Zhang , Min Liu , Yaonan Wang , Gaolei Li , Xinxing Cheng , Jinming Duan

In this manuscript we would like to address the classical optimization problem of minimizing a proper, convex and lower semicontinuous function via the second order in time dynamics, combining viscous and Hessian-driven damping with a…

Optimization and Control · Mathematics 2023-03-20 Mikhail Karapetyants

Diffeomorphic registration using optimal control on the diffeomorphism group and on shape spaces has become widely used since the development of the Large Deformation Diffeomorphic Metric Mapping (LDDMM) algorithm. More recently, a series…

Optimization and Control · Mathematics 2015-03-04 Sylvain Arguillère , Michael Miller , Laurent Younes

Medical image registration aims at identifying the spatial deformation between images of the same anatomical region and is fundamental to image-based diagnostics and therapy. To date, the majority of the deep learning-based registration…

Image and Video Processing · Electrical Eng. & Systems 2023-12-05 Anna Reithmeir , Julia A. Schnabel , Veronika A. Zimmer

Spectral Computed Tomography (CT) is an emerging technology that enables to estimate the concentration of basis materials within a scanned object by exploiting different photon energy spectra. In this work, we aim at efficiently solving a…

Optimization and Control · Mathematics 2021-03-26 Alessandro Perelli , Martin S. Andersen

In this paper, we propose a new approach to deformable image registration that captures sliding motions. The large deformation diffeomorphic metric mapping (LDDMM) registration method faces challenges in representing sliding motion since it…

Optimization and Control · Mathematics 2023-03-15 Lili Bao , Jiahao Lu , Shihui Ying , Stefan Sommer

We exploit the similarities between Tikhonov regularization and Bayesian hierarchical models to propose a regularization scheme that acts like a distributed Tikhonov regularization where the amount of regularization varies from component to…

Numerical Analysis · Mathematics 2024-04-10 Daniela Calvetti , Erkki Somersalo

In nonsmooth optimization, a negative subgradient is not necessarily a descent direction, making the design of convergent descent methods based on zeroth-order and first-order information a challenging task. The well-studied bundle methods…

Optimization and Control · Mathematics 2025-05-13 Hanyang Li , Ying Cui

Regularization plays a crucial role in reliably utilizing imaging systems for scientific and medical investigations. It helps to stabilize the process of computationally undoing any degradation caused by physical limitations of the imaging…

Image and Video Processing · Electrical Eng. & Systems 2021-05-26 Manu Ghulyani , Deepak G Skariah , Muthuvel Arigovindan

Variational methods in imaging are nowadays developing towards a quite universal and flexible tool, allowing for highly successful approaches on tasks like denoising, deblurring, inpainting, segmentation, super-resolution, disparity, and…

Optimization and Control · Mathematics 2014-12-16 Martin Burger , Alex Sawatzky , Gabriele Steidl