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We propose a continuum model for pattern formation, based on the multiphase model framework, to explore in vitro cell patterning within an extracellular matrix. We demonstrate that, within this framework, chemotaxis-driven cell migration…

Cell Behavior · Quantitative Biology 2022-11-21 Georgina Al-Badri , James B. Phillips , Rebecca J. Shipley , Nicholas C. Ovenden

We study the sedimentation of finite-size inertial particles in a Rayleigh-Taylor-like setup using state-of-the-art direct numerical simulations. The falling particles are observed to produce two distinct regions: a leading mixing layer…

Fluid Dynamics · Physics 2026-01-28 Simone Tandurella , Marco Edoardo Rosti , Stefano Musacchio , Guido Boffetta

Rayleigh-B\'enard convection, i.e. the flow of a fluid between two parallel plates that is driven by a temperature gradient, is an idealised setup to study thermal convection. Of special interest are the statistics of the turbulent…

We have conducted laboratory experiments to model important aspects of plumes in mantle convection. We focus on the role of the viscosity ratio U (between the ambient fluid and the plume fluid) in determining the plume structure and…

Fluid Dynamics · Physics 2016-11-01 Vivek N. Prakash , K. R. Sreenivas , Jaywant H. Arakeri

Pushing two fluids with different density one against the other causes the development of the Rayleigh-Taylor instability at their interface, which further evolves in a complex mixing layer. In porous media, this process is influenced by…

Fluid Dynamics · Physics 2020-06-15 G. Boffetta , M. Borgnino , S. Musacchio

A ubiquitous arrangement in nature is a free-flowing fluid coupled to a porous medium, for example a river or lake lying above a porous bed. Depending on the environmental conditions, thermal convection can occur and may be confined to the…

Fluid Dynamics · Physics 2022-12-21 Matthew McCurdy , Nicholas J. Moore , Xiaoming Wang

We present a numerical study of convection in a horizontal layer comprising a fluid-saturated porous bed overlain by an unconfined fluid layer. Convection is driven by a vertical, destabilising temperature difference applied across the…

Fluid Dynamics · Physics 2021-07-07 Thomas Le Reun , Duncan R. Hewitt

A pure and incompressible material is confined between two plates such that it is heated from below and cooled from above. When its melting temperature is comprised between these two imposed temperatures, an interface separating liquid and…

Fluid Dynamics · Physics 2020-02-11 Jhaswantsing Purseed , Benjamin Favier , Laurent Duchemin , Eric W. Hester

We present hydrodynamic equations of compressible fluids in gravity as a generalization of those in the Boussinesq approximation used for nearly incompressible fluids. They account for adiabatic processes taking place throughout the cell…

Soft Condensed Matter · Physics 2009-11-07 Akira Furukawa , Akira Onuki

In this paper, we propose a lattice Boltzmann (LB) model for the generalized coupled cross-diffusion-fluid system. Through the direct Taylor expansion method, the proposed LB model can correctly recover the macroscopic equations. The cross…

Fluid Dynamics · Physics 2021-11-02 Chengjie Zhan , Zhenhua Chai , Baochang Shi

We investigate the effect of dispersion on convection in porous media by performing direct numerical simulations (DNS) in a two-dimensional Rayleigh-Darcy domain. Scaling analysis of the governing equations shows that the dynamics of this…

Fluid Dynamics · Physics 2018-12-12 Baole Wen , Kyung Won Chang , Marc A. Hesse

This note works out an advection-diffusion approximation to the density of a population of E. coli bacteria undergoing chemotaxis in a one-dimensional space. Simulations show the high quality of predictions under a shallow-gradient regime.

Quantitative Methods · Quantitative Biology 2013-02-12 Zahra Aminzare , Eduardo D. Sontag

We investigate the coupling effect of buoyancy and shear based on an annular centrifugal Rayleigh-B\'enard convection (ACRBC) system in which two cylinders rotate with an angular velocity difference. Direct numerical simulations are…

Fluid Dynamics · Physics 2023-07-25 Jun Zhong , Dongpu Wang , Chao Sun

Blood vessels form either when dispersed endothelial cells (the cells lining the inner walls of fully-formed blood vessels) organize into a vessel network (vasculogenesis), or by sprouting or splitting of existing blood vessels…

Tissues and Organs · Quantitative Biology 2008-09-24 Roeland M. H. Merks , Erica D. Perryn , Abbas Shirinifard , James A. Glazier

We report theoretical and experimental investigations of the flow instability responsible for the mushy-layer mode of convection and the formation of chimneys, drainage channels devoid of solid, during steady-state solidification of aqueous…

Fluid Dynamics · Physics 2015-06-03 Jin-Qiang Zhong , Anthony T. Fragoso , Andrew J. Wells , John S. Wettlaufer

Melting and, conversely, solidification processes in the presence of convection are key to many geophysical problems. An essential question related to these phenomena concerns the estimation of the (time-evolving) melting rate, which is…

The collective chemotaxis of multicellular clusters is an important phenomenon in various physiological contexts, ranging from embryonic development to cancer metastasis. Such clusters often display interesting shape dynamics and…

Tissues and Organs · Quantitative Biology 2025-06-03 Monika Sanoria , Gema Malet-Engra , Giorgio Scita , Nir Gov , Ajay Gopinathan

We study instabilities and pattern formation in reaction-diffusion layers that are diffusively coupled. For two-layer systems of identical two-component reactions, we analyze the stability of homogeneous steady states by exploiting the…

Pattern Formation and Solitons · Physics 2015-06-03 Anne J. Catlla , Amelia McNamara , Chad M. Topaz

Non-equilibrium property of turbulence modifies characteristics of turbulent transport. With the aid of response-function formalism, such non-equilibrium effects in turbulent transport can be represented by the temporal variation of the…

Fluid Dynamics · Physics 2023-05-30 Nobumitsu Yokoi

One of simplest examples of navigation found in nature is run-and-tumble chemotaxis. Tumbles reorient cells randomly, and cells can drift toward attractants or away from repellents by biasing the frequency of these events. The post-tumble…

Soft Condensed Matter · Physics 2017-09-14 Julius B. Kirkegaard , Raymond E. Goldstein