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Ptychography is an advanced computational imaging technique in X-ray and electron microscopy. It has been widely adopted across scientific research fields, including physics, chemistry, biology, and materials science, as well as in…

Computational Engineering, Finance, and Science · Computer Science 2024-10-14 Xiangyu Yin , Chuqiao Shi , Yimo Han , Yi Jiang

pyspeckit is a toolkit and library for spectroscopic analysis in Python. We describe the pyspeckit package and highlight some of its capabilities, such as interactively fitting a model to data, akin to the historically widely-used splot…

Instrumentation and Methods for Astrophysics · Physics 2022-06-01 Adam Ginsburg , Vlas Sokolov , Miguel de Val-Borro , Erik Rosolowsky , Jaime E. Pineda , Brigitta M. Sipőcz , Jonathan D. Henshaw

The increasing availability of high-quality optical and near-infrared spectroscopic data, as well as advances in modelling techniques, have greatly expanded the scientific potential of spectroscopic studies. However, the software tools…

Instrumentation and Methods for Astrophysics · Physics 2025-12-23 Daniele Gasparri , Lorenzo Morelli , Umberto Battino , Jairo Méndez Abreu , Adriana de Lorenzo-Cáceres

Atom probe tomography (APT) has matured to a versatile nanoanalytical characterization tool with applications that range from materials science to geology and possibly beyond. Already, well over 100 APT microscopes exist worldwide.…

Computational Physics · Physics 2020-04-14 Markus Kühbach , Priyanshu Bajaj , Murat Han Celik , Eric Aimo Jägle , Baptiste Gault

As AI systems advance and integrate into society, well-designed and transparent evaluations are becoming essential tools in AI governance, informing decisions by providing evidence about system capabilities and risks. Yet there remains a…

Parameter extraction for industry-standard device models like ASM-HEMT is crucial in circuit design workflows. However, many manufacturers do not provide such models, leaving users to build them using only datasheets. Unfortunately,…

Hardware Architecture · Computer Science 2025-07-30 Yuang Peng , Jiarui Zhong , Yang Zhang , Hong Cai Chen

X-ray ptychography imaging at synchrotron facilities like the Advanced Photon Source (APS) involves controlling instrument hardwares to collect a set of diffraction patterns from overlapping coherent illumination spots on extended samples,…

Instrumentation and Detectors · Physics 2022-02-10 Ke Yue , Junjing Deng , Yi Jiang , Youssef Nashed , David Vine , Stefan Vogt

We present a method and preliminary results of the image reconstruction in the Jagiellonian PET tomograph. Using GATE (Geant4 Application for Tomographic Emission), interactions of the 511 keV photons with a cylindrical detector were…

Positron emission tomography (PET) imaging is widely used in a number of clinical applications, including cancer and Alzheimer's disease (AD) diagnosis, monitoring of disease development, and treatment effect evaluation. Statistical…

Tissues and Organs · Quantitative Biology 2025-11-07 Akhil Ambekar , Robert Zielinski , Ani Eloyan

Graph rewriting is a popular tool for the optimisation and modification of graph expressions in domains such as compilers, machine learning and quantum computing. The underlying data structures are often port graphs - graphs with labels at…

Data Structures and Algorithms · Computer Science 2025-03-27 Luca Mondada , Pablo Andrés-Martínez

By coupling peptides with DNA tags (i.e., 'barcodes'), it is now possible to harness high-throughput sequencing (HTS) technologies to enable highly multiplexed peptide-based assays, which have a variety of potential applications including…

Quantitative Methods · Quantitative Biology 2020-07-13 Zane W. Fink , Vidal Martinez , John Altin , Jason T. Ladner

In this position paper we describe a general framework for applying machine learning and pattern recognition techniques in healthcare. In particular, we are interested in providing an automated tool for monitoring and incrementing the level…

Computers and Society · Computer Science 2015-12-01 Filippo Maria Bianchi , Enrico De Santis , Hedieh Montazeri , Parisa Naraei , Alireza Sadeghian

We introduce a framework for automatically choosing data structures to support efficient computation of analytical workloads. Our contributions are twofold. First, we introduce a novel low-level intermediate language that can express the…

Databases · Computer Science 2021-12-28 Amir Shaikhha , Marios Kelepeshis , Mahdi Ghorbani

Systematic literature reviews and meta-analyses are essential for synthesizing research insights, but they remain time-intensive and labor-intensive due to the iterative processes of screening, evaluation, and data extraction. This paper…

Computation and Language · Computer Science 2025-10-09 Pouria Rouzrokh , Bardia Khosravi , Parsa Rouzrokh , Moein Shariatnia

In this paper, we present a software framework, S$\pi$RITROOT, which is capable of track reconstruction and analysis of heavy-ion collision events recorded with the S$\pi$RIT time projection chamber. The track-fitting toolkit GENFIT and the…

Statistical modeling is a key element in many scientific fields and especially in High-Energy Physics (HEP) analysis. The standard framework to perform this task in HEP is the C++ ROOT/RooFit toolkit; with Python bindings that are only…

Data Analysis, Statistics and Probability · Physics 2020-05-21 Jonas Eschle , Albert Puig Navarro , Rafael Silva Coutinho , Nicola Serra

AI tools in pathology have improved screening throughput, standardized quantification, and revealed prognostic patterns that inform treatment. However, adoption remains limited because most systems still lack the human-readable reasoning…

Artificial Intelligence · Computer Science 2025-11-18 Yunqi Hong , Johnson Kao , Liam Edwards , Nein-Tzu Liu , Chung-Yen Huang , Alex Oliveira-Kowaleski , Cho-Jui Hsieh , Neil Y. C. Lin

Data processing frameworks are an essential part of HEP experiments' software stacks. Frameworks provide a means by which code developers can undertake the essential tasks of physics data processing, accessing relevant inputs and storing…

PRF is a Java-based framework that allows researchers to build prototypes of test-based generate-and-validate automatic program repair techniques for JVM languages by simply extending it with their patch generation plugins. The framework…

Software Engineering · Computer Science 2020-09-16 Ali Ghanbari , Andrian Marcus

Methods: We have developed a software suite (DataSet Tracker) for real-time analysis designed to run on computers, smartphones, and smart glasses hardware and suitable for resource-constrained, on-the-fly computing in microscopes without…

Quantitative Methods · Quantitative Biology 2025-08-13 Alexandre Matov