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Flattening filter free (FFF) beams due to their non-uniformity, are sub-optimal for larger field sizes. The purpose of this study was to investigate the incident electron beam distributions that would produce flat FFF beams without the use…

Medical Physics · Physics 2015-06-16 Sergei Zavgorodni

In this manuscript, we investigated the accuracy of the entire chain of phase space files generated by the TrueBeam VirtuaLinac system in clinical treatment plans. Good agreement was obtained between the MC simulation and the clinical…

Medical Physics · Physics 2015-09-24 Yue Yan , Poonam Yadav , Daniel Saenz , Bhudatt R. Paliwal

Modulated electron radiotherapy (MERT) and combined, modulated photon/electron radiotherapy (MPERT) have received increased research attention, having shown capacity for reduced low dose exposure to healthy tissue and comparable, if not…

Medical Physics · Physics 2014-10-10 Samantha A. M. Lloyd , Isabelle M. Gagne , Sergei Zavgorodni

Purpose: To evaluate the latent variance (LV) of TrueBeam photon phase-space files (PSF) for open 10x10$cm^2$ and small fields. Methods: BEAMnrc/DOSXYZnrc was used to transport particles from Varian phase-space files (PSFA) through the…

Medical Physics · Physics 2018-01-17 Eyad Alhakeem , Sergei Zavgorodni

The present work is devoted to develop a computational model using the Gate Monte Carlo software for the simulation of a 6MV photon beam given by Elekta Synergy Platform medical linear accelerator treatment head. The model includes the…

Medical Physics · Physics 2013-09-04 Yahya Tayalati , Samir Didi , Mustafa Zerfaoui , Abdellilah Moussaa

Purpose: To develop a Monte Carlo (MC) therapeutic dose calculation toolkit of a recently released ring gantry linac in Geant4 (Version 10.7) for secondary dose validation of radiotherapy plan. Methods: For the Halcyon (Varian Medical…

Medical Physics · Physics 2022-10-04 Ruirui Liu , Zhen Ji , Xiandong Zhao , Tianyu Zhao , Abhishek Sethi , Daren Sawkey , Bin Cai

Purpose/Objective: Backscattered radiation (BSR) into linac monitor chamber has to be accounted for in radiotherapy dose calculations. In Monte Carlo (MC) calculations, the BSR can be modeled explicitly, but only when treatment head…

Medical Physics · Physics 2015-06-16 Sergei Zavgorodni , Eyad Alhakeem , Reid Townson

Purpose: A Monte Carlo (MC) beam model and its implementation in a clinical treatment planning system (TPS, Varian Eclipse) are presented for a modified ultra-high dose-rate electron FLASH radiotherapy (eFLASH-RT) LINAC. Methods: The gantry…

Monte Carlo (MC) is generally considered as the most accurate dose calculation tool for particle therapy. However, a proper description of the beam particles kinematics is a necessary input for a realistic simulation. Such a description can…

The Fermilab Linac delivers a variable intensity, 400-MeV beam to the The MuCool Test Area experimental hall via a beam line specifically designed to facilitate measurements of the Linac beam emittance and properties. A 10 m,…

Accelerator Physics · Physics 2013-01-30 F. G. G. Garcia , C. Johnstone , T. Kobilarcik , G. M. Koizumi , C. D. Moore , D. L. Newhart

Purpose: To investigate the validity of two Monte Carlo simulation absolute dosimetry approaches in the case of a small field dedicated `D'-shaped collimator used for the retinoblastoma treatment with external photon beam radiotherapy.…

Medical Physics · Physics 2018-09-25 P. A. Mayorga , L. Brualla , A. Flühs , W. Sauerwein , A. M. Lallena

This study develops and validates a patient-specific Monte Carlo (MC) dosimetry framework for propagation-based phase-contrast breast CT (BCT) at the Imaging and Medical Beamline (IMBL), ANSTO Australian Synchrotron, for accurate mean…

Objective: To develop and validate an independent Monet Carlo dose calculation engine to support for software verification of treatment planning systems and quality assurance workflow. Method: GATE Monte Carlo toolkit was employed to…

Medical Physics · Physics 2021-07-27 A. Asadi , A. Akhavanallaf , S. A. Hosseini , N. vosoughi , H. Zaidi

Monte Carlo (MC) simulation is considered as the most accurate method for radiation dose calculations. Accuracy of a source model for a linear accelerator is critical for the overall dose calculation accuracy. In this paper, we presented an…

Medical Physics · Physics 2015-03-06 Zhen Tian , Yongbao Li , Michael Folkerts , Feng Shi , Steve B. Jiang , Xun Jia

Standard 6 megavolt (MV) radiotherapy is limited by source size and secondary electron range to minimum radiological penumbra widths of ~2-3 mm. This study investigates sharper beams via upright radiotherapy with lower energies and extended…

Medical Physics · Physics 2026-03-10 Lloyd E Kamole Ghomsi , Clinton Gibson , Veng-Jean Heng , Ramish M Ashraf , Lawrie Skinner

Purpose: Retinoblastoma (RB) is the most common eye tumor in childhood and can be treated external radiotherapy. The purpose of this work is to evaluate the adequacy of Monte Carlo simulations and the accuracy of a commercial treatment…

Medical Physics · Physics 2018-09-26 L. Brualla , P. A. Mayorga , A. Flühs , A. M. Lallena , J. Sempau , W. Sauerwein

The MTA beam line has been specifically designed to facilitate measurements of the Fermilab Linac beam emittance and properties utilizing a long, 10m, element-free straight. Linac beam is extracted downstream of the 400-MeV electrostatic…

Accelerator Physics · Physics 2012-09-26 C. Johnstone

X-ray fluorescence computed tomography based on sheet-beam can save a huge amount of time to obtain a whole set of projections using synchrotron. However, it is clearly unpractical for most biomedical research laboratories. In this paper,…

Medical Physics · Physics 2017-03-07 Shanghai Jiang , Peng He , Luzhen Deng , Mianyi Chen , Biao Wei

Methods: A phase space file in a plane at 202 mm downstream of the beam exit window is generated through tuning parameters to match FDC results with measured or MCNPX Monte Carlo-simulated integrated depth-dose distribution (IDD) and…

Medical Physics · Physics 2023-01-11 Qianxia Wang , Uwe Titt , Radhe Mohan , Fada Guan , Yao Zhao , Ming Yang , Pablo Yepes

Background and purpose: To propose a novel machine learning-based method for reliable and accurate modeling of linac beam data applicable to the processes of linac commissioning and QA. Materials and methods: We hypothesize that the beam…

Medical Physics · Physics 2020-10-07 Wei Zhao , Ishan Patil , Bin Han , Yong Yang , Lei Xing , Emil Schüler
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