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Conventional thermo-statistics address infinite homogeneous systems within the canonical ensemble. (Only in this case this is equivalent to the fundamental microcanonical ensemble.) However, some 170 years ago the original motivation of…

Astrophysics · Physics 2009-11-13 D. H. E. Gross

We present an identity for an unbiased estimate of a general statistical distribution. The identity computes the distribution density from dividing a histogram sum over a local window by a correction factor from a mean-force integral, and…

Computational Physics · Physics 2012-06-04 Cheng Zhang , Jianpeng Ma

Microcanonical thermodynamics allows the application of statistical mechanics both to finite and even small systems and also to the largest, self-gravitating ones. However, one must reconsider the fundamental principles of statistical…

Statistical Mechanics · Physics 2009-11-11 D. H. E. Gross , J. F. Kenney

Phase diagrams serve as a highly informative tool for materials design, encapsulating information about the phases that a material can manifest under specific conditions. In this work, we develop a method in which Bayesian inference is…

Materials Science · Physics 2023-09-06 Timofei Miryashkin , Olga Klimanova , Vladimir Ladygin , Alexander Shapeev

We develop a generalized theory of (meta)equilibrium statistical mechanics in the thermodynamic limit valid for both smooth and fractal phase spaces. In the former case, our approach leads naturally to Boltzmann-Gibbs standard…

Statistical Mechanics · Physics 2009-11-11 V. Garcia-Morales , J. Pellicer

A novel approach designed to directly estimate microcanonical quantities from energy histograms is proposed, which enables the immediate systematic identification and classification of phase transitions in physical systems of any size by…

Statistical Mechanics · Physics 2025-09-25 Michael Bachmann

Calculating free energies is an important and notoriously difficult task for molecular simulations. The rapid increase in computational power has made it possible to probe increasingly complex systems, yet extracting accurate free energies…

Chemical Physics · Physics 2014-07-29 Viveca Lindahl , Jack Lidmar , Berk Hess

Aggregation transitions in disordered mesoscopic systems play an important role in several areas of knowledge, from materials science to biology. The lack of a thermodynamic limit in systems that are intrinsically finite makes the…

Statistical Mechanics · Physics 2022-02-25 L. F. Trugilho , L. G. Rizzi

Equilibrium statistics of Hamiltonian systems is correctly described by the microcanonical ensemble. Classically this is the manifold of all points in the $N-$body phase space with the given total energy. Due to Boltzmann's principle,…

Statistical Mechanics · Physics 2007-05-23 D. H. E. Gross

We show direct formal relationship between the Wang-Landau iteration [PRL 86, 2050 (2001)], metadynamics [PNAS 99, 12562 (2002)] and statistical temperature molecular dynamics [PRL 97, 050601 (2006)], the major Monte Carlo and molecular…

Statistical Mechanics · Physics 2021-05-13 Christoph Junghans , Danny Perez , Thomas Vogel

Microcanonical analysis is a powerful method for studying phase transitions of finite-size systems. This method has been used so far only for studying phase transitions of equilibrium systems, which can be described by microcanonical…

Statistical Mechanics · Physics 2016-06-08 Julian Lee

This paper proposes a symbolic-numeric Bayesian filtering method for a class of discrete-time nonlinear stochastic systems to achieve high accuracy with a relatively small online computational cost. The proposed method is based on the…

Numerical Analysis · Mathematics 2022-03-23 Tomoyuki Iori , Toshiyuki Ohtsuka

Semiclassical instanton theory is a form of quantum transition-state theory which can be applied to computing thermal reaction rates for complex molecular systems including quantum tunneling effects. There have been a number of attempts to…

Chemical Physics · Physics 2020-10-28 Wei Fang , Pierre Winter , Jeremy O. Richardson

To directly simulate rare events using atomistic molecular dynamics is a significant challenge in computational biophysics. Well-established enhanced-sampling techniques do exist to obtain the thermodynamic functions for such systems. But…

Statistical Mechanics · Physics 2020-07-21 Dhiman Ray , Ioan Andricioaei

Equilibrium statistics of Hamiltonian systems is correctly described by the microcanonical ensemble. Classically this is the manifold of all points in the N-body phase space with the given total energy. Due to Boltzmann's principle,…

Statistical Mechanics · Physics 2007-05-23 D. H. E. Gross

Among the statistical mechanical frameworks able to describe systems in non-equilibrium steady states such as collisionless plasmas, self-gravitating systems and other complex systems, superstatistics have gained recent attention.…

Statistical Mechanics · Physics 2026-04-21 Sergio Davis

Microcanonical thermodynamics (MCTh) is contrasted to canonical thermodynamics (CTh). At phase transitions of 1.order the two ensembles are NOT equivalent even in the thermodynamic limit . Energy fluctuations do not vanish and phase…

Statistical Mechanics · Physics 2007-05-23 D. H. E. Gross

The histogram reweighting technique, widely used to analyze Monte Carlo data, is shown to be applicable to dynamic properties obtained from Molecular Dynamics simulations. The theory presented here is based on the fact that the correlation…

Statistical Mechanics · Physics 2009-11-11 Carlos Nieto-Draghi , Javier Perez-Pellitero , Josep Bonet Avalos

Temperature Accelerated Sliced Sampling (TASS) is an efficient method to compute high dimensional free energy landscapes. The original TASS method employs the Weighted Histogram Analysis Method (WHAM) which is an iterative post-processing…

Computational Physics · Physics 2021-10-18 Asit Pal , Subhendu Pal , Shivani Verma , Motoyuki Shiga , Nisanth N. Nair

Computing the equilibrium properties of complex systems, such as free energy differences, is often hampered by rare events in the dynamics. Enhanced sampling methods may be used in order to speed up sampling by, for example, using high…

Computational Physics · Physics 2015-02-11 Antonia S. J. S. Mey , Hao Wu , Frank Noé